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Effect of multidisciplinary team treatment on outcomes of patients with gastrointestinal malignancy

查看全文 作  者:Chang-Zheng [1]Du;Jie [2]Li;Yong [3]Cai;Ying-Shi [4]Sun;Wei-Cheng [5]Xue;Jin [1]Gu 高影响力作者 机构地区:[1]Department of Colorectal Surgery, Peking University School of Oncology, Fucheng Road 52, Haidian District, Beijing 100142, China;[2]Department of Medical Oncology, Peking University School of Oncology, Fucheng Road 52, Haidian District, Beijing 100142, China;[3]Department of Radiotherapy, Peking University School of Oncology, Fucheng Road 52, Haidian District, Beijing 100142, China;[4]Department of Radiology, Peking University School of Oncology, Fu Cheng Road 52, Haidian District, Beijing 100142, China;[5]Department of Pathology, Peking University School of Oncology, Fucheng Road 52, Haidian District, Beijing 100142, China高影响力机构 出  处:《World Journal of Gastroenterology》索引2011年第17卷第15期,共6页高影响力期刊 摘  要:AIM: To evaluate the effect of multidisciplinary team (MDT) treatment modality on outcomes of patients with gastrointestinal malignancy in China. METHODS: Data about patients with gastric and colorectal cancer treated in our center during the past 10 years were collected and divided into two parts. Part 1 consisted of the data collected from 516 consecutive complicated cases discussed at MDT meetings in Peking University School of Oncology (PKUSO) from December 2005 to July 2009. Part 2 consisted of the data collected from 263 consecutive cases of resect-able locally advanced rectal cancer from January 2001 to January 2005. These 263 patients were divided into neoadjuvant therapy (NT) group and control group. Patients in NT group received MDT treatment, namely neoadjuvant therapy + surgery + postoperative adjuvant therapy. Patients in control group underwent direct surgery + postoperative adjuvant therapy. The outcomes in two groups were compared. RESULTS: The treatment strategy was altered after discussed at MDT meeting in 76.81% of gastric cancer patients and in 58.33% of colorectal cancer patients before operation. The sphincter-preservation and local control of tumor were better in NT group than in control group. The 5-year overall survival rate was also higher in NT group than in control group (77.23% vs 69.75%, P = 0.049). CONCLUSION: MDT treatment modality can significantly improve the outcomes of patients with gastrointestinal malignancy in China. 关 键 词:肿瘤患者 治疗方式 消化道 多学科 恶性 数据收集 辅助治疗 对照组
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