An ABA-mimicking ligand that reduces water loss and promotes drought resistance in plants

查看全文 作　　者：Minjie [1]Cao;Xue [1,2]Liu;Yan [3]Zhang;Xiaoqian [3,4]Xue;X [5]EdwardZhou;Karsten [5]Melcher;Pan [1]Gao;Fuxing [1]Wang;Liang [1]Zeng;Yang [6,7]Zhao;Pan [8]Deng;Dafang [8]Zhong;Jian-Kang [1,6]Zhu;H Eric [2,5]Xu;Yong [3]Xu

机构地区：[1]'Shanghai Center for Plant Stress Biology and Shanghai Institute of Plant Physiology and Ecology, Shanghai Institutes of Biological Sei-ences, Chinese Academy of Sciences, 300 Fenglin Road, Shanghai 200032, China;[2]VARI-SIMM Center, Center for Structure and Func-tion of Drug Targets, Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences,Shanghai 201203, China;[3]Institute of Chemical Biology, Guangzhou Institutes of Biomedicine and Health, Chinese Academy ofSciences, No. 190 Kaiyuan Avenue, Guangzhou Science Park, Guangzhou, Guangdong 510530, China,';[4]Shenyang PharmaceuticalUniversity, No.103 Wenhua Road, Shenhe District, Shenyang, Liaoning 110016, China;[5]Laboratory of Structural Sciences, Centerfor Structural Biology and Drug Discovery, Van Andel Research Institute, 333 Bostwick Ave., N.E., Grand Rapids, M149503, USA;[6]Department of Horticulture and Landscape Architecture, Purdue University, West Lafayette, IN 47906, USA,';[7]Shanghai Instituteof Plant Physiology and Ecology, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, 300 Fenglin Road,Shanghai 200032, China,';[8]Shanghai Institute of Materia Mediea, Chinese Academy of Sciences, Shanghai 201203, China

出　　处：《Cell Research》索引2013年第23卷第8期,共12页

摘　　要：Abscisic 酸(骆驼毛的织物) 是最重要的荷尔蒙让植物抵抗干旱和另外的不能生活的压力。骆驼毛的织物直接绑在骆驼毛的织物受体的 PYR/PYL 家庭,导致类型 2C 磷酸酶(PP2C ) 和下游的骆驼毛的织物发信号的激活的抑制。骆驼毛的织物由小分子发信号的干预能帮助植物克服象干旱,寒冷和土壤咸度那样的不能生活的压力,这被想象。然而,由植物酶的化学不稳定性和快速的分解代谢限制骆驼毛的织物本身的实际申请。这里,我们报导一件小分子骆驼毛的织物的鉴定模仿(AM1 ) 那充当骆驼毛的织物受体的家庭的多重成员的有势力使活跃之物。在 Arabidopsis, AM1 激活高度类似于由骆驼毛的织物导致了那的一个基因网络。有 AM1 的处理禁止种子萌芽,阻止叶水损失,并且支持干旱抵抗。我们与 PYL2 骆驼毛的织物受体和 HAB1 PP2C 在建筑群解决了 AM1 的水晶结构,它表明 AM1 调停交往的 gate-latch-lock 网络,在骆驼毛的织物界限 receptor/PP2C 建筑群被保存的一个结构的特征。一起,这些结果证明一件单个小分子骆驼毛的织物模仿能激活多重骆驼毛的织物受体并且保护植物免受水损失和干旱应力的伤害。而且, AM1 复杂水晶结构为设计 ABA-mimicking 小分子的下一代提供一个结构的基础。 关键词：ABA诱导保护植物水分流失模仿抗旱配体干旱胁迫基因网络

相关文献

参考文献（27）
引证文献（23）
耦合文献（0）

参考文献(27)

引证文献(23)

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

An ABA-mimicking ligand that reduces water loss and promotes drought resistance in plants

参考文献(27)

引证文献(23)

用户提示