Acute and chronic toxic effects of Pb^(2+)on polychaete Perinereis aibuhitensis:Morphological changes and responses of the antioxidant system

查看全文 作　　者：Yulu [1]Tian;Hongjun [2]Liu;Qixiang [2]Wang;Jian [2]Zhou;Xuexi [1]Tang

机构地区：[1]College of Marine Life Sciences,Ocean University of China;[2]Marine Biology Institute of Shangdong Province

出　　处：《Journal of Environmental Sciences》索引2014年第26卷第8期,共8页

基　　金：supported by the National Natural Science Foundation of China (No.41206102,31070458);the National Marine Public Welfare Research Project (No.201005007,201305009) 摘　　要：Perinereis aibuhitensis was used to assess adverse biological effects caused by acute and chronic Pb2+exposure in artificial seawater under controlled laboratory conditions. In 96-hr acute toxicity experiments,the morphological changes showed a positive time/dose-dependent tendency,and the 96-hr LC50 value of Pb2+was 686.41 mg/L. The responses of enzymatic and non-enzymatic antioxidants in tissues including catalase(CAT),peroxidase(POD),superoxide dismutase(SOD),glutathione peroxidase(GSH-PX),malondialdehyde(MDA) and the content of total soluble protein(TSP),were investigated on days 1,4,7 and 10 after Pb2+exposure under chronic toxicity testing. Results showed that the activation of the antioxidant system in P. aibuhitensis depended on the Pb2+concentration and the duration of exposure time.Specifically,POD and SOD activities were induced on the first day of the exposure and decreased to the control level on day 10 after exposure. Therefore,these two indexes could be used to indicate oxidative stress associated with P. aibuhitensis exposure to Pb2+. 关键词：急性毒性实验慢性毒性试验双齿围沙蚕形态变化铅暴露抗氧化系统谷胱甘肽过氧化物酶多毛纲

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Acute and chronic toxic effects of Pb^(2+)on polychaete Perinereis aibuhitensis:Morphological changes and responses of the antioxidant system

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引证文献(9)

耦合文献(58)

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