SCF^SImb E3 ligase-mediated degradation of Expanded is inhibited by the Hippo pathway in Drosophila

查看全文 作　　者：Hongtao [1,2]Zhang;Changqing [1]Li;Hanqing [1,2]Chen;Chuanxian [1,2]Wei;Fei [1,2]Dai;Honggang [1,2]Wu;Wen [1,2]Dui;Wu-Min [3]Deng;Renjie [1,4]Jiao

机构地区：[1]State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, the Chinese Academy of Sciences, Datun Road 15, Beo'ing 100101, China;[2]University of Chinese Academy of Sciences, Beijing 100080, China;[3]Department of Biological Science, Florida State University, Tallahassee, Florida 32304-4295, USA;[4]Guangzhou Hoffmann Institute of Immunology, School of Basic Sciences, Guangzhou Medical University, Dongfengxi Road 195, Guangzhou, Guangdong 510182, China

出　　处：《Cell Research》索引2015年第25卷第1期,共17页

基　　金：We thank Drs E Knust, E Verheyen, Z Wang and Y Zhao for fly stocks; Drs I Edery, H McNeill, X Lin, D Pan and Z Yuan for plasmids; Drs R Fehon and K Irvine for anitibodies; William H Palmer, Jennifer Kennedy and Nick Contreras for critical reading of the manuscript. We thank all the Jiao lab members and members from Dr Li Liu and Yan Zhu's lab for stimulating discussions at the joint fly meetings. We are particularly grateful to Xuehong Liang for her technical assistance. This work was financially supported by the National Natural Science Foundation of China (31228015, 31271573, 81470846), the National Basic Research Program of China (973 Program; 2012CB825504) and the Chinese Academy of Sciences (XDA04020413-02). W-M D is supported by NIH R01GM072562 and NSF IOS-1052333. C L is supported by Beijing Natural Science Foundation (5122027). 关键词：连接酶 SCF 河马通路果蝇降解介导膨化

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SCF^SImb E3 ligase-mediated degradation of Expanded is inhibited by the Hippo pathway in Drosophila

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