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Current status of severe fever with thrombocytopenia syndrome in China

查看全文 作  者:Jianbo [1,2]Zhan;Qin [3]Wang;Jing [4]Cheng;Bing [2]Hu;Jing [2]Li;Faxian [2]Zhan;Yi [2]Song;Deyin [1]Guo 高影响力作者 机构地区:[1]Wuhan University School of Basic Medical Sciences, Wuhan 430072, China;[2]Hubei Provincial Center for Disease Control and Prevention, Wuhan 430079, China;[3]Chinese Center for Disease Control and Prevention, Beijing 102206, China;[4]Wuhan University of Science and Technology, Wuhan 430081, China高影响力机构 出  处:《Virologica Sinica》索引2017年第32卷第1期,共12页高影响力期刊 基  金:supported by grants from the China Mega-Project for Infectious Diseases (2012ZX10004207);the China-US Collaborative Program on Emerging and Re-emerging Infectious Diseases (S2012Y03);the key project of the Health Ministry of Hubei Province (JX5A06);the Hubei Provincial Outstanding Medical Academic Leader program 摘  要:Severe fever with thrombocytopenia syndrome(SFTS) is an emerging infectious disease caused by SFTS virus(SFTSV). SFTSV is associated with a high mortality rate and has been reported in China, South Korea and Japan. SFTSV undergoes rapid changes owing to evolution, gene mutations, and reassortment between different strains of SFTSV. In this review, we summarize the recent cases and general properties of SFTS, focusing on the epidemiology, genetic diversity,clinical features, and diagnostics of SFTSV in China. From 2010 to October 2016, SFTS cases were reported in 23 provinces of China, with increased numbers yearly. Infection and death cases are mainly found in central China, where the Haemaphysalis longicornis ticks are spread. The national average mortality rate of SFTS infection was 5.3%, with higher risk to elder people. The main epidemic period was from May to July, with a peak in May. Thus, SFTS reminds a significant public health problem, and development of prophylactic vaccines and effective antiviral drugs will be highly needed. 关 键 词:有 thrombocytopenia 症候群(SFTS ) 的严重发烧 有 thrombocytopenia 症候群病毒(SFTSV ) 的严重发烧 BUNYAVIRIDAE
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