CRISPR-Cas12a has both cis- and trans-cleavage activities on single-stranded DNA

查看全文 作　　者：Shi-Yuan [1,2]Li;Qiu-Xiang [3]Cheng;Jia-Kun [1,2]Liu;Xiao-Qun [1,2]Nie;Guo-Ping [1,4]Zhao;Jin [1]Wang

机构地区：[1]Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 200032 Shanghai, China;[2]University of Chinese Academy of Sciences, 100049 Beijing, China;[3]Shanghai Tolo Biotechnology Company Limited, 200233 Shanghai, China;[4]Department of Microbiology and Li KaShing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Shatin, New Territories, China

出　　处：《Cell Research》索引2018年第28卷第4期,共3页

基　　金：We thank Chao Lei and Qi Li for their helpful discussion, This work was supported by grants from the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB19040200), the Youth Innovation Promotion Association CAS (2017322) and the National Natural Science Foundation of China (31421061, 31430004 and 31300031). 关键词：DNA 搁浅 CIS VIVO 蛋白质染色体 RNA 生成热

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CRISPR-Cas12a has both cis- and trans-cleavage activities on single-stranded DNA

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