Microbial treatment in chronic constipation

查看全文 作　　者：Linsheng [1,2]Huang;Qi [1]Zhu;Xiao [1]Qu;Huanlong [1,2]Qin

机构地区：[1]Department of General Surgery,Shanghai Tenth People's Hospital Affiliated to Tongji University,Shanghai 200072,China;[2]Clinical Medical College of Shanghai Tenth People's Hospital of Anhui Medical University,Shanghai 200072,China

出　　处：《Science China(Life Sciences)》索引2018年第61卷第7期,共9页

基　　金：supported by the National Natural Science Foundation of China(81230057,81200264,81372615,81472262);the Emerging Cutting-Edge Technology Joint Research Projects of Shanghai(SHDC12012106);the Tongji University Subject Pilot Program(162385) 摘　　要：Chronic functional constipation is a kind of common intestinal disease that occurs in children, adults and elderly people. This disease not only causes great influence to physiological function, but also results in varying degrees of psychological barriers. At present, constipation treatments continue to rely on traditional methods such as purgative therapy and surgery. However, these approaches can disrupt intestinal function. Recent research between intestinal diseases and gut microbiota has gradually revealed a connection between constipation and intestinal flora disturbance, providing a theoretical basis for microbial treatment in chronic constipation. Microbial treatment mainly includes probiotic preparations such as probiotics, prebiotics, synbiotics and fecal microbiota transplantation(FMT). Due to its safety, convenience and curative effect, probiotic preparations have been widely accepted, especially gradually developed FMT with higher curative effects. Microbial treatment improves clinical symptoms, promotes the recovery of intestinal flora, and has no complications during the treatment process. Compared with traditional treatments, microbial treatment in chronic constipation has advantages, and is worthy of further promotion from clinical research to clinical application. 关键词：微生物便秘心理障碍植物群疾病成年人 FMT 临床

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Microbial treatment in chronic constipation

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