Photodynamic therapy guidelines for the management of oral leucoplakia

查看全文 作　　者：Qianming [1]Chen;Hongxia [1]Dan;Fan [1]Tang;Jiongke [1]Wang;Xiaoying [1]Li;Junxin [1]Cheng;Hang [1]Zhao;Xin [1]Zeng

机构地区：[1]State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Chinese Academy of Medical Sciences Research Unit of Oral Carcinogenesis and Management, West China Hospital of Stomatology, Sichuan University

出　　处：《International Journal of Oral Science》索引2019年第11卷第2期,共5页

基　　金：supported by grants from the National Natural Science Foundation of China (81572663, 81621062, 81730030, 81771081 and 81520108009);the 111 Project of MOE (B14038), China;the National Health Planning Commission of China (201502018) 摘　　要：With recent developments in photosensitizers and light delivery systems,topical 5-aminolevulinic acid-mediated photodynamic therapy (ALA-PDT) has become the fourth alternative therapeutic approach in the management of oral leucoplakia (OLK) due to its minimally invasive nature,efficacy,and low risk of systemic side effects and disfigurement.This report presents step-by-step guidelines for applying topical ALA-PDT in the management of OLK based on both the clinical experience of the authors and a systematic review of the current literature.Studies using protocols with standardized parameters and randomized clinical trials at multiple centres with adequate sample sizes and both interim and long-term follow-ups are needed before universally applicable guidelines can be produced in this field. 关键词：MANAGEMENT ORAL leucoplakia PHOTOSENSITIZERS ALA-PDT

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Photodynamic therapy guidelines for the management of oral leucoplakia

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