Pathological evidence for residual SARS-CoV-2 in pulmonary tissues of a ready-for-discharge patient

查看全文 作　　者：Xiao-Hong [1]Yao;Zhi-Cheng [1,2]He;Ting-Yuan [3]Li;Hua-Rong [1,2]Zhang;Yan [1,2]Wang;Huaming [4]Mou;Qiaonan [5]Guo;Shi-Cang [1,2,6]Yu;Yanqing [7]Ding;Xindong [1,2]Liu;Yi-Fang [1,2]Ping;Xiu-Wu [1,2]Bian

机构地区：[1]Institute of Pathology&Southwest Cancer Center,Southwest Hospital,Third Military Medical University(Army Medical University),Chongqing 400038,China;[2]Key Laboratory of Tumor Immunopathology,Ministry of Education of China,Chongqing 400038,China;[3]Department of Vascular Surgery,Southwest Hospital,Third Military Medical University(Army Medical University),Chongqing 400038,China;[4]Deportment of Cardiovascular Diseases,Chongqing Three Gorges Central Hospital,Chongqing 404000,China;[5]Department of Pathology,Xinqioo Hospital,Third Military Medical University(Army Medical University),Chongqing 400038,China;[6]Department of Stem Cell and Regenerative Medicine,Southwest Hospital,Third Military Medical University(Army Medical University),Chongqing 400038,China;[7]Department of Pathology,Nan Fang Hospital,Southern Medical University,Gu angzhou 510515,China

出　　处：《Cell Research》索引2020年第30卷第6期,共3页

基　　金：This study was supported by the Emergency Novel Coronavirus Pneumonia Project from the Ministry of Science and Technology of China(2020YFC0844700 to X.W.B.);The Emergency Project from Chongqing Health and Health Commission(2020ZX01 to X.W.B.);from Chongqing Science and Technology Commission(2020NCPZX01 to X.W.B.);Science and Technology Innovation Project of Chongqing Science and Technology Commission(CSTC2017JCYJ-YSZXX0012 to Y.F.P,CSTC2018JCYJAX0538 to Y.W.,and CXQT19013 to X.L.). 摘　　要：Dear Editor,SARS-CoV-2,a novel coronavirus and causing COVID-19,has given rise to a worldwide pandemic.1,2 So far,tens of thousands of COVID-19 patients have been clinically cured and discharged,but multiple COVID-19 cases showed SARS-CoV-2 positive again in discharged patients,3 which raises an attention for the discharged patients.Also,there is an urgent need to understand the pathogenesis of SARS-CoV-2 infection.Here,we conducted postmortem pathologic study in a ready-fordischarge COVID-19 patient who succumbed to sudden cardiovascular accident.Pathological examination revealed SARSCoV-2-viruses remaining in pneumocytes and virus-caused pathological changes in the lungs.Our study provided new insights into SARS-CoV-2 pathogenesis and might facilitate the improvement of clinical guideline for virus containment and disease management. 关键词：PATIENT PATHOLOGICAL discharged

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Pathological evidence for residual SARS-CoV-2 in pulmonary tissues of a ready-for-discharge patient

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