The biology of bone morphogenetic protein signaling pathway in cerebrovascular system

查看全文 作　　者：Haishuang [1,2]Tang;Xiaoxi [1]Zhang;Gaici [1]Xue;Fengfeng [2]Xu;Qingsong [3]Wang;Pengfei [1]Yang;Bo [1]Hong;Yi [1]Xu;Qinghai [1]Huang;Jianmin [1]Liu;Qiao [1]Zuo

机构地区：[1]Department of Neurosurgery,Changhai Hospital,Naval Military Medical University,168 Changhai Road,Shanghai 200433,People’s Republic of China;[2]Naval Medical Center of PLA,Naval Military Medical University,Shanghai 200050,People’s Republic of China;[3]Department of Cardiology,the First Medical Centre,Chinese PLA General Hospital,Beijing 100853,People’s Republic of China

出　　处：《Chinese Neurosurgical Journal》索引2021年第7卷第4期,共8页

基　　金：supported by the National Key Research and Development Program of China(grant No:2016YFC1300703);the National Natural Science Foundation of China(grant No:81701136,81771264). 摘　　要：Bone morphogenetic protein belongs to transcription growth factor superfamilyβ;bone morphogenetic protein signal pathway regulates cell proliferation,differentiation,and apoptosis among different tissues.Cerebrovascular system supplies sufficient oxygen and blood into brain to maintain its normal function.The disorder of cerebrovascular system will result into serious cerebrovascular diseases,which is gradually becoming a major threat to human health in modern society.In recent decades,many studies have revealed the underlying biology and mechanism of bone morphogenetic protein signal pathway played in cerebrovascular system.This review will discuss the relationship between the two aspects,aiming to provide new perspective for non-invasive treatment and basic research of cerebrovascular diseases. 关键词：Bone morphogenetic protein HEMODYNAMIC NEOVASCULARIZATION Cerebrovascular diseases

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The biology of bone morphogenetic protein signaling pathway in cerebrovascular system

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