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The Influence of Diabetes, Hypertension, and Hyperlipidemia on the Onset of Age-Related Macular Degeneration in North China: The Kailuan Eye Study

查看全文 作　　者：ZHANG Yong [1]Peng;WANG Ya [2]Xing;ZHOU Jin [1]Qiong;WANG [1]Qian;YAN Yan [1]Ni;YANG [1]Xuan;YANG Jing [1]Yan;ZHOU Wen [1]Jia;WANG [1]Ping;SHEN [1]Chang;YANG [1]Ming;LUAN Ya [1]Nan;WANG Jin [1]Yuan;WU Shou [3]Ling;CHEN Shuo [4]Hua;WANG Hai [5]Wei;FANG Li [6]Jian;WAN Qian [7]Qian;ZHU Jing [1]Yuan;NIE Zi [1]Han;CHEN Yu [1]Ning;XIE [8]Ying;JONAS [9]JB;WEI Wen [1]Bin 高影响力作者 机构地区：[1]Beijing Tongren Eye Center,Beijing key Laboratory of Intraocular Tumor Diagnosis and Treatment,Beijing Ophthalmology&Visual Sciences Key Lab,Medical Artificial Intelligence Research and Verification Key Laboratoryof the Ministry of Industry and Information Technology,Beijing Tongren Hospital,Capital Medical University,Beijing 100730,China;[2]Beijing Institute of Ophthalmology,Beijing Key Laboratory of Ophthalmology and VisualSciences,Beijing Tongren Eye Center,Beijing Tongren Hospital,Capital Medical University,Beijing 100730,China;[3]Cardiology Department,Kailuan General Hospital,Tangshan 063000,Hebei,China;[4]Health CareCenter,Kailuan Group,Tangshan 063000,Hebei,China;[5]Department of Opthalmology,Fuxing Hospital,CapitalMedical University,Beijing 100038,China;[6]Beijing Liangxiang Hospital,Capital Medical University,Departmentof Ophthalmology,Beijing 102401,China;[7]Department of Ophthalmology,The Second Hospital of Anhui MedicalUniversity,Hefei 230000,Anhui,China;[8]Department of Opthalmology,Shanxi Provincial People's Hospital,Taiyuan 030012,Shanxi,China;[9]Department of Ophthalmology,Medical Faculty Mannheim of the Ruprecht-Karls-University of Heidelberg,Heidelberg,Germany高影响力机构 出　　处：《Biomedical and Environmental Sciences》索引2022年第35卷第7期,共9页高影响力期刊 摘　　要：Objective To analyze the prevalence of dry and wet age-related macular degeneration(AMD)in patients with diabetes,hypertension and hyperlipidemia,and to analyze the risk factors for AMD.Methods A population-based cross-sectional epidemiologic study was conducted involving 14,440 individuals.We assessed the prevalence of dry and wet AMD in diabetic and non-diabetic subjects and analyzed the risk factors for AMD.Results The prevalence of wet AMD in diabetic and non-diabetic patients was 0.3%and 0.5%,respectively,and the prevalence of dry AMD was 17%and 16.4%,respectively.The prevalence of wet AMD in healthy,hypertensive,hyperlipidemic,and hypertensive/hyperlipidemic populations was 0.5%,0.3%,0.2%,and 0.7%,respectively.The prevalence of dry AMD in healthy,hypertensive,hyperlipidemic,and hypertensive/hyperlipidemic populations was 16.6%,16.2%,15.2%,and 17.2%,respectively.Age,sex,body mass index,and use of hypoglycemic drugs or lowering blood pressure drugs were corrected in the risk factor analysis of AMD.Diabetes,diabetes/hypertension,diabetes/hyperlipidemia,and diabetes/hypertension/hyperlipidemia were analyzed.None of the factors analyzed in the current study increased the risk for the onset of AMD.Conclusion There was no significant difference in the prevalence of wet and dry AMD among diabetic and non-diabetic subjects.Similarly,there was no significant difference in the prevalence of wet and dry AMD among subjects with hypertension and hyperlipidemia.Diabetes co-existing with hypertension and hyperlipidemia were not shown to be risk factors for the onset of dry AMD. 关 键 词：DIABETES HYPERTENSION HYPERLIPIDEMIA Age-related macular degeneration PREVALENCE Risk factor
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