m^(6)A-modified RNAs possess distinct poly(A)tails

查看全文 作　　者：Shuang [1,2]Wu;Yiwei [1,2]Zhang;Lan [1,2]Yao;Jiaqiang [1]Wang;Falong [2,3]Lu;Yusheng [2,4]Liu

机构地区：[1]College of Life Science,Northeast Agricultural University,Harbin,Hei Longjiang 150030,China;[2]State Key Laboratory of Molecular Developmental Biology,Institute of Genetics and Developmental Biology,Innovative Academy of Seed Design,Chinese Academy of Sciences,Beijing 100101,China;[3]University of Chinese Academy of Sciences,Beijing 100049,China;[4]College of Life Science,Northeast Forestry University,Harbin,Hei Longjiang 150040,China

出　　处：《Journal of Genetics and Genomics》索引2023年第50卷第3期,共4页

基　　金：supported by the National Key Research and Development Program of China(2020YFA0804000);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDA24020203);the CAS Project for Young Scientists in Basic Research(YSBR-012);the National Natural Science Foundation of China(31970588,32170606,32201060);the Natural Science Foundation of Heilongjiang province(YQ2020C003);the China Postdoctoral Science Foundation(2020M670516,2020T130687);the State Key Laboratory of Molecular Developmental Biology。 摘　　要：N^(6)-methyladenosine(m^(6)A)has been found to be the most common type of post-transcriptional chemical modification in mammalian mRNAs and long non-coding RNAs(lncRNAs)(Dominissini et al.,2012;Meyer et al.,2012).In both mammals and yeast,RNA m^(6)A preferentially occurs in both gene coding regions and 3’untranslated regions(3’-UTRs),implicating its fundamental roles in every aspect of post-transcriptional regulation,including splicing,stability,and translation(Wang et al.,2014,2015;Zhao et al.,2014;Yang et al.,2018b). 关键词：N^(6)-methyladenosine(m^(6)A) preferentially

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m^(6)A-modified RNAs possess distinct poly(A)tails

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