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| 1 | 人血浆硫氧化还原蛋白80随着年龄增长而增加,并在载脂蛋白E基因敲除小鼠中诱导炎症、血管生成和动脉粥样硬化显示文摘硫氧化还原蛋白(thioredoxin,TRX)1是一种普遍存在的12kD的蛋白质,可产生抗氧化和抗炎作用。由巨噬细胞产生的截断形式称为TRX80,其可诱导促炎细胞因子的上调。TRX80还促进小鼠腹膜和人巨噬细胞向促炎M1表型的分化。方法:使用特异性酶联免疫吸附试验测定血浆TRX1和TRX80水平。 | 刘莉 叶鹏 Couchie D Vaisman B Abderrazak A Mahmood DFD Hamza MM Canesi F Diderot V El Hadri K Nègre-Salvayre AE Le Page A Fulop T Remaley AT Rouis M | 2017 | 中华高血压杂志2017，25，6： | 9 |
| 2 | HBV vaccine efficacy and detection and genotyping of vaccineé asymptomatic breakthrough HBV infection in Egypt显示文摘AIM:To evaluate the impact of mass vaccination against the hepatitis B virus (HBV) in Egypt,and to search for vaccinee asymptomatic breakthrough HBV infection and its genotype.METHODS:Seven hundred serum samples from vaccinated children and adults (aged 2-47 years) were used for quantitative and qualitative detection of HBsAb by ELISA.Three hundred and sixty serum samples representing undetectable or low or high HBsAb were screened for markers of active HBV infection (HBsAg,HBcAb (IgG) and HBeAb by ELISA,plus HBsAg by AxSYM) and HBV-DNA genotyping by nested multiplex PCR and by DNA sequencing.RESULTS:It was found that 65% of children aged 2-4 years,and 20.5% aged 4-13 years,as well as 45% adults were good responders to HBV vaccination mounting protective level HBsAb.Poor responders were 28%,59.5% and 34%,and non-responders were 7%,20% and 21% respectively,in the three studied groups.Markers of asymptomatic HBV infections were HBsAg detected by ELISA in 2.5% vs 11.39% by AxSYM.Other markers were HBcAb (IgG) in 1.38%,HBeAb in 0.83%,and HBV-DNA in 7.8%.All had HBV genotype E infection.CONCLUSION:It is concluded that HBV vaccine is efficient in controlling HBV infection among children and adults.The vaccine breakthrough infection was by HBV genotype E.A booster dose of vaccine is recommended,probably four years after initial vaccination. | Eman AE Abushady Magda MA Gameel John D Klena Salwa F Ahmed Kouka SE Abdel-wahab Sanya M Fahmy | 2011 | World Journal of Hepatology2011，3，6： | 5 |
| 3 | A sequence-specific gene correction by an RNA-DNA oligonucleotide in mammalian cells characterized by transfection and nuclear extract using a lacZ shuttle system显示文摘 | Igoucheva O Peritz AE Levy D | 1999 | Gene Ther1999，6，12： | 2 |
| 4 | Totol homocysteine levels in plasma:high-performance liquid choromatographic determination with electrochemical detection and glassy carbon electrode 显示文摘 | Finkelstein AE Boccazzi FO Fridman O | 1998 | J Chromatogr B1998，720，12： | 1 |
| 5 | Effect of lowdose Nacetylcysteine infusion on tourniquetinduced ischaemiareperfusion injury in arthroscopic knee surgery显示文摘 | Saricaoglu F Dal D Salman AE | 2005 | Acta Anaesthesiol Scand2005，49，6： | 1 |
| 6 | Is the adjuvant albendazole treatment really needed with PAIR in the management of liver hydatid cysts a prospective,randomized trial with short-term follow-up results显示文摘 | Akhan O Yildiz AE Akinci D | 2014 | Cardiovasc Intervent Radiol2014，1，： | 1 |
| 7 | Impedance plethysmography and thromboembolic disease显示文摘 | GLEW D COOPER T MITCHELMORE AE | 1992 | Br J Radiol1992，65，： | 1 |
| 8 | Stem cells for myocardial regeneration显示文摘 | Orlic D Hill JM Aral AE | 2002 | Cire Res2002，91，12： | 1 |
| 9 | Clinical experience with transcranial Doppler ultrasonography as a confirmatory test for brain death:a retrospective analysis显示文摘 | Sharma D Souter MJ Moore AE | | 0，，03： | 1 |
| 10 | Preeclampsia is associated with alterations in the p53-pathway in villous trophoblast显示文摘 | Sharp AN Heazell AE Baczyk D | 2014 | PLoS One2014，9，87： | 1 |
| 11 | Enhancer trapping in zebrafish using the Sleeping Beauty transposon 显示文摘 | Balciunas D Davidson AE Sivasubbu S | 2004 | BMC Genomics2004，5，1： | 1 |
| 12 | Genetic polymorphism M235T of angiotensinogen: Effects on endothelial function and arterial stiffness in hypertensives 显示文摘 | Ousoulis D AE Papageorgiou N Chatzistamatiou E | 2012 | Int J Cardiol2012，155，3： | 1 |
| 13 | 2012 ACCF/ AHA/HRS focused update of the 2008 guidelines for device-based therapy of cardiac rhythm abnormalities: a report of the American College of Cardiology Foundation/ American Heart Association Task Force on Practice Guidelines 显示文摘 | Tracy CM Epstein AE Darbar D | 2012 | J Am Coil Cardiol2012，60，14： | 1 |
| 14 | US of the peritoneum显示文摘 | Hanbidge AE Lynch D Wilson SR | | 0，，： | 1 |
| 15 | Databaseresources of the National Center for Biotechnology Informa-tion显示文摘 | WHEELER D L CHAPPEY C LASH AE | 2007 | Nucleic Acids Research2007，28，1： | 1 |
| 16 | Raf kinase inhibitory protein function is regulated via a flexible pocket and novel phosphorylation-dependent mechanism显示文摘 | Granovsky AE Clark MC McElheny D | 2009 | Mol Cell Biol2009，29，5： | 1 |
| 17 | Comparison of real time three-dimensional echocardiography to magnetic resonance imaging for assessment of left ventricular mass显示文摘 | Van den Bosch AE Robbers-Visser D Krenning BJ | 2006 | Am J cardiol2006，97，1： | 1 |
| 18 | Chronic use of the immunomodulating tripeptide feG-COOH in experimental feline asthma显示文摘 | Eberhardt JM AE D CR R | 2009 | Vet Immunol Immunopathol2009，132，24： | 1 |
| 19 | Intra-abdominal pressure increases stiffness of the lumbar spine显示文摘 | Hodges PW Eriksson AE Shirley D | | 0，，09： | 1 |
| 20 | Cystoid macular edema in pseudophakia显示文摘 | Stark WJ Maumence AE Fagadau W Datiles M Baker CC Worthem D | 1984 | Sur? Ophthalmol1984，，： | 1 |
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