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| 1 | HBV vaccine efficacy and detection and genotyping of vaccineé asymptomatic breakthrough HBV infection in Egypt显示文摘AIM:To evaluate the impact of mass vaccination against the hepatitis B virus (HBV) in Egypt,and to search for vaccinee asymptomatic breakthrough HBV infection and its genotype.METHODS:Seven hundred serum samples from vaccinated children and adults (aged 2-47 years) were used for quantitative and qualitative detection of HBsAb by ELISA.Three hundred and sixty serum samples representing undetectable or low or high HBsAb were screened for markers of active HBV infection (HBsAg,HBcAb (IgG) and HBeAb by ELISA,plus HBsAg by AxSYM) and HBV-DNA genotyping by nested multiplex PCR and by DNA sequencing.RESULTS:It was found that 65% of children aged 2-4 years,and 20.5% aged 4-13 years,as well as 45% adults were good responders to HBV vaccination mounting protective level HBsAb.Poor responders were 28%,59.5% and 34%,and non-responders were 7%,20% and 21% respectively,in the three studied groups.Markers of asymptomatic HBV infections were HBsAg detected by ELISA in 2.5% vs 11.39% by AxSYM.Other markers were HBcAb (IgG) in 1.38%,HBeAb in 0.83%,and HBV-DNA in 7.8%.All had HBV genotype E infection.CONCLUSION:It is concluded that HBV vaccine is efficient in controlling HBV infection among children and adults.The vaccine breakthrough infection was by HBV genotype E.A booster dose of vaccine is recommended,probably four years after initial vaccination. | Eman AE Abushady Magda MA Gameel John D Klena Salwa F Ahmed Kouka SE Abdel-wahab Sanya M Fahmy | 2011 | World Journal of Hepatology2011，3，6： | 5 |
| 2 | Gene expression profile of adult human olfactory bulb and embryonic neural stem cell suggests distinct signaling pathways and epigenetic control显示文摘 | Marei HE Ahmed AE Michetti F | 2012 | PLo S One2012，7，33： | 1 |
| 3 | Role of glutathione modulation in acrylonitrile-induced gastric DNA damage in rats显示文摘 | Ahmed AE Nouraldeen AM Abdel Rahman SZ | 1996 | Arch Toxicol1996，70，10： | 1 |
| 4 | Comparative metabolism and disposition of acrylonitrile and methacrylonitrile in rats 显示文摘 | BURKA LT SANCHEZ IM AHMED AE | 1994 | Arch Toxieol1994，68，10： | 1 |
| 5 | Underlying characteristics of patients harboring highly resistant Acinetobacter baumannii 显示文摘 | Mahgoub S Ahmed J Gatt AE | 2002 | Am J Infect Control2002，30，7： | 1 |
| 6 | Underling characteristics of patients harborin highly resistant Acinetobacter baumannii显示文摘 | Mahgou BS Ahmed J Glatt AE | 2002 | Am J Infect Control2002，30，7： | 1 |
| 7 | Underlying characteristics of patients harboring highly resistant Acinetobacter baumannii 显示文摘 | Mahgoubs Ahmed J Glatt AE | 2002 | Am J Infect Control2002，30，7： | 1 |
| 8 | Underlying characteristics of patients harboring highly resistant Acinetobacter baumannii显示文摘 | Mahgoub S Ahmed J Glatt AE | 2002 | Am J Infect Control2002，30，7： | 1 |
| 9 | Differential expression of selected histone modi fi er genes in human solid cancers 显示文摘 | Ozdag H Teschendorff AE Ahmed AA | 2006 | BMC Genomics2006，，7： | 1 |
| 10 | The extraeellular matrix protein tgflfi induces microtubule stabilization and sensitizes ovarian cancers to paelitaxel 显示文摘 | Ahmed AA Mills AD Ibrahim AE | 2007 | Cancer Cell2007，12，6： | 1 |
| 11 | Toxicokinetics of monochloroacetic acid:a whole body autoradiography study显示文摘 | Bhat HK Ahmed AE Ansari GA | 1990 | Toxicology1990，63，1： | 1 |
| 12 | Regulation of interleukin-1 beta -induced chemokine production and matrix metallopteinase 2 activation by epigallocatechin-3-gallate in rheumatoid arthritis synoial fibroblasts显示文摘 | Ahmed S Pakozdi A Koch AE | 2006 | Arthritis Rheum2006，54，8： | 1 |
| 13 | Underlying characteristics of patients harboring highly resistant Acinetobacter baumannii显示文摘 | Mahgoub S Ahmed J Glatt AE | 2002 | Am J Infect Control2002，30，7： | 1 |
| 14 | Underling characteristics of patients harborin highly resistant Acinenobacter baumannii显示文摘 | Mahgou BS Ahmed J Glatl AE | 2002 | Am Infect Control2002，30，7： | 1 |
| 15 | Surrogate markers of disease activity in pa- tients with Takayasu arteritis 显示文摘 | Hoffman GS Ahmed AE | 1988 | Int J CardioI1988，66，1： | 1 |
| 16 | Regulation of Interleukin-1–Induced chemokine productionand matrix metalloproteinase 2 activation by epigallocatechin-3-gallate in heumatoid arthritis synovial fibroblasts显示文摘 | Ahmed S Pakozdi A Koch AE | 2006 | Arthritis & Rheumatism2006，54，8： | 1 |
| 17 | Underlying characteristics of patients harboring highly resistant Acinetobacter baumanni显示文摘 | Mahgoub S Ahmed J Glatt AE | 2010 | Am J Infect Corntrol2010，30，7： | 1 |
| 18 | Early experience with in- travitrealbevacizumab combined with laser treatment for retinopa- thy of prematurity 显示文摘 | Ahmed AE ChannaR Durrani J | 2010 | Middle East Afr J Ophthalmol2010，17，3： | 1 |
| 19 | Role of modulation in acrylonitrile induced gastric DNA damage in rats显示文摘 | Ahmed AE Nouraldeen AM Abdel-Rahman SZ etal | 1996 | Arch Toxicol1996，70，： | 1 |
| 20 | Differential expres- sion of selected histone modifier genes in human solid cancers 显示文摘 | Ozdag H Tesehendorff AE Ahmed AA | 2006 | BMC Genomies2006，，7： | 1 |
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