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| 1 | Acid suppressive drugs and gastric cancer: A meta-analysis of observational studies显示文摘AIM: To evaluate the association between acid suppressive drug use and the development of gastric cancer. METHODS: A systematic search of relevant studies that were published through June 2012 was conducted using the MEDLINE (PubMed), EMBASE, and Cochrane Library databases. The search included observational studies on the use of histamine 2-receptor antagonists (H 2 RAs) or proton pump inhibitors and the associated risk of gastric cancer, which was measured using the adjusted odds ratio (OR) or the relative risk and 95%CI. An independent extraction was performed by two of the authors, and a consensus was reached. RESULTS: Of 4595 screened articles, 11 observational studies (n = 94558) with 5980 gastric cancer patients were included in the final analyses. When all the studies were pooled, acid suppressive drug use was associated with an increased risk of gastric cancer risk (adjusted OR = 1.42; 95%CI: 1.29-1.56, I2 = 48.9%, P = 0.034). The overall risk of gastric cancer increased among H 2 RA users (adjusted OR = 1.40; 95%CI: 1.24-1.59, I2 = 59.5%, P = 0.008) and PPI users (adjusted OR = 1.39; 95%CI: 1.19-1.64, I2 = 0.0%, P = 0.377). CONCLUSION: Acid suppressive drugs are associated with an increased risk of gastric cancer. Further studies are needed to test the effect of acid suppressive drugs on gastric cancer. | Jeong Soo Ahn Chun-Sick Eom Christie Y Jeon Sang Min Park | 2013 | World Journal of Gastroenterology2013，19，16： | 12 |
| 2 | A20 is dynamically regulated in the heart and inhibits the hypertrophic response显示文摘 | Cook S A Novikov M S Ahn Y | 2003 | Circulation2003，108，6： | 8 |
| 3 | Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010显示文摘 | Rafael Lozano Mohsen Naghavi Kyle Foreman Stephen Lim Kenji Shibuya Victor Aboyans Jerry Abraham Timothy Adair Rakesh Aggarwal Stephanie Y Ahn Mohammad A AlMazroa Miriam Alvarado H Ross Anderson Laurie M Anderson Kathryn G Andrews Charles Atkinson Larry M | 2012 | The Lancet . 2012 (9859)2012，，9859： | 7 |
| 4 | Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010显示文摘 | Rafael Lozano Mohsen Naghavi Kyle Foreman Stephen Lim Kenji Shibuya Victor Aboyans Jerry Abraham Timothy Adair Rakesh Aggarwal Stephanie Y Ahn Mohammad A AlMazroa Miriam Alvarado H Ross Anderson Laurie M Anderson Kathryn G Andrews Charles Atkinson Larry M | 2012 | The Lancet2012，，9859： | 5 |
| 5 | Solidification microstructure and M2C carbine decomposition in a spray-formed high-speed steel显示文摘 | Lee E Park W Jung J Y Ahn S | 1998 | Metallurgical and Materials Transactions A1998，29，： | 2 |
| 6 | Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010显示文摘 | Christopher J L Murray Theo Vos Rafael Lozano Mohsen Naghavi Abraham D Flaxman Catherine Michaud Majid Ezzati Kenji Shibuya Joshua A Salomon Safa Abdalla Victor Aboyans Jerry Abraham Ilana Ackerman Rakesh Aggarwal Stephanie Y Ahn Mohammed K Ali Mohammad A | 2012 | The Lancet . 2012 (9859)2012，，9859： | 2 |
| 7 | Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010显示文摘 | Theo Vos Abraham D Flaxman Mohsen Naghavi Rafael Lozano Catherine Michaud Majid Ezzati Kenji Shibuya Joshua A Salomon Safa Abdalla Victor Aboyans Jerry Abraham Ilana Ackerman Rakesh Aggarwal Stephanie Y Ahn Mohammed K Ali Mohammad A AlMazroa Miriam Alvara | 2012 | The Lancet . 2012 (9859)2012，，9859： | 2 |
| 8 | Two DNA polymorphisms is in the lipoprotein lipase gene and their associations with factors related to cardiovascular disease显示文摘 | AHN Y I KAMBOH M I HAMMAN R F | 1993 | J Lipid Res1993，34，3： | 2 |
| 9 | Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010显示文摘 | Rafael Lozano Mohsen Naghavi Kyle Foreman Stephen Lim Kenji Shibuya Victor Aboyans Jerry Abraham Timothy Adair Rakesh Aggarwal Stephanie Y Ahn Mohammad A AlMazroa Miriam Alvarado H Ross Anderson Laurie M Anderson Kathryn G Andrews Charles Atkinson Larry M | 2012 | 2012 (9859)2012，，9859： | 2 |
| 10 | Comparison of the filtration characteristics between attached and suspended growth microorganisms in submerged membrane bioreactor显示文摘 | Lee J Ahn W Y Lee C H | 2001 | Wat Res2001，35，10： | 2 |
| 11 | The effect of pre-irradiation dose intense CHOP on anthracyline resistance in localized nasal NK/ T-cell lymphoma显示文摘 | Lee S H Ahn Y C Kim W S | 2006 | Haematologica2006，91，3： | 1 |
| 12 | A new class of SN2 reactions catalyzed by protic solvents: facile fluorination for isotopic labeling of diagnostic molecules 显示文摘 | Kim D W Ahn D S Oh Y H | 2006 | J Am Chem Soc2006，128，16： | 1 |
| 13 | Outcome of adult severe or very severe aplasfic anemia treated with immunosuppressive therapy compared with bone marrow transplantation: multicenter trial 显示文摘 | Ahn M J Choi J H Lee Y Y | 2003 | Int J Hematol2003，78，2： | 1 |
| 14 | The effects of mesenchymal stem cells transduced with Akt in a porcine myocardial infarction model 显示文摘 | Lira SY Kim YS Ahn Y | 2006 | Cardiovasc Res2006，70，3： | 1 |
| 15 | Overexpression of phos- pholipase D enhances matrix metalloproteinase-2 expression and glioma cell invasion via protein kinase C and protein kinase A/NF-kappaB/Spl-mediated signaling pathways显示文摘 | Park M H Ahn B H Hong Y K | 2009 | Carcino- genesis2009，30，2： | 1 |
| 16 | miR-200 Inhibits lung adenocarcinoma cell invasion and metastasis by targeting Flt1/VEGFRI显示文摘 | ROYBAL J D ZANG Y AHN Y H | 2011 | Mol Cancer Res2011，9，1： | 1 |
| 17 | Antioxidant effect of natural plant extracts on the microencapsulated high oleic sunflower oil显示文摘 | AHN J H KIM Y P SEO E M | 2008 | Journal of Food Engineering2008，84，2： | 1 |
| 18 | Effect of high pressure processing on the quality of squid (Todarodes pacificus) during refrigerated storage 显示文摘 | Gou J Y Lee H Y Ahn J H | 2010 | Food Chemistry2010，119，： | 1 |
| 19 | Inhibition of Wnt signaling by Wise (Sostdcl) and negative feedback from Shh controls tooth num- ber and patterning显示文摘 | Ahn Y Sanderson BW Klein OD | 2010 | Development2010，137，19： | 1 |
| 20 | State-periodic adaptive compensation of cogging and coulomb friction in per- manent magnet linear motors 显示文摘 | Ahn H S Chen Y Q Dou H F | 2005 | IEEE Transactions on Magnetics2005，41，1： | 1 |
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