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| 1 | Dopamine: an immune transmitter显示文摘The dopaminergic system controls several vital central nervous system functions, including the control of movement, reward behaviors and cognition. Alterations of dopaminergic signaling are involved in the pathogenesis of neurodegenerative and psychiatric disorders, in particular Parkinson’s disease, which are associated with a subtle and chronic inflammatory response. A substantial body of evidence has demonstrated the non-neuronal expression of dopamine, its receptors and of the machinery that governs synthesis, secretion and storage of dopamine across several immune cell types. This review aims to summarize current knowledge on the role and expression of dopamine in immune cells. One of the goals is to decipher the complex mechanisms through which these cell types respond to dopamine, in order to address the impact this has on neurodegenerative and psychiatric pathologies such as Parkinson’s disease. A further aim is to illustrate the gaps in our understanding of the physiological roles of dopamine to encourage more targeted research focused on understanding the consequences of aberrant dopamine production on immune regulation. These highlights may prompt scientists in the field to consider alternative functions of this important neurotransmitter when targeting neuroinflammatory/neurodegenerative pathologies. | Sarah Thomas Broome Krystal Louangaphay Kevin AKeay Gian Marco Leggio Giuseppe Musumeci Alessandro Castorina | 2020 | Neural Regeneration Research2020，15，12： | 5 |
| 2 | Alveolar gas exchange in patients with type 2 diabetes mellitus显示文摘 | Guvener N Tutuncu N B Akeay S | 2003 | Endocr J2003，50，6： | 1 |
| 3 | Prevalence of atopy in children with type 1 diabetes mellitus, hepatitis B virus carriers, and healthy children : role of T helper 1 ( Th1) -type immune response 显示文摘 | Cakir M Akeay S Karakas T | 2008 | Allergy Asthma Proc2008，29，2： | 1 |
| 4 | Usefulness of oral dipyridamole therapy for angiographie slow coronary artery flow显示文摘 | Kurtoglu N Akeay A Dindar I | 2001 | Am J Car- dial2001，87，： | 1 |
| 5 | Assessment of atrial eleetromeehanical delay, diastolie funetions, and left atrial meehanieal funetions in patients with type 1 diabetes mellitus显示文摘 | Aear G Akeay A Sokmen A | 2009 | J Am Soe Eehoeardiogr2009，22，6： | 1 |
| 6 | Study of heavy metal pollution and speciation in Buyak Menderes and Gediz river sediments 显示文摘 | Akeay H Oguz A Karapire | 2003 | Water Research2003，37，： | 1 |
| 7 | Automatic Detection of Geospatial Ob- jects Using Multiple Hierarchical Segmentations 显示文摘 | Akeay H G Aksoy S | 2008 | IEEE Trans on Geoscience and Remote Sensing2008，46，7： | 1 |
| 8 | Mediators of inflam- mation in Acute Kidney Injury 显示文摘 | Akeay A Nguyen Q Edelstein C L | 2009 | Mediators Inflamm2009，2009，13： | 1 |
| 9 | Mechanical behavior and fibre dispersion of hybrid steel fibre reinforced self-compacting con- crete显示文摘 | Akeay B Tasdemir MA | 2012 | Constr Build Mater2012，28，： | 1 |
| 10 | Drought-in- duced oxidative damage and antioxidant responses in peanut seedlings 显示文摘 | Celikkol Akeay U Erean O Kavas M | 2010 | Plant Growth Regulation2010，61，1： | 1 |
| 11 | An analysis of decentralizedcollection and processing of end-old-life products显示文摘 | KARAKAYLI I EMIR F H AKEAI I E | 2007 | Journal of Operations Management2007，25，6： | 1 |
| 12 | Exophthalmometrie values in a nor- mal Turkish population living in the northeastern part of Turkey显示文摘 | Bilen H Gullulu G Akeay G | 2007 | Thyroid2007，17，6： | 1 |
| 13 | Plasma and urine earnitine levels and earnitine supplementation in ehildren with malnutrition 显示文摘 | Alp H Orbak Z Akeay F | 1999 | J Trop Pediatr1999，45，5： | 1 |
| 14 | Influence of cyclosporineand taerolimus on serum uric acid levels in stable kidney trans-plantation recipients显示文摘 | Kanbay M Akeay A Huddam B ei al | 2005 | Transplant Proc2005，37，： | 1 |
| 15 | Influence of mechanical boundary conditions on the electrocaloric properties of ferroelectric thin films显示文摘 | Akeay G Alpay S P Rossetti G A | 2008 | Journal of Applied Physics2008，103，02： | 1 |
| 16 | Serum 1,25 dihydroxy vitamin D ( 2,25 (OH)2D3), 25 hydroxy vitamin D (25 (OH)D)and parathormone levels in diabetic retinopathy显示文摘 | Aksoy H Akeay F Kurtul N | 2000 | Clinical Biochemistry2000，33，1： | 1 |
| 17 | Mechanical behavior and fiber dispersion of hybrid steel fiber reinforced self- compacting concrete 显示文摘 | Akeay B Tasdemir M A | 2012 | Construction and Building Materials2012，28，1： | 1 |
| 18 | An insight into instrumental variable frequency-domain subspaee identifieation显示文摘 | Akeay H | 2010 | Automatica2010，46，2： | 1 |
| 19 | IL-33 exacerbates acute kidney injury显示文摘 | Akeay A Nguyen Q He Z | 2011 | J Am See Nephrol2011，22，11： | 1 |
| 20 | Study of heavy metal pollution and speciation in Buyak M enderes and Gediz River sediments显示文摘 | Akeay H Oguz A Karapire C | 2003 | Water Research2003，37，： | 1 |
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