|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Liver transplantation for hepatitis B virus: Decreasing indication and changing trends显示文摘AIM: To evaluate the indication and outcome of hepatitis B virus(HBV)-related liver transplantation(LT) in the era of newer antiviral agents.METHODS: We collected data on all patients who underwent transplantation at King Faisal Specialist Hospital and Research Center.These data included demographic,perioperative and long-term postoperative follow-up data including viral serological markers,HBV DNA,and repeated liver imaging.Between January 1990 and January 2012,133 patients(106 males and 27 females) underwent LT for HBV-related cirrhosis at our center.All patients were followed up frequently during the first year following transplantation,according to our standard protocol; follow-up visits occurred every 3-6 mo thereafter.Breakthrough infection was definedas re-emergence of HBV-DNA or hepatitis B surface antigen(HBs Ag) while on treatment.Five patients transplanted prior to 1992 did not receive immediate posttransplant anti-HBV prophylaxis; all other patients were treated with HBIG and at least one nucleos(t)ide analog.RESULTS: One hundred and thirty-three patients underwent LT for HBV and were followed for a median of 82 mo(range: 1-274).The rates of post-LT survival and HBV recurrence during the follow-up period were 89% and 11%,respectively.The following factors were associated with disease recurrence: younger age(44.3 ± 16.2 years vs 51.4 ± 9.9 years,P = 0.02),positive pretransplant hepatitis B e antigen(HBe Ag)(60% vs 14%,P < 0.0001),detectable pretransplant HBV DNA(60% vs 27%,P = 0.03),positive posttransplant HBs Ag(80% vs 4%,P < 0.0001) and positive posttransplant HBe Ag(27% vs 1%,P < 0.0001).Forty-four(33%) patients had hepatocellular carcinoma(HCC).In the first(pre-2007) group,HBV was the second leading indication for LT after hepatitis C virus infection.A total of 64 transplants were performed,including 46(72%) for decompensated HBV cirrhosis,12(19%) for decompensated cirrhosis complicated by HCC and 6(10%) for compensated cirrhosis complicated by HCC.In the second group,nonalcoholic steatohepatitis surpassed HBV as the second leading indication for LT.A total of 69 HBV related transplants were performed,including 43(62%) for decompensated HBV cirrhosis,7(10%) for decompensated cirrhosis complicated by HCC and 19(27.5%) for compensated cirrhosis complicated by HCC.There was a significant(P = 0.007) increase in the number of transplants for compensated cirrhosis complicated by HCC.CONCLUSION: The use of potent anti-HBV agents has led to a changing trend in the indications for LT.HBV is currently the third leading indication for LT in this hyperendemic area. | Waleed Al-hamoudi Hussien Elsiesy Abdulrahman Bendahmash Nasser Al-masri Safiyya Ali Naglaa Allam Mohammed Al Sofayan Hamad Al Bahili Mohammed Al Sebayel Dieter Broering Sammy Saab Faisal Abaalkhail | 2015 | World Journal of Gastroenterology2015，21，26： | 4 |
| 2 | Novel point mutations and mutational complexes in the enhancer II, core promoter and precore regions of hepatitis B virus genotype D1 associated with hepatocellular carcinoma in Saudi Arabia显示文摘 | Anis Khan Mohammed A. Al Balwi Yasuhito Tanaka Ali Hajeer Faisal M. Sanai Ibrahim Al Abdulkarim Latifah Al Ayyar Motasim Badri Dib Saudi Waleed Tamimi Masashi Mizokami Bandar Al Knawy | 2013 | Int J Cancer2013，，12： | 4 |
| 3 | Drainage vs. non-drainage after cholecystectomy for acute cholecystitis:a retrospective study显示文摘Many surgeons practice prophylactic drainage after cholecystectomy without reliable evidence,this study was conducted to answer the question whether to drain or not to drain after cholecystectomy for acute calculous cholecystitis.A retrospective review of all patients who had cholecystectomy for acute cholecystitis in Aseer Central Hospital,Abha,Saudi Arabia,was conducted from April 2010 to April 2012.Data were extracted from hospital case files.Preoperative data included clinical presentation,routine investigations and liver function tests.Operative data included excessive adhesions,bleeding,bile leak,and drain insertion.Complicated cases such as pericholecystic collections,mucocele and empyema were also reported.Patients who needed therapeutic drainage were excluded.Postoperative data included hospital stay,volume of drained fluid,time of drain removal,and drain site problems.The study included 103 patients allocated into two groups;group A(n = 38) for patients with operative drain insertion and group B(n = 65) for patients without drain insertion.The number of patients with preoperative diagnosis of acute non-complicated cholecystitis was significantly greater in group B(80%) than group A(36.8%)(P < 0.001).Operative time was significantly longer in group A.All patients who were converted from laparoscopic to open cholecystectomy were in group A.Multivariate analysis revealed that hospital stay was significantly(P < 0.001) longer in patients with preoperative complications.There was no added benefit for prophylactic drain insertion after cholecystectomy for acute calculous cholecystitis in non-complicated or in complicated cases. | Mohammed A Bawahab Walid M Abd El Maksoud Saeed A Alsareii Fahad S Al Amri Hala F Ali Abdul Rahman Nimeri Abdul Rahman M Al Amri Adel A Assiri Mohammed I Abdul Aziz | 2014 | The Journal of Biomedical Research2014，28，3： | 3 |
| 4 | Biochar from vegetable wastes:agro-environmental characterization显示文摘Considering the global issue of vegetable wastes generation and its impact on the environment and resources,this study evalu-ated the conversion of four largely produced vegetable wastes(cauliflower,cabbage,banana peels and corn cob residues)into biochar.Each waste was tested individually and as a combined blend to assess feedstock influences on biochar properties.In addition,various pyrolysis temperatures ranging from 300℃ to 600℃ and two particle size fractions(less than 75μm,75-125μm)were considered.Biochars were characterized for various properties that can influence the biochars’effective-ness as a soil amendment.It was found that pyrolysis temperature was the most dominant factor on biochar properties,but that individual feedstocks produced biochars with different characteristics.The biochars had characteristics that varied as follows:pH 7.2-11.6,ECE 0.15-1.00 mS cm^(−1),CEC 17-cmolc kg^(−1)andζ-potential−0.24 to−43 mV.Based on optimal values of these parameters from the literature,cauliflower and banana peels were determined to be the best feedstocks,though mixed vegetable waste also produced good characteristics.The optimum temperature for pyrolysis was around 400℃,but differed slightly(300-500℃)depending on the distinct feedstock.However,smaller particle size of biochar application was always optimal.Biochar yields were in the range of 20-30%at this temperature range,except for corn cobs which were higher.This study demonstrates that pyrolysis of dried vegetable wastes is a suitable waste valorization approach to produce biochar with good agricultural properties. | Snigdhendubala Pradhan Ali H.Abdelaal Kamal Mroue Tareq Al‑Ansari Hamish R.Mackey Gordon McKay | 2020 | Biochar2020，2，4： | 3 |
| 5 | Consensus Statements for Management of Barrett’s Dysplasia and Early-Stage Esophageal Adenocarcinoma, Based on a Delphi Process显示文摘 | Cathy Bennett Nimish Vakil Jacques Bergman Rebecca Harrison Robert Odze Michael Vieth Scott Sanders Laura Gay Oliver Pech Gaius Longcroft–Wheaton Yvonne Romero John Inadomi Jan Tack Douglas A. Corley Hendrik Manner Susi Green David Al Dulaimi Haythem Ali | 2012 | Gastroenterology2012，，2： | 2 |
| 6 | Outcomes of staged hepatectomies for liver malignancy显示文摘Liver malignancies are the fifth most common cause of death worldwide.Surgical intervention with curative intent is the treatment of choice for liver tumors as it provides long-term survival.However,only 20%of patients with metastatic liver lesions can be managed by curative liver resection.In most of the cases,hepatectomy is not feasible because of insufficient future liver remnant(FLR).Two-stage hepatectomy is advocated to achieve liver resection in a patient who is considered to not be a candidate for resection.Procedures of staged hepatectomy include conventional two-stage hepatectomy,portal vein embolization,and associating liver partition and portal vein ligation for a staged hepatectomy.Technical success is high for each of these procedures but variable between them.All the procedures have been reported as being effective in achieving a satisfactory FLR and completing the second-stage resection.Moreover,the overall survival and disease-free survival rates have improved significantly for patients who were otherwise considered nonresectable;yet,an increase in the morbidity and mortality rates has been observed.We suggest that this type of procedure should be carried out in high-flow centers and through a multidisciplinary approach.An experienced surgeon is key to the success of those interventions. | Naif A Albati Ali A Korairi Ibrahim Al Hasan Helayel K Almodhaiberi Abdullah A Algarni | 2019 | World Journal of Hepatology2019，11，6： | 2 |
| 7 | Micronucleus analysis in patients with colorectal adenocarcinoma and colorectal polyps显示文摘AIM:To determine,by counting micronucleus (MN) frequencies,whether chromosomal or DNA damage have an effect on the pathogenesis of early colorectal adenocarcinoma (CRC). METHODS:We analyzed MN frequencies in 21 patients with CRC,24 patients with colon polyps [10 neoplastic polyps (NP) and 14 non-neoplastic polyps (NNP)] and 20 normal controls. RESULTS:MN frequency was significantly increased in CRC patients and in NP patients compared with controls (3.72 ± 1.34,3.58 ± 1.21 vs 1.97 ± 0.81,P < 0.001). However,there was no difference in the MN frequency between CRC patients and NP patients (P > 0.05). Similarly,there was no difference in the MN frequency between NNP patients (2.06 ± 0.85) and controls (P > 0.05). CONCLUSION:Our results suggest increased chromosome/DNA instabilities may be associated with the pathogenesis of early CRC. | Ali Karaman Dogan Nas■r Binici Mehmet E■ref Kabalar Züleyha ■al■ku■u | 2008 | World Journal of Gastroenterology2008，14，44： | 2 |
| 8 | Inter-ethnic marriages and severity of coronary artery disease:A multicenter study of Arabian Gulf States显示文摘AIM To assess the association of inter-ethnic vs intra-ethnic marriage with severity of coronary artery disease(CAD) in men undergoing angiography.METHODS We conducted a prospective multicenter,multi-ethnic,cross sectional observational study at five hospitals in Saudi Arabia and the United Arab Emirates,in which we used logistic regression analysis with and without adjustment for baseline differences. RESULTS Data were collected for 1068 enrolled patients undergoing coronary angiography for clinical indications during the period of April 1^(st),2013 to March 30^(th),2014. Ethnicities of spouses were available only for male patients. Of those enrolled,687 were married men and constituted the cohort for the present analysis. Intra-ethnic marriages were reported in 70% and inter-ethnic marriages in 30%. After adjusting for baseline differences,interethnic marriage was associated with lower odds of having significant CAD [adjusted odds ratio 0.52(95%CI:0.33,0.81)] or multi-vessel disease(MVD) [adjusted odds ratio 0.57(95%CI:0.37,0.86)]. The adjusted association with left main disease showed a similar trend,but was not statistically significant [adjusted odds ratio 0.74(95%CI:0.41,1.32)]. The association between interethnic marriage and the presence of significant CAD and MVD was not modified by number of concurrent wives(P interaction > 0.05 for both).CONCLUSION Among married men undergoing coronary angiography,inter-ethnic,as compared to intra-ethnic,marriage is associated with lower odds of significant CAD and MVD. | Amin Daoulah Salem Al-kaabi Amir Lotfi Mushabab Al-Murayeh S Ali Nasseri Waleed Ahmed Salah N Al-Otaibi Mohamed N Alama Osama E Elkhateeb Amy J Plotkin Majed M Malak Khalid Alshali Mohamed Hamzi Saleh Al Khunein Mohammed Abufayyah Alawi A Alsheikh-Ali | 2017 | World Journal of Cardiology2017，9，4： | 2 |
| 9 | Exhaled Nitric Oxide, Relation Ship to Clinieophysiological Markers of Asthma Severity显示文摘 | Al Ali M K Eames C Howarth P H | 1998 | Respir Med1998，92，： | 1 |
| 10 | Developing a green building assessment tool for developing countries – Case of Jordan显示文摘 | Hikmat H. Ali Saba F. Al Nsairat | 2008 | Building and Environment2008，，5： | 1 |
| 11 | Dynamic Model of a Microturbine used as a Distributed Generator显示文摘 | Amer Al - Hinai Ali Feliachi | 2002 | 0 - 7803 - 7339 - 1/02/2002IEEE2002，07，80： | 1 |
| 12 | Inter - arterial third - generation recombinant tissue plasminogen activator (reteplase) for acute ischemicstroke显示文摘 | Qureshi Al Ali Z Suri M F K | 2001 | Neurosurgery2001，49，1： | 1 |
| 13 | Raf kinase inhibitor protein:mechanism of loss of expression and association with genomic instablility显示文摘 | AlMulla F Hagan S AlAli W | 2008 | J Clin Pathol2008，61，4： | 1 |
| 14 | Massage therapy for osteoarlhrilis of lhe knee:a randomized dose-finding trial显示文摘 | Perlman Al Ali A Njike VY | 2012 | PLoS One2012，7，30： | 1 |
| 15 | Primary non-Hodgkin's lym- phoma of bone: experience of a decade显示文摘 | Qureshi A Ali A Riaz N el al | 2010 | Indian J Pathol Micro- hiol2010，53，2： | 1 |
| 16 | Exhaled nitric oxide:relation ship to clinicophysiological markers of asthma severity显示文摘 | Al Ali MK Eames C Howarth PH | 1998 | Respir Med1998，92，7： | 1 |
| 17 | Novel antisense oligonucleotides targeting TGF-β2 inhibit in vivo scarring and improve surgical outcome显示文摘 | Cordeire MF Mead AL Ali RR | | 0，，： | 1 |
| 18 | Advanced trauma life support,8th editon,the evidence for change显示文摘 | Kortbeek JB Al TSA Ali J | 2008 | J Trauma2008，64，6： | 1 |
| 19 | The International Criteria for Beh?et’s Disease (ICBD): a collaborative study of 27 countries on the sensitivity and specificity of the new criteria显示文摘 | F. Davatchi S. Assaad‐Khalil K.T. Calamia J.E. Crook B. Sadeghi‐Abdollahi M. Schirmer T. Tzellos C.C. Zouboulis M. Akhlagi A. Al‐Dalaan Z.S. Alekberova A.A. Ali A. Altenburg E. Arromdee M. Baltaci M. Bastos S. Benamour I. Ben Ghorbel A. Boyvat L. Carvalho | 2014 | J Eur Acad Dermatol Venereol2014，，3： | 1 |
| 20 | Configurable Multirate Filter Banks显示文摘 | Ali Al - Haj | 2008 | American Journal of Applied Sciences2008，5，7： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员