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| 1 | Glioma extent of resection and its impact on patient outcome显示文摘Neurosurgery. 2008 Apr;62(4):753-64; discussion 264-246.OBJECTIVE: There is still no general consensus in the literature regarding the role of extent of glioma resection in im-proving patient outcome. Although the importance of resection in obtaining tissue diagnosis and alleviating symptoms is clear, | Sanai N Berger MS | 2008 | 中国神经肿瘤杂志2008，6，2： | 82 |
| 2 | Hepatitis B genotypes: Relation to clinical outcome in patients with chronic hepatitis B in Saudi Arabia显示文摘AIM: To identify the most common hepatitis B virus (HBV) genotype in Saudi Arabia, and correlate the prevailing genotypes with the clinical outcome of patients. METHODS: Patients were consecutively recruited from the hepatology clinics of two tertiary care referral cen- ters. Patients were categorized into 4 different groups: group 1, patients with hepatitis B and normal liver en- zymes; group 2, patients with hepatitis B and abnormal liver enzymes but without cirrhosis; group 3, patients with hepatitis B and liver cirrhosis; group 4, patients with hepatitis B and hepatocellular carcinoma. All patients had a positive hepatitis B surface antigen (HBsAg). Ge- notyping of HBV was performed by nested PCR-mediated amplification of the target sequence and hybridization with sequence-specific oligonucleotides. RESULTS: Seventy patients were enrolled in this study. They were predominantly male (72.9%) in their mid- forty’s (mean age 47 years). Forty-nine (70%) patients were hepatitis B envelope antigen (HBeAg) negative. The majority of patients (64%) acquired HBV through unknown risk factors. Hepatitis B genotyping revealed that 57 patients (81.4%) were genotype D, 1 patient (1.4%) had genotype A, 1 patient (1.4%) had geno- type C, and 4 patients (5.7%) had genotype E, while 7 patients (10%) had mixed genotype (4 patients ADG, 1 patient DE, 1 patient DF, and 1 patient ADFG). Based on univariate analysis of genotype D patients, significant predictors of advanced liver disease were age, gender, aspartate transaminase, alanine transaminase, albumin,bilirubin, and alkaline phosphatase (all P < 0.001). In multivariate analysis decreased hemoglobin (r = -0.05; 95% CI: -0.08 to -0.03; P = 0.001) and albumin levels (r = -0.004; 95% CI: -0.007 to -0.001; P = 0.002) were highly significant predictors of advanced liver disease. In patients with HBV genotype D, HBeAg negativity was found to increase across advancing stages of liver dis- ease (P = 0.024). CONCLUSION: This study highlights that the vast ma- jority of Saudi patients with chronic hepatitis B have genotype D. No correlation could be observed between the different genotypes and epidemiological or clinical factors. The relationship between genotype D and HBeAg status in terms of disease severity needs to be further elucidated in larger longitudinal studies. | Ayman A Abdo Badr M Al-Jarallah Faisal M Sanai Ahmad S Hersi Khalid Al-Swat Nahla A Azzam Manal Al-Dukhayil Amira Al-Maarik Faleh Z Al-Faleh | 2006 | World Journal of Gastroenterology2006，12，43： | 7 |
| 3 | Six Minute Walk Test to assess functional capacity in chronic liver disease patients显示文摘AIM: To examine the utility of Six Minute Walk Test (6MWT) in patients with chronic liver disease (CLD). METHODS: Two hundred and fifty subjects between the ages of 18 and 80 (mean 47) years performed 6MWT and the Six Minute Walk Distance (6MWD) was measured. RESULTS: The subjects were categorized into four groups. Group A (n = 45) healthy subjects (control); group B (n = 49) chronic hepatitis B patients; group C (n = 54) chronic hepatitis C patients; group D (n = 98) liver cirrhosis patients. The four groups differed in terms of 6MWDs (P < 0.001). The longest distance walked was 421 ± 47 m by group A, then group B (390 ± 53 m), group C (357 ± 72 m) and group D (306 ± 111 m). The 6MWD correlated with age (r = -0.482, P < 0.01), hemoglobin (r = +0.373, P < 0.001) and albumin (r = +0.311, P < 0.001) levels. The Child-Pugh classification was negatively correlated with the 6MWD in cirrhosis (group D) patients (r = -0.328, P < 0.01). At the end of a 12 mo follow-up period, 15 of the 98 cirrhosis patients had died from disease complications. The 6MWD for the surviving cirrhotic patients was longer than for non-survivors (317 ± 101 vs 245 ± 145 m, P = 0.021; 95% CI 11-132). The 6MWD was found to be an independent predictor of survival (P = 0.024). CONCLUSION: 6MWT is a useful tool for assessing physical function in CLD patients. We suggest that 6MWD may serve as a prognostic indicator in patients with liver cirrhosis. | Hatem F Alameri Faisal M Sanai Manal Al Dukhayil Nahla A Azzam Khalid A Al-Swat Ahmad S Hersi Ayman A Abdo | 2007 | World Journal of Gastroenterology2007，13，29： | 5 |
| 4 | 泰国北部的土地利用与景观动态:三个高地流域变化的评价显示文摘此项研究分析了泰国北部三个高地流域在1954~1992年期间由于人类活动产生的热带森林损耗和破坏情况。在这38年期间,森林覆被减少,衣业覆被增加,人口和人口密度增加,农业从自给型种植向商品作物种植改变。这些变化产生了空间上不同的景观,它反映出该区域的生物和栽培多样性、可持续的资源利用和经济条件。通过定量分析热带森林变化的空间和时间格局,我们试图说明这些高地流域的热带森林景观如何受到物理、生物参数以及社会和经济参数的控制。该研究展示了引起全球生物群落变化的时间和空间事件的等级性。 | Jefferson Fox John Krummel Sanay Yarnasarn Methi Ekasingh Nancy Podger 陈百明 | 1995 | 人类环境杂志1995，24，6： | 4 |
| 5 | Novel point mutations and mutational complexes in the enhancer II, core promoter and precore regions of hepatitis B virus genotype D1 associated with hepatocellular carcinoma in Saudi Arabia显示文摘 | Anis Khan Mohammed A. Al Balwi Yasuhito Tanaka Ali Hajeer Faisal M. Sanai Ibrahim Al Abdulkarim Latifah Al Ayyar Motasim Badri Dib Saudi Waleed Tamimi Masashi Mizokami Bandar Al Knawy | 2013 | Int J Cancer2013，，12： | 4 |
| 6 | Assessment of Alpha-Fetoprotein in the Diagnosis of Hepatocellular Carcinoma in Middle Eastern Patients显示文摘 | Faisal M. Sanai Samia Sobki Khalid I. Bzeizi Shaffi A. Shaikh Khalid Alswat Waleed Al-Hamoudi Majid Almadi Faisal Al Saif Ayman A. Abdo | 2010 | Digestive Diseases and Sciences2010，，12： | 2 |
| 7 | Safety and efficacy of peginterferon-α2a plus ribavirin treatment in renal transplant recipients with chronic hepatitis C显示文摘 | Faisal M. Sanai Dujana Mousa Abdallah Al-Mdani Ghada Al-Shoail Hamad Al-Ashgar Khalid Al Meshari Ahmed Al-Qahtani Mayssa Saadeh Khalid I. Bzeizi Hassan Aleid | 2013 | Journal of Hepatology2013，，6： | 2 |
| 8 | Neural stem cells and the origin of gliomas 显示文摘 | Sanai N Alvarez-Buylla A Berger MS | 2005 | N Engl J Med2005，353，8： | 1 |
| 9 | Unique astrocyte ribbon in adult human brain contains neural stem cells but lacks chain migration显示文摘 | SANAI N TRAMONTIN A D QUINONES-HINOJOSA A | 2004 | Nature2004，427，6926： | 1 |
| 10 | Bypass surgery for complex brain aneurysms: an assessment of intracranialintracranial bypass 显示文摘 | Sanai N Zador Z Lawton MT | 2009 | Neurosurgery2009，65，4： | 1 |
| 11 | Efficacy of lafutidine, a histamine H2-receptor antagonist, for taxane-induced peripheral neuropathy in patients with gynecological malignancies显示文摘 | Hiroaki Nagano Hideomi Sanai Mitsue Muraoka Koichiro Takagi | 2012 | Gynecologic Oncology2012，，1： | 1 |
| 12 | Effects of bathymetry,friction,and rotation on estuary-ocean exchange显示文摘 | VALLE-LEVINSON A REYES C SANAY R | 2003 | Journal of Physical Oceanography2003，33，11： | 1 |
| 13 | Functional outcome after language mapping for glioma resection显示文摘 | Sanai N Zaman M Mitchel S | 2008 | N Engl J Med2008，358，： | 1 |
| 14 | The current role of mic- rosurgery for posterior circulation aneurysms: a selective approach in the endovascular era 显示文摘 | Sanai N Tarapore P Lee AC | 2008 | Neurosurgery2008，62，6： | 1 |
| 15 | A fast method for frequency and time domain simulation of high- speed VLSI interconnects 显示文摘 | Sanaie R Chiprout E Nakhla M S Zhang Q J | 1994 | IEEE Trans Microwave Theory Tech1994，42，12： | 1 |
| 16 | Wind-induced circulation in semienclosed homogeneous,rotating basins显示文摘 | SANAY R VALLE-LEVINSON A | 2005 | Journal of Physical Oceanography2005，35，12： | 1 |
| 17 | Unique as trocyte ribbon in adult human brain contains neural stem cells but lacks chain migration显示文摘 | Sanai N Tramontin AD Quinones-Hinojosa A | 2004 | Nature2004，427，6976： | 1 |
| 18 | Effect of 1-methyl-2-mercapto-5-(3-pyrldyl)-imidazole (KC-6141),an anti-aggregation compound,on experimental thrombosis in rats显示文摘 | Umetsu T Sanai K | 1978 | Thromb Haemost1978，39，1： | 1 |
| 19 | Extensive interstitial collagen deposition on the basement membrane zone in allergic nasal mucosa显示文摘 | Sanai A Nagata H Konno A | 1999 | Acta Otolaryngol1999，119，4： | 1 |
| 20 | Extensive in-terstitial collagen deposition on the basement mem-brane zone in allergic nasal mucosa显示文摘 | SANAI A NAGATA H KONNO A | 1999 | Acta Otolar-yngol1999，119，： | 1 |
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