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25篇 您的检索式:作者名="ALENDA"
    题名 作者 年代 出处 被引量
1Serrated polyposis syndrome:Molecular,pathological and clinical aspects显示文摘Hyperplastic polyps have traditionally been considered not to have malignant potential.New pathological classification of serrated polyps and recent discoveries about the serrated pathway of carcinogenesis have revolutionized the concepts and revitalized the research in this area.Until recently,it has been thought that most colorectal cancers arise from conventional adenomas via the traditional tumor suppressor pathway initiated by a mutation of the APC gene,but it has been found thatthis pathway accounts for only approximately 70%-80% of colorectal cancer(CRC)cases.The majority of the remaining colorectal cancer cases follow an alternative pathway leading to CpG island methylator phenotype carcinoma with BRAF mutation and with or without microsatellite instability.The mechanism of carcinomas arising from this alternative pathway seems to begin with an activating mutation of the BRAF oncogene.Serrated polyposis syndrome is a relatively rare condition characterized by multiple and/or large serrated polyps of the colon.Clinical characteristics,etiology and relationship of serrated polyposis syndrome to CRC have not been clarified yet.Patients with this syndrome show a high risk of CRC and both sporadic and hereditary cases have been described.Clinical criteria have been used for diagnosis and frequent colonoscopy surveillance should be performed in order to prevent colorectal cancer.In this review,we try to gather new insights into the molecular pathogenesis of serrated polyps in order to understand their possible clinical implications and to make an approach to the management of this syndrome.Carla Guarinos Cristina Sánchez-Fortún María Rodríguez-Soler Cristina Alenda Artemio Payá Rodrigo Jover 2012World Journal of Gastroenterology2012,18,20:8
2Detection of BRAF V600E Mutation in Colorectal Cancer显示文摘Susana Benlloch Artemio Payá Cristina Alenda Xavier Bessa Montserrat Andreu Rodrigo Jover Antoni Castells Xavier Llor F. Ignacio Aranda Bartomeu Massutí 2006The Journal of Molecular Diagnostics2006,,5:1
3Utility of pl6immunohistochemisty for the identification of Lynch syn-drome 显示文摘Paya A Alenda C Perez - Carbonell L 2009Clin CancerRes2009,15,9:1
4Economic weights for a selection index in Avilen? a purebred beef cattle 显示文摘Ferna'ndez-Perea M T Alenda Jime' nez R 2004Livestock Production Science2004,89,:1
5Genetic parameters for fe- male fertility traits and a fertility index in Spanish dairy cattle显示文摘Gonzdlez-Recio O Alenda R 2005J Dairy Sci2005,88,9:1
6Efficient synthesis of calix tmpa: a new calix azacryptand with unique conformational and host - guest properties 显示文摘Zeng X S Coquiere D Alenda A 2006Chemistry A European Journal2006,12,24:1
7Secretory carcinoma of the male breast: correlation of aspiration cytology and pathology显示文摘Alenda C Aranda FI Segul FJ 2005Diagn Cytopathol2005,32,1:1
8Detection of BRAF V600E Mutation in Colorectal Cancer显示文摘Susana Benlloch Artemio Pay Cristina Alenda 2006J Mol Diagn2006,8,5:1
9Hepatotoxicity related to paraquat and diquat absorption through intact skin显示文摘Peiro AM Zapater P Alenda C 2007Dig Dis Sci2007,52,11:1
10Impact of the primary Gleason pattern on biochemical recurrence-free survival after radical prostatectomy:a single-center cohort of 1248 patients with Gleason 7 tumors显示文摘Alenda O Plpussard G Mouracade P 2011World J Urol2011,29,5:1
11Genetic parameters and consequences of selection for growth traits in a beef herd selected for yearling weight显示文摘ALENDA R 1987J Anim Sci1987,64,2:1
12Hepatotoxicity related to paraquat and diquat absorption through intact skin 显示文摘Peiro AM Zapater P Alenda C 2007Dig Dis Sci2007,52,11:1
13Transketolase-like 1 expression is modulated during colorec-tal cancer progression and metastasis formation显示文摘Diaz-Moralli S Tarrado-Castellarnau M Alenda C 0,,09:1
14Expression of molecular markers in mediastinal nodes from resected stage I non-small-cell lung cancer (NSCLC):prognostic impact and po-tential role as markers of occult micrometastases显示文摘Benlloch S Galbis-Caravajal JM Alenda C 0,,1:1
15Prevalence of Lynch Syndrome among Patients with Newly Diagnosed Endometrial Cancers显示文摘Egoavil C Alenda C Castillejo A 2013P LoS One2013,8,79:1
16Transketolase-like 1 expression is modulated during colorectal cancer progression and metastasis formation 显示文摘Diaz-Moralli S Tarrado-Castellarnau M Alenda C 2011PLoS One2011,6,25:1
17Expression of molecular markers in mediastinal nodes from resected stage I non- small-cell lung cancer (NSCLC): prognostic impact and potential role as markers of occult micrometastases 显示文摘Benlloch S Galbis-Caravajal JM Alenda C 2009Ann Oncol2009,20,1:1
18Efficient synthesis of calix6 tmpa:A new calix6 azacryptandwith unique conformational and host-guest properties显示文摘Zeng Xianshun David Coquière Aurélie Alenda 2006ChemEur J2006,12,:1
19Im- pact of the primary Gleason pattern on biochemical recurrence- free survival after radical prostatectomya single-center cohort of 1,248 patients with Gleason 7 tumors显示文摘ALENDA O PLOUSSARD G MOURACADE P 2011World J Urol2011,29,5:1
20Impact of the primary Gleason pattern on biochemical recurrence-free survival after radical prostatectomy:a single-center cohort of 1248 patients with Gleason 7 tumors显示文摘ALENDA O PLOUSARD G MOURACADE P 0,,:1
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