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| 1 | Development of an Arabic version of the National Eye Institute Visual Function Questionnaire as a tool to study eye diseases patients in Egypt显示文摘AIM:To develop and test an Arabic version of the National Eye Institute Visual Function Questionnaire-25(NEI-VFQ-25).METHODS:NEI-VFQ-25 was translated into Arabic according to WHO translation guidelines. We enrolled adult consenting patients with bilateral chronic eye diseases who presented to 14 hospitals across Egypt from October to December 2012, and documented their clinical findings. Psychometric properties were then tested using STATA.RESULTS:We recruited 379 patients, whose mean age was(54.5±15)y. Of 46.2% were males, 227 had cataract,31 had glaucoma, 23 had retinal detachment, 37 had diabetic retinopathy, and 61 had miscellaneous visual defects. Non-response rate and the floor and ceiling numbers of the Arabic version(ARB-VFQ-25) were calculated. Internal consistency was high in all subscales(except general health), with Cronbach-α ranging from0.702-0.911. Test-retest reliability was high(intraclass correlation coefficient 0.79).CONCLUSION:RB-VFQ-25 isareliableandvalidtool for assessing visual functions of Arabic speaking patients. However, some questions had high non-response rates and should be substituted by available alternatives. Our results support the importance of including self-reported visual functions as part of routine ophthalmologic examination. | Nizar Saleh Abdelfattah Mohamed Amgad Ahmed A Salama Marina E Israel Ghada A Elhawary Ahmed E Radwan Mohamed M Elgayar Tamer M EL Nakhal Islam T Elkhateb Heba A Hashem Doha K Embaby Amira A Elabd Reem K Elwy Magdi S Yacoub Hamdy Salem Mohamed Abdel-Baqy Ahmad Kassem | 2014 | International Journal of Ophthalmology(English edition)2014，7，5： | 8 |
| 2 | Hepatitis B genotypes: Relation to clinical outcome in patients with chronic hepatitis B in Saudi Arabia显示文摘AIM: To identify the most common hepatitis B virus (HBV) genotype in Saudi Arabia, and correlate the prevailing genotypes with the clinical outcome of patients. METHODS: Patients were consecutively recruited from the hepatology clinics of two tertiary care referral cen- ters. Patients were categorized into 4 different groups: group 1, patients with hepatitis B and normal liver en- zymes; group 2, patients with hepatitis B and abnormal liver enzymes but without cirrhosis; group 3, patients with hepatitis B and liver cirrhosis; group 4, patients with hepatitis B and hepatocellular carcinoma. All patients had a positive hepatitis B surface antigen (HBsAg). Ge- notyping of HBV was performed by nested PCR-mediated amplification of the target sequence and hybridization with sequence-specific oligonucleotides. RESULTS: Seventy patients were enrolled in this study. They were predominantly male (72.9%) in their mid- forty’s (mean age 47 years). Forty-nine (70%) patients were hepatitis B envelope antigen (HBeAg) negative. The majority of patients (64%) acquired HBV through unknown risk factors. Hepatitis B genotyping revealed that 57 patients (81.4%) were genotype D, 1 patient (1.4%) had genotype A, 1 patient (1.4%) had geno- type C, and 4 patients (5.7%) had genotype E, while 7 patients (10%) had mixed genotype (4 patients ADG, 1 patient DE, 1 patient DF, and 1 patient ADFG). Based on univariate analysis of genotype D patients, significant predictors of advanced liver disease were age, gender, aspartate transaminase, alanine transaminase, albumin,bilirubin, and alkaline phosphatase (all P < 0.001). In multivariate analysis decreased hemoglobin (r = -0.05; 95% CI: -0.08 to -0.03; P = 0.001) and albumin levels (r = -0.004; 95% CI: -0.007 to -0.001; P = 0.002) were highly significant predictors of advanced liver disease. In patients with HBV genotype D, HBeAg negativity was found to increase across advancing stages of liver dis- ease (P = 0.024). CONCLUSION: This study highlights that the vast ma- jority of Saudi patients with chronic hepatitis B have genotype D. No correlation could be observed between the different genotypes and epidemiological or clinical factors. The relationship between genotype D and HBeAg status in terms of disease severity needs to be further elucidated in larger longitudinal studies. | Ayman A Abdo Badr M Al-Jarallah Faisal M Sanai Ahmad S Hersi Khalid Al-Swat Nahla A Azzam Manal Al-Dukhayil Amira Al-Maarik Faleh Z Al-Faleh | 2006 | World Journal of Gastroenterology2006，12，43： | 7 |
| 3 | Evaluation of an educational training programme for the development of trainers in child mental health in Alexandria显示文摘 | Amira G S E D Faten A K Randa M | 1996 | East Med Health1996，2，3： | 1 |
| 4 | Therapeutic Effect of Dimethyl Dimethoxy Biphenyl Dicarboxylate on Collagen-Induced Arthritis in Rats显示文摘Objective:To study the effect of oral administration of dimethyl dimethoxy biphenyl dicarboxylate(DDB) on adjusting angiogeneic/inflammatory mediators and ameliorating the pathology of bones in rats with collagen-induced arthritis(CIA).Methods:Wistar rat model of CIA was set up using bovine collagen type Ⅱ.Fifty rats were divided into five groups randomly:normal,CIA model,DDB treatment,methotrexate(MTX) treatment,and combined DDB+MTX treatment.Ankle joints of rats were imaged with digital X-ray machine to show the destruction of joints.Fore and hind paw and knee joints were removed above the ankle joint then processed for haematoxylin and eosin staining.Plasma levels of vascular endothelial growth factor(VEGF),platelet derived growth factor,interleukin-8(IL-8),IL-4,tumor necrosis factor α(TNF-α),and cyclooxygenase-2(COX-2) were quantified by enzyme-linked immunosorbent assay.Nitric oxide levels were detected by Griess reagent.Results:Compared with the CIA model group,a remarkable reduction in various angiogenic(VEGF and IL-8) and inflammatory mediators(TNF-α,IL-4 and COX-2) after treatment with DDB either alone or combined with MTX(P<0.05 or P<0.01).Histopathological and X-ray findings were confirmatory to the observed DDB anti-arthritic effect.The DDB-treated group showed amelioration in signs of arthritis which appeared essentially similar to normal.Conclusion:Our data shed light on the therapeutic efficacy of DDB in experimental rheumatoid arthritis(RA) compared with a choice drug(MTX) and it may be offered as a second-line drug in the treatment of RA. | Roba M Talaat Amira S Abo-EI-Atta Sabah M Farou Karima I EI-Dosoky | 2015 | Chinese Journal of Integrative Medicine2015，21，11： | 1 |
| 5 | Effects of Quercus ilex and Punica granarum polyphenols against ethanol-induced gastric damage in rats显示文摘 | Khennouf J S Glarzouli K Amira S | 1999 | Journal of Pharmazie1999，14，1： | 1 |
| 6 | Impact of reconstruction methods and pathological factors on survival after pancreaticoduodenectomy显示文摘 | Binziad S Salem AA Amira G | 2013 | South Asian J Cancer2013，2，3： | 1 |
| 7 | FPGA implementations of fast Fourier transforms for real-time signal and image processing显示文摘 | Uzun I S Amira A Bouridane A | | 0，，03： | 1 |
| 8 | Non-invasive molecular detection of bladder cancer recurrence显示文摘 | Mourah S Rozet F | 2002 | Int J Cancer2002，101，3： | 1 |
| 9 | Friction capacity of axially loaded model pile in sand显示文摘 | AMIRA M YOKOYAMA Y IMAIZUMI S | 1995 | Soils and Foundations1995，35，1： | 1 |
| 10 | FPGA reali-zation of FIR filters by efficient and flexible systoliza-tion using distributed arithmetic 显示文摘 | Meher P K Chandrasekaran S Amira A | | 0，，07： | 1 |
| 11 | FPGA Implementations of Fast Fourier Transforms for Real-Time Signal and Image Processing显示文摘 | Uzun I S Amira A Bouridane A | 2005 | IEE Proeedings Vision Image & Signal processing2005，152，3： | 1 |
| 12 | In vitro spermicidal activity of peptides from amphibian skin:Dermaseptin S4 and derivatives显示文摘 | Amira Z Catherine S Frederic T | 2011 | Bioorganic & Medicinal Chemistry2011，16，： | 1 |
| 13 | MicroRNAs 146a and 147b Biomarkers for Colorectal Tumor’s Localization显示文摘 | Inés Omrane Nadia Kourda Nejla Stambouli Maud Privat Imen Medimegh Amira Arfaoui Nancy Uhrhammer Karim Bougatef Olfa Baroudi Hassen Bouzaienne Raja Marrakchi Yves-Jean Bignon Amel Benammar-Elgaaied Peng Zhang | 2014 | BioMed Research International2014，，： | 1 |
| 14 | Application of reactive cyclodextrin poly butyl acrylate preformed polymers containing nano-ZnO to cot- ton fabrics and their impact on fabric performance显示文摘 | AMIRA E S SHAARAWY S HEBEISH A | 2010 | Carbohydr Polym2010，79，： | 1 |
| 15 | FPGA realization of FIR filters by efficient and flexible systolization using distributed arithmetic显示文摘 | Meher P K Chandrasekaran S Amira A | 2008 | Signal Processing IEEE Transactions on2008，56，7： | 1 |
| 16 | FPGA realization of FIR filters by efficient and flexible systolization using distributed arithmetic显示文摘 | MEHER P K CHANDRASEKARAN S AMIRA A | 2008 | IEEE Transactions on Signal Processing2008，56，7： | 1 |
| 17 | FPGA realization of FIR filters by efficient and flexible systolization using distributed arithmetic 显示文摘 | Meher P K Chandrasekaran S Amira A | 2008 | IEEE Transactions on Signal Processing2008，56，7： | 1 |
| 18 | New sizing agents and flocculants derived from chitosan 显示文摘 | Hebeish A Higazy A Amira E S | 2006 | Starch/Staerke2006，58，8： | 1 |
| 19 | Impact of reconstruction methods and pathological factors on survival after pancreaticoduodenectomy 显示文摘 | Binziad S Salem AA Amira G | 2013 | South Asian J Cancer2013，2，3： | 1 |
| 20 | Assessment of automated DNA extraction coupled with real time PCR for measuring Epstein-Barr virus load in whole blood,peripheral mononuclearcells and plasma显示文摘 | Amira Fafi Kremer Karen Brengel Pesce Gérard Barguès | 2004 | J Clin Virol2004，30，2： | 1 |
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