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| 1 | Hypofractionated stereotactic rad iotherapy alone without whole-brain irradiation for patien ts with solitary and oligo brain metastasis using noninvasive fixation of the skull显示文摘To evaluate the efficacy and toxicity of hypofractionated stereotactic radiotherapy(HSRT)using noninvasive fixation of the sk ull on solitary or oligo brain metastatic p atients as an alternative to stereotactic radiosurgery(SRS)using invasive fixation.The subjects were 87patients who had 4or fewer brain meta stases(50solitary,37oligometastases).Treatment was conducted on 159meta stases by using a linac-based stereotactic system.T he median isocentric dose was 35Gy in4fractions.Whole-brain irradiati on was not applied as an initial treatment.For the salvage treatmen t of metachronous brain metastases,repeat HSRT or whole-brain irradiation was applied.The actuarial1-year local tumor control rate was 81%.Treatment-related complicatio ns were observed in 4patients in the e arly period(<3months)and in 2patients in the late period.T he median survival period was 8.7mon ths.Metachronous brain metastases occurred in 30patients,and none of the 18patients who were eligible for salvage HSRT refused to re ceive it again.Hypofractionated stereotactic radiotherapy achieved tumor control and survival equivalent to those of SRS reported i n the literature.The results suggested that HSRT could be an alternative for solitary or oligo br ain metastatic patients with less to xicity and less invasiveness compared to | Aoyama H Shirato H Onimaru R Kagei K Ikeda J Ishii N Sawamura Y Miyasaka K | 2003 | 癌症2003，22，7： | 12 |
| 2 | 超重和肥胖的全球趋势及其与心血管疾病发生率之间的关系显示文摘虽然超重和肥胖的全球发病率逐日上升,但在不同地区、国家和性别中的发病趋势仍存在差异。据世界卫生组织报道,全球多个地区由体质量指数(body mass index,BMI)≥25kg/m2定义的超重/肥胖发生率几乎接近一半人口,有的甚至超过了一半,如美洲(61.1%),欧洲(54.8%)和东地中海地区(46.0%),然而,在非洲(26.9%),东南亚(13.7%)和西太平洋地区(25.4%),超重/肥胖发生率较低。 | 刘莉 叶鹏 Yatsuya H Li Y Hilawe EH Ota A Wang C Chiang C Zhang Y Uemura M Osako A Ozaki Y Aoyama A Circ J | 2014 | 中华高血压杂志2014，22，12： | 8 |
| 3 | New method for polymer electrolyte fuel cells显示文摘 | UCHIDA M AOYAMA Y EDA N | 1995 | J Electrochem Soc1995，142，2： | 2 |
| 4 | The dialectics of geographic and virtual space 显示文摘 | Aoyama Y Sheppard E | 2003 | Environment and Planning A2003，35，7： | 1 |
| 5 | 查看详情显示文摘 | Qian W Ishihara A Aoyama Y Kabe T | | 0，，： | 1 |
| 6 | Multiple popu- lation structure of the giant mottled eel, Anguilla mar- morata 显示文摘 | Minegishi Y Aoyama J Tsukamoto K | 2008 | Molecular Ecology2008，7，3： | 1 |
| 7 | Effect of H2S on hydrodesulfurization of dibenzothiophene and 4,6- dimethydibenzothiophene on a alumina-supported NiMo and NiW catalysts显示文摘 | KABE T AOYAMA Y WANGD | 2001 | Appl Catah A2001，209，： | 1 |
| 8 | Development status of a SiC-foam based flow channel insert for a US-ITER DCLL TBM显示文摘 | Sharafat S Aoyama A Morley N Smolentsev S Katoh Y Williams B Ghoniem N | 2009 | Fusion Science and Technology2009，56，2： | 1 |
| 9 | Three -dimensionalanalysis of ribonueleoprotein complexes in influenza A virus 显示文摘 | Noda T Sugita Y Aoyama K | 2012 | Nat Commun2012，3，： | 1 |
| 10 | Heat testing of a prototypical SiC-foam-based flow channel insert显示文摘 | Sharafat S Aoyama A Ghoniem N Williams B Katoh Y | 2010 | Plasma Science IEEE Transactions on2010，38，10： | 1 |
| 11 | Levofloxacin baded triple therapy as a second-line treatment after failure of Helicobacter pylori eradication with standard triple therapy 显示文摘 | Watanabe Y Aoyama N Shirasaka D | 2003 | Dig Liver Dis2003，35，10： | 1 |
| 12 | Augmented expression of cardiotrophin-1 and its receptor component, gp130, in both left and right ventricles after myocardial infarction in the Rat显示文摘 | Aoyama T Takimoto Y Pennica D | 2000 | J Mol Cell Cardiol2000，32，： | 1 |
| 13 | Virulence of Pseudomonas aeruginosa and Spontaneous Spread of Pseudomonas Pneumonia in a Mink Ranch 显示文摘 | Shimizu T Homma J Y Aoyama T | 1974 | Infection and Immunity1974，10，1： | 1 |
| 14 | A novel disease with deficiency of mitochondrial very-long-chain acyl-CoA dehydrogenase 显示文摘 | Aoyama T Uchida Y Kelley R I Marble M | 1993 | Biochem Biophys Res Commun1993，191，： | 1 |
| 15 | Growth of Adhesive c-BN Films on a Tensile BN Buffer Layer显示文摘 | Y K Yap T Aoyama Y Wada | 2000 | Diamond Relat Mate2000，36，9： | 1 |
| 16 | Archives of Biochemistry and Biophysics显示文摘 | Ogra Y Aoyama M Suzuki K T | 2006 | 451 (2) : 1122006，451，2： | 1 |
| 17 | Cell-permeable artificial zinc- finger proteins as potent antiviral drugs for human papillomaviruses 显示文摘 | Mino T Mori T Aoyama Y | 2008 | Arch Viro12008，153，7： | 1 |
| 18 | Solvent-free synthesis of 2-aryl and 2-alkylbenzothiazoles on silica gel under microwave irradiation显示文摘 | KODOMARI TAMARU M AOYAMA Y T | 2004 | Synth Commun2004，34，16： | 1 |
| 19 | Excessive activation of matrix metalloproteinases coincides with left ventricular remodeling during transition from hypertrophy to heart failure in hypertensive rats显示文摘 | IWANAGA Y AOYAMA T KIHARA Y | 2002 | J Am Coll Cardiol2002，39，： | 1 |
| 20 | Overcoming memory T-cell responses for induction of delayed tolerance in nonhuman primates显示文摘 | Yamada Y Boskovic S Aoyama A | 2012 | Am J Transplant2012，12，2： | 1 |
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