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| 1 | New genes emerging for colorectal cancer predisposition显示文摘Colorectal cancer(CRC)is one of the most frequent neoplasms and an important cause of mortality in the developed world.This cancer is caused by both genetic and environmental factors although 35%of the variation in CRC susceptibility involves inherited genetic differences.Mendelian syndromes account for about5%of the total burden of CRC,with Lynch syndrome and familial adenomatous polyposis the most common forms.Excluding hereditary forms,there is an important fraction of CRC cases that present familial aggregation for the disease with an unknown germline genetic cause.CRC can be also considered as a complex disease taking into account the common diseasecommom variant hypothesis with a polygenic model of inheritance where the genetic components of common complex diseases correspond mostly to variants of low/moderate effect.So far,30 common,low-penetrance susceptibility variants have been identified for CRC.Recently,new sequencing technologies including exomeand whole-genome sequencing have permitted to add a new approach to facilitate the identification of new genes responsible for human disease predisposition.By using whole-genome sequencing,germline mutations in the POLE and POLD1 genes have been found to be responsible for a new form of CRC genetic predisposition called polymerase proofreading-associated polyposis. | Clara Esteban-Jurado Pilar Garre Maria Vila Juan José Lozano Anna Pristoupilova Sergi Beltrán Anna Abulí Jenifer Muoz Francesc Balaguer Teresa Ocaa Antoni Castells Josep M Piqué Angel Carracedo Clara Ruiz-Ponte Xavier Bessa Montserrat Andreu Luis Bujanda Trinidad Caldés Sergi Castellví-Bel | 2014 | World Journal of Gastroenterology2014，20，8： | 3 |
| 2 | Susceptibility Genetic Variants Associated With Colorectal Cancer Risk Correlate With Cancer Phenotype显示文摘 | Anna Abulí Xavier Bessa Juan Ramón González Clara Ruiz–Ponte Alejandro Cáceres Jenifer Mu?oz Victoria Gonzalo Francesc Balaguer Ceres Fernández–Rozadilla Dolors González Luisa de Castro Juan Clofent Luís Bujanda Joaquín Cubiella Josep M a Re?é Juan Diego | 2010 | Gastroenterology2010，，3： | 2 |
| 3 | In vivo anticancer activity of vanillin semicarbazone显示文摘Objective:To evaluate the anticancer activity of vanillin semicarbazone(VSC) against Ehrlich ascites carcinoma(EAC) cells in Swiss albino mice.Methods:The compound VSC at three doses(5, 7.5 and 10 mg/kg i.p.) was administered into the intraperitoneal cavity of the EAC inoculated mice to observe its efficiency by studying the cell growth inhibition, reduction of tumour weight,enhancement of survival time as well as the changes in depleted hematological parameters. Allsuch parameters were also studied with a known standard drug bleomycin at the dose of 0.3 mg/kg(i.p.).Results:Among the doses studied, 10 mg/kg(i.p.) was found to be quite comparable in potency to that of bleomycin at the dose of 0.3 mg/kg(i.p.). The host toxic effects of VSC was found to be negligible.Conclusions:It can be concluded that VSC can therefore be considered as potent anticancer agent. | Shaikh M Mohsin Ali M Abul Kalam Azad Mele Jesmin Shamim Ahsan M Mijanur Rahman Jahan Ara Khanam M Nazrul Islam Sha M Shahan Shahriar | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，6： | 2 |
| 4 | Comparison of digesting capacity of nitric acid and nitric acid-perchloric acid mixture and the effect of lanthanum chloride on potassium measurement显示文摘 | SHAIBUR M R Shamim Abul Hasnat Md | 2010 | Nature and Science2010，8，5： | 1 |
| 5 | Detection of DNA damage by alkaline single cell gel electrophoresis in 2,4-dichlorophenoxyace- tic-acid- and butachlor-exposed erythrocytes of Clarias batrachus显示文摘 | ATEEQ B ABUL F M AHMAD W | 2005 | Ecotoxicology and Environmental Safety2005，62，3： | 1 |
| 6 | Introduction of Micronuclei and Erythrocyte Alterations in the Catfish Clarias Batrachus by 2,4-Dichlorophenoxyacetic Acid and Butachlor Mutation Research Genetic Toxicology显示文摘 | ATEEQ B ABUL F M NIAMAT A M | 2002 | Environmental Mutagenesis2002，518，2： | 1 |
| 7 | Functions of 5- HT2A receptor and its antagonists in the eardiovaseular system 显示文摘 | Nagatomo T Rashid M Abul Muntasir H | 2004 | Pharmaeol Ther2004，104，1： | 1 |
| 8 | Economic Determinants of Foreign Direct Investment in Less Developed Countries 显示文摘 | Shamsuddin Abul F M | 1994 | Paki- stan Development Review1994，，33： | 1 |
| 9 | Anonymization of moving objects databases by clustering and perturbation显示文摘 | Abul O Bonchi F Nanni M | 2010 | Information Sys- tems2010，35，8： | 1 |
| 10 | A Multivariate Cointegrated Modeling Ap-proach in Testing Temporal Causality between Energy Consumption,Real In-come and Prices with an Application to Two Asian LDCs显示文摘 | Abul M M Masih Rumi Masih | 1998 | Applied Eco-nomics1998，30，10： | 1 |
| 11 | Energy Cansurrrptian,Real Income and Tem-poral Causality:Restdte from a Multi-country Study Based on Coimegration and Error-correction Modelling Techniques显示文摘 | Abul M M Masih Rumi Masih | 1996 | Energy Ecanornics1996，18，3： | 1 |
| 12 | A Multivariate Cointegrated Modelling Ap-pRoach in Testing Temporal Causality between Energy Consumption,Real Incane and Prices with an Application to Two Asian LDCs显示文摘 | Abul M M Masih Rumi Masih | 1998 | Applied Eco-nomics1998，30，10： | 1 |
| 13 | BMPR1A mutations in early‐onset colorectal cancer with mismatch repair proficiency显示文摘 | C Fernandez‐Rozadilla A Brea‐Fernández X Bessa C álvarez‐Urturi A Abulí J Clofent A Payá R Jover R Xicola X Llor M Andreu A Castells á Carracedo S Castellví‐Bel C Ruiz‐Ponte | 2013 | Clin Genet2013，，1： | 1 |
| 14 | Dif- ferential expression of follicular fluid cytokines: relationship to subsequent pregnancy in IVF cycles 显示文摘 | BEDAIWY M SHAHIN A Y ABUL HASSAN A M | 2007 | Reprod Biomed Online2007，15，3： | 1 |
| 15 | Criminal poisoning of commuters in Bangladesh: Prospective and retrospective study显示文摘 | Mahbub M Ariful B Abul M | 2008 | Forensic Science International2008，180，1： | 1 |
| 16 | Studies on ambient cured polyurethane modified epoxy coatings synthesized from a sustainable resource 显示文摘 | SHARIF A ABUL H ASHRAF S M | 2002 | Progress in Crystal Growth and Characterization of Materials2002，45，12： | 1 |
| 17 | Synthesis of Dimethyl Derivatives of Imidazoline Herbicides: Their Use in Efficient Gas Chromatographic Methods for the Determination of These Herbicides 显示文摘 | ABUL K M A MOHAMMED A NORLIDA O | 2000 | Journal of Agricultural and Food Chemistry2000，48，12： | 1 |
| 18 | Augmentation of spinal morphine analgesia and inhibition of tolerance by low doses of mu-and delta-opioid receptor antagonists显示文摘 | ABUL HUSN N S SUTAK M MILNE B | 2007 | Br J Pharmacol2007，151，6： | 1 |
| 19 | Fungal phyA gene expressed in potato leaves produces active and stable phytase显示文摘 | Abul H J U Kandan S Edward J M | 2003 | Biocbem Biophys Res Commun2003，306，： | 1 |
| 20 | Improved tolerance to salinity and low temperature in transgenic tobacco producing glycine betaine显示文摘 | KJELL O H SUSANNE S ABUL M | 2000 | Journal of Experimental Botany2000，51，： | 1 |
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