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| 1 | 先进的陆地和海底管道涂覆技术显示文摘油气工业的快速发展给诸如在寒冷的气候和深水环境中、具有独特应用地位的管道涂覆技术的革新带来了巨大的挑战和机遇。突出强调了几种独特的、先进的并已经过证实的管道涂覆技术,这些技术适用于陆地和海底管道的保护,包括高效复合涂层系统(HPCC)、高强度钢粉末涂层低温涂覆技术和Thermotite稳流保证技术。给出了一些案例和收集的技术数据。 | Shiwei William Guan Nick Gritis Adam Jackson Peter Singh | 2005 | 油气储运2005,24,B12: | 11 |
| 2 | 美国国家卒中协会短暂性脑缺血发作处理指南显示文摘目的:短暂性脑缺血发作(TIA)是常见和重要的卒中先兆。其处理方法多样,大多数发表的指南在近年来均未被更新。我们试图制定一个全面的、无偏倚的、循证的TIA处理指南。方法:根据一种客观标准(可以预测在该研究领域中执业医师对专家提名的文献测量学方法)挑选出15名专家组成员。通过系统回顾检索到过去发表的指南,由专家对其中的推荐意见的质量进行独立评价。选择出质量最高的推荐意见,然后让专家组采用改良Delphi法通过多次问卷调查的方式进行修订,从而对新的修改达成共识。给专家们提供近期临床研究的系统评价,要求专家根据新的证据判断措辞修改的合理性并且根据证据等级和质量对最终的推荐意见进行评定。不允许专家在预期有可能存在任何利益冲突的专题方面提出推荐意见。结果:通过系统回顾检索到257个指南,其中有13篇文献包括的137条推荐意见符合所有纳入标准。需要6次重复的问卷调查对53条最终推荐意见的措辞达成共识。最终的推荐意见涉及TIA的初步处理、评价、内科治疗、外科治疗和危险因素控制。结论:对TIA患者医疗诊治的最终推荐意见强调了紧急评价和治疗的重要性。这种用于制定本指南的新方法是可行的,考虑到了快速更新并能减少偏倚。 | S. Claiborne Johnston Mai N. Nguyen-Huynh Miriam E. Schwarz Kate Fuller Christina Williams S. Andrew Josephsort Graeme J. Hankey Robert G. Hart Steven R. Levine Jose Biller Robert D. Brown Ralph L. Sacco L. Jaap Kappelle Peter J. Koudstaal Julien Bogousslavsky Louis R. Caplan Jan van Gijn Ale Algra Peter M. Rothwell Harold P. Adams Gregory W. Albers 李海峰(译) | 2007 | 国际脑血管病杂志2007,15,3: | 5 |
| 3 | High prevalence of epilepsy in two rural onchocerciasis endemic villages in the Mahenge area,Tanzania,after 20 years of community directed treatment with ivermectin显示文摘Background:Epilepsy is a neurological disorder with a multitude of underlying causes,which may include infection with Onchocerca volvulus,the parasitic worm that causes human onchocerciasis.A survey carried out in 1989 revealed a high prevalence of epilepsy(1.02%overall,ranging from 0.51 to 3.71%in ten villages)in the Mahenge area of Ulanga district,an onchocerciasis endemic region in south eastern Tanzania.This study aimed to determine the prevalence and incidence of epilepsy following 20 years of onchocerciasis control through annual community directed treatment with ivermectin(CDTI).Methods:The study was conducted in January 2017 in two suburban and two rural villages in the Mahenge area.Door-todoor household visits were carried out by trained community health workers and data assistants to screen for persons suspected of having epilepsy,using a standardised questionnaire.Persons with suspected epilepsy were then interviewed and examined by a neurologist for case verification.Onchocerciasis associated epilepsy was defined as epilepsy without an obvious cause,with an onset of seizures between the ages of 3-18 years in previously healthy children.In each village,fifty males aged≥20 years were tested for onchocerciasis antibodies using an OV16 rapid test and were examined for presence of onchocerciasis nodules.Children aged 6-10 years were also tested using OV16 tests.Results:5117 individuals(median age 18.5 years,53.2%female)from 1168 households were screened.244(4.8%)were suspected of having epilepsy and invited for neurological assessment.Prevalence of epilepsy was 2.5%,with the rural villages having the highest rate(3.5%vs 1.5%),P<0.001.Overall incidence of epilepsy was 111 cases(95%CI:73-161)per 100000 person-years,while that of onchocerciasis associated epilepsy was 131(95%CI:70-223).Prevalence of OV16 antibodies in adult males and among children 6-10 years old was higher in rural villages than in suburban villages(76.5%vs 50.6,and 42.6%vs 4.7%respectively),(P<0.001),while overall prevalence of onchocerciasis nodules was 1.8%.Conclusions:This survey revealed a high prevalence and incidence of epilepsy in two rural onchocerciasis endemic villages in the Mahenge area.Despite 20 years of CDTI,a high prevalence of OV16 antibodies in children aged 6-10 years suggests on-going O.volvulus transmission.Reasons for the persistence of on-going parasite transmission in the Mahenge area need to be investigated. | Bruno P.Mmbando Patrick Suykerbuyk Mohamed Mnacho Advocatus Kakorozya William Matuja Adam Hendy Helena Greter Williams H.Makunde Robert Colebunders | 2018 | Infectious Diseases of Poverty2018,7,1: | 4 |
| 4 | Signalization options to improve capacity and delay at roundabouts through microsimulation approach:A case study on arterial roadways in Ghana显示文摘Roundabouts are very useful when flows are balanced but can have operational challenges when flows increase.Most roundabouts on arterial roadways in Ghana experience recurring congestion during peak traffic.The four roundabouts between Ejisu Municipality and Asokwa Municipality on the N6 highway are typical of the situation found on arterials countrywide.They experience recurring long queues and delays during the peak hours and over-representation of truck rollover accidents.In Ghana,historically,most roundabouts with capacity problems have been developed into interchanges at very high cost without consideration of other effective at-grade configurations.When roundabouts are signalized,various configurations can be explored to enhance capacity while preserving the safety benefits.Using simulation techniques,various configurations and design options were tested for their effectiveness at two of the roundabouts,located at KNUST police station and Ejisu,with similar demand and high left turning volumes.The objectives of this study were to a)evaluate the performance of the selected roundabouts on the corridor;b)explore alternative intersection configurations to improve capacity and delay.Using video data collection techniques,2-h time stamped footages of AM and PM peak traffic flows were captured for two days.Geometric design parameters of the existing roundabouts,queue lengths,travel times,and approach flows were also captured.VISSIM models of the selected roundabouts were developed and calibrated for the baseline conditions.Signalized unconventional roundabout configuration,with a phase for major road through traffic were simulated and assessed for capacity,delay and queue length.The results showed that signalized roundabout intersections effectively increased capacity by as much as 50%in some cases,reduced delay and queue length significantly,and maintained the benefits of roundabouts including safety.The performance could be further enhanced by introducing separate left turn phases to reduce conflicts or through a right turn U-turn(RTUT)concept. | Kwame Kwakwa Osei Charles Anum Adams Williams Ackaah Yolanda Oliver-Commey | 2021 | Journal of Traffic and Transportation Engineering(English Edition)2021,8,1: | 3 |
| 5 | Impact of Stone Location on Success Rates of Endoscopic Lithotripsy for Nephrolithiasis显示文摘 | Adam E. Perlmutter Can Talug William F. Tarry Stanley Zaslau Hesam Mohseni Stanley J. Kandzari | 2008 | Urology2008,,: | 3 |
| 6 | Ischemic and hypoxic preconditioning protect cardiac muscles via intracellular ROS signaling显示文摘氧化应力能在灌注条件下面引起广泛的损坏到心脏的织物。然而, preconditioning 心肌层可以减少这些否定效果并且减轻灌注损害。有许多 preconditioning 治疗,例如 ischemic preconditioning (欧洲电脑生产厂商) 和 hypoxic preconditioning (HPC ) ,指向特定的隧道的各个,受体,或细胞内部的分子。Ischemic preconditioning 包含灌注的简短经期跟随的局部缺血的简短经期,因此为局部缺血的更长的经期加强心脏的抵抗。欧洲电脑生产厂商包含复杂机制,其中一些今天仍然不完全被理解。不过,许多研究已经建立了欧洲电脑生产厂商的模型。另外,类似于欧洲电脑生产厂商, HPC 也作为阻止灌注损害被认出了。反应的氧种类(ROS ) 是欧洲电脑生产厂商和 HPC 的已知的调停人。特别地,产生线粒体的 ROS 开始几条有益的 preconditioning 小径的活动。ROS 的角色是矛盾的;ROS 的底层是在表明 IPC/HPC 的关键因素,但是 ROS 的高水平能在 cardiomyocytes 上贡献增加的氧化应力。因此,决定欧洲电脑生产厂商和 HPC 的分子的机制避免 ROS 的过多的累积阻止心脏的损害是重要的。在这评论,我们将构画出欧洲电脑生产厂商和 HPC,解释在两条小径的 ROS 的通常认为的角色。我们将也处于象锻练那样的某些条件讨论 preconditioning 功效并且变老的心肌层怎么对 preconditioning 治疗作出回应。 | Li ZUO William J. ROBERTS Rosa C. TOLOMELLO Adam T. GOINS | 2013 | Frontiers in Biology2013,8,3: | 3 |
| 7 | Needle-knife sphincterotomy: factors predicting its use and the relationship with post-ERCP pancreatitis (with video)显示文摘 | Adam A. Bailey Michael J. Bourke Arthur J. Kaffes Karen Byth Eric Y. Lee Stephen J. Williams | 2010 | Gastrointestinal Endoscopy2010,,2: | 2 |
| 8 | Measurements of Acute Cerebral Infarction: A Clinical Examination Scale显示文摘 | Thomas Brott Harold P. Adams Charles P. Olinger John R. Marler William G. Barsan José Biller Judith Spilker Renee Holleran Robert Eberle Vicki Hertzberg Marvin Rorick Charles J. Moomaw Michael Walker | 1989 | Stroke1989,,7: | 2 |
| 9 | 2012 ACCF/AHA Focused Update Incorporated Into the ACCF/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction显示文摘 | Jeffrey L. Anderson Cynthia D. Adams Elliott M. Antman Charles R. Bridges Robert M. Califf Donald E. Casey William E. Chavey Francis M. Fesmire Judith S. Hochman Thomas N. Levin A. Michael Lincoff Eric D. Peterson Pierre Theroux Nanette K. Wenger R. Scott | 2013 | Journal of the American College of Cardiology2013,,23: | 2 |
| 10 | Target coverage for head and neck cancers treated with IMRT: review of clinical experiences显示文摘 | Adam S Garden William H Morrison David I Rosenthal K.S.Clifford Chao K.Kian Ang | 2004 | Seminars in Radiation Oncology2004,,: | 2 |
| 11 | EMR of large, sessile, sporadic nonampullary duodenal adenomas: technical aspects and long-term outcome (with videos)显示文摘 | Sina Alexander Michael J. Bourke Stephen J. Williams Adam Bailey Jonard Co | 2009 | Gastrointestinal Endoscopy2009,,1: | 2 |
| 12 | Impaired swallowing mechanics of post radiation therapy head and neck cancer patients: A retrospective videofluoroscopic study显示文摘AIM: To determine swallowing outcomes and hyolaryngeal mechanics associated with post radiation therapy head and neck cancer(rt HNC) patients using videofluoroscopic swallow studies. METHODS: In this retrospective cohort study, video-fluoroscopic images of rt HNC patients(n = 21) were compared with age and gender matched controls(n = 21). Penetration-aspiration of the bolus and bolus residue were measured as swallowing outcome variables. Timing and displacement measurements of the anterior and posterior muscular slings elevating the hyolaryngeal complex were acquired. Coordinate data of anatomical landmarks mapping the action of the anterior muscles(suprahyoid muscles) and posterior muscles(long pharyngeal muscles) were used to calculate the distance measurements, and slice numbers were used to calculate time intervals. Canonical variate analysis with post-hoc discriminant function analysis was performed on coordinate data to determine multivariate mechanics of swallowing associated with treatment. Pharyngeal constriction ratio(PCR) was also measured to determine if weak pharyngeal constriction is associated with post radiation therapy.RESULTS: The rt HNC group was characterized by poor swallowing outcomes compared to the control group in regards to: Penetration-aspiration scale(P < 0.0001), normalized residue ratio scale(NRRS) for the valleculae(P = 0.002) and NRRS for the piriform sinuses(P = 0.003). Timing and distance measurements of the anterior muscular sling were not significantly different in the two groups, whereas for the PMS time of displacement was abbreviated(P = 0.002) and distance of excursion was reduced(P = 0.02) in the rt HNC group. A canonical variate analysis shows a significant reduction in pharyngeal mechanics in the rt HNC group(P < 0.0001). The PCR was significantly higher in the test group than the control group(P = 0.0001) indicating reduced efficiency in pharyngeal clearance. CONCLUSION: Using videofluoroscopy, this study shows rt HNC patients have worse swallowing outcomes associated with reduced hyolaryngeal mechanics and pharyngeal constriction compared with controls. | William G Pearson Jr Alisa A Davidoff Zachary M Smith Dorothy E Adams Susan E Langmore | 2016 | World Journal of Radiology2016,8,2: | 2 |
| 13 | The effect of endoscopic sphincterotomy on acute and chronic complications of biliary endoprostheses显示文摘 | Craig Margulies Eduardo Sampaio Siqueira William Bruce Silverman Xue Sen Lin John Anthony Martin Mordechai Rabinovitz Adam Slivka | 1999 | Gastrointestinal Endoscopy1999,,6: | 2 |
| 14 | Whole brain radiation therapy with or without stereotactic radiosurgery boost for patients with one to three brain metastases: phase III results of the RTOG 9508 randomised trial显示文摘 | David W Andrews Charles B Scott Paul W Sperduto Adam E Flanders Laurie E Gaspar Michael C Schell Maria Werner-Wasik William Demas Janice Ryu Jean-Paul Bahary Luis Souhami Marvin Rotman Minesh P Mehta Walter J Curran | 2004 | The Lancet . 2004 (9422)2004,,9422: | 2 |
| 15 | Survival after inflammatory bowel disease-associated colorectal cancer in the Colon Cancer Family Registry显示文摘AIM: To investigate the survival of individuals with colorectal cancer (CRC) with inflammatory bowel disease (IBD-associated CRC) compared to that of individuals without IBD diagnosed with CRC. METHODS: Epidemiologic, clinical, and follow-up data were obtained from the Colon Cancer Family Registry (Colon CFR). IBD-associated cases were identified from self-report of physician diagnosis. For a subset of participants, medical records were examined to confirm self-report of IBD. Cox proportional hazards regression was applied to estimate adjusted hazard ratios (aHR) and 95%CI of mortality, comparing IBD-associated to non-IBD-associated CRC, adjusted for age at CRC diagnosis, sex, Colon CFR phase, and number of prior endoscopies. Following imputation to complete CRC stage information, adjustment for CRC stage was examined. RESULTS: A total of 7202 CRC cases, including 250 cases of IBD-associated CRC, were analyzed. Over a twelve year follow-up period following CRC diagnosis, 2013 and 74 deaths occurred among non-IBD associated CRC and IBD-associated CRC patients, respectively. The difference in survival between IBD-associated and non-IBD CRC cases was not statistically significant (aHR = 1.08; 95%CI: 0.85-1.36). However, the assumption of proportional hazards necessary for valid inference from Cox regression was not met over the entire follow-up period, and we therefore limited analyses to within five years after CRC diagnosis when the assumption of proportional hazards was met. Over this period, there was evidence of worse prognosis for IBD-associated CRC (aHR = 1.36; 95%CI: 1.05-1.76). Results were similar when adjusted for CRC stage, or restricted to IBD confirmed in medical records. CONCLUSION: These results support the hypothesis that IBD-associated CRC has a worse prognosis than non-IBD-associated CRC. | Scott V Adams Dennis J Ahnen John A Baron Peter T Campbell Steven Gallinger William M Grady Loic LeMarchand Noralane M Lindor John D Potter Polly A Newcomb | 2013 | World Journal of Gastroenterology2013,19,21: | 2 |
| 16 | The Influence of Total Nodes Examined, Number of Positive Nodes, and Lymph Node Ratio on Survival After Surgical Resection and Adjuvant Chemoradiation for Pancreatic Cancer: A Secondary Analysis of RTOG 9704显示文摘 | Timothy N. Showalter Kathryn A. Winter Adam C. Berger William F. Regine Ross A. Abrams Howard Safran John P. Hoffman Al B. Benson John S. MacDonald Christopher G. Willett | 2011 | International Journal of Radiation Oncology Biology Physics2011,,5: | 2 |
| 17 | Characteristics and outcomes of patients hospitalized for heart failure in the United States: Rationale, design, and preliminary observations from the first 100,000 cases in the Acute Decompensated Heart Failure National Registry (ADHERE)显示文摘 | Kirkwood F. Adams Gregg C. Fonarow Charles L. Emerman Thierry H. LeJemtel Maria Rosa Costanzo William T. Abraham Robert L. Berkowitz Marie Galvao Darlene P. Horton | 2005 | American Heart Journal2005,,2: | 2 |
| 18 | The role of xanthophyll cycle carotenoids in the protection of photosynthesis显示文摘 | Barbara Demmig-Adams William W. Adams | 1996 | Trends in Plant Science1996,,1: | 2 |
| 19 | Enhanced Effect of Combining Human Cardiac Stem Cells and Bone Marrow Mesenchymal Stem Cells to Reduce Infarct Size and to Restore Cardiac Function After Myocardial Infarction显示文摘 | Adam R. Williams Konstantinos E. Hatzistergos Benjamin Addicott Fred McCall Decio Carvalho Viky Suncion Azorides R. Morales Jose Da Silva Mark A. Sussman Alan W. Heldman Joshua M. Hare | 2013 | Circulation2013,,2: | 2 |
| 20 | Adipocyte iron regulates adiponectin and insulin sensitivity显示文摘 | Gabrielsen J Scott Gao Yan Simcox Judith A Huang Jingyu Thorup David Jones Deborah Cooksey Robert C Gabrielsen David Adams Ted D Hunt Steven C Hopkins Paul N Cefalu William T McClain Donald A | 2012 | EN2012,,10: | 2 |