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| 1 | Perioperative blood transfusion decreases long-term survival in pediatric living donor liver transplantation显示文摘BACKGROUND The impact of perioperative blood transfusion on short-and long-term outcomes in pediatric living donor liver transplantation(PLDLT)must still be ascertained,mainly among young children.Clinical and surgical postoperative complications related to perioperative blood transfusion are well described up to three months after adult liver transplantation.AIM To determine whether transfusion is associated with early and late postoperative complications and mortality in small patients undergoing PLDLT.METHODS We evaluated the effects of perioperative transfusion on postoperative complications in recipients up to 20 kg of body weight,submitted to PLDLT.A total of 240 patients were retrospectively allocated into two groups according to postoperative complications:Minor complications(n=109)and major complications(n=131).Multiple logistic regression analysis identified the volume of perioperative packed red blood cells(RBC)transfusion as the only independent risk factor for major postoperative complications.The receiver operating characteristic curve was drawn to identify the optimal volume of the perioperative RBC transfusion related to the presence of major postoperative complications,defining a cutoff point of 27.5 mL/kg.Subsequently,patients were reallocated to a low-volume transfusion group(LTr;n=103,RBC≤27.5 mL/kg)and a high-volume transfusion group(HTr;n=137,RBC>27.5 mL/kg)so that the outcome could be analyzed.RESULTS High-volume transfusion was associated with an increased number of major complications and mortality during hospitalization up to a 10-year follow-up period.During a short-term period,the HTr showed an increase in major infectious,cardiovascular,respiratory,and bleeding complications,with a decrease in rejection complications compared to the LTr.Over a long-term period,the HTr showed an increase in major infectious,cardiovascular,respiratory,and minor neoplastic complications,with a decrease in rejection complications.Additionally,Cox hazard regression found that high-volume RBC transfusion increased the mortality risk by 3.031-fold compared to low-volume transfusion.The Kaplan-Meier survival curves of the studied groups were compared using log-rank tests and the analysis showed significantly decreased graft survival,but with no impact in patient survival related to major complications.On the other hand,there was a significant decrease in both graft and patient survival,with high-volume RBC transfusion.CONCLUSION Transfusion of RBC volume higher than 27.5 mL/kg during the perioperative period is associated with a significant increase in short-and long-term postoperative morbidity and mortality after PLDLT. | Karina Gordon Estela Regina Ramos Figueira Joel Avancini Rocha-Filho Luiz Antonio Mondadori Eduardo Henrique Giroud Joaquim Joao Seda-Neto Eduardo Antunes da Fonseca Renata Pereira Sustovitch Pugliese Agustin Moscoso Vintimilla Jose Otavio Costa Auler Jr Maria Jose Carvalho Carmona Luiz Augusto Carneiro D'Alburquerque | 2021 | World Journal of Gastroenterology2021，27，12： | 6 |
| 2 | Stable femtosecond X-rays with tunable polarization from a laser-driven accelerator显示文摘Technology based on high-peak-power lasers has the potential to provide compact and intense radiation sources for a wide range of innovative applications.In particular,electrons that are accelerated in the wakefield of an intense laser pulse oscillate around the propagation axis and emit X-rays.This betatron source,which essentially reproduces the principle of a synchrotron at the millimeter scale,provides bright radiation with femtosecond duration and high spatial coherence.However,despite its unique features,the usability of the betatron source has been constrained by its poor control and stability.In this article,we demonstrate the reliable production of X-ray beams with tunable polarization.Using ionization-induced injection in a gas mixture,the orbits of the relativistic electrons emitting the radiation are reproducible and controlled.We observe that both the signal and beam profile fluctuations are significantly reduced and that the beam pointing varies by less than a tenth of the beam divergence.The polarization ratio reaches 80%,and the polarization axis can easily be rotated.We anticipate a broad impact of the source,as its unprecedented performance opens the way for new applications. | Andreas Döpp Benoit Mahieu Agustin Lifschitz Cedric Thaury Antoine Doche Emilien Guillaume Gabriele Grittani Olle Lundh Martin Hansson Julien Gautier Michaela Kozlova Jean Philippe Goddet Pascal Rousseau Amar Tafzi Victor Malka Antoine Rousse Sebastien Corde Kim Ta Phuoc | 2017 | Light(Science & Applications)2017，6，1： | 2 |
| 3 | Color match of machinable lithium disillcate ceramics:Effects of cement color and thickness显示文摘 | Niu E Agustin M Douglas R D | 2014 | The Journal of prosthetic dentistry2014，111，1： | 1 |
| 4 | Synthesis, characterization and study of the chromogenic properties of the hybrid polyoxo- metalates 3- ( R = Et, ( cn2 )ncn = CH2 ( n -- 0, 1,4 ), CH2CH2SiEh, CH2CH2SiMe2Ph ) 显示文摘 | Agustin D Dallety J Coelho C | 2007 | J Organometallic Chem2007，692，4： | 1 |
| 5 | Chemische studien über die opiums显示文摘 | AGUSTIN D RIMA G GORNITZKA H | 2000 | Eur J Inorg Chem2000，，4： | 1 |
| 6 | Wheat nitrogen use efficiency in a bed planting system in Northwest Mexico显示文摘 | Agustin Limon-Ortega Kenneth D Sayre | 2000 | Agronomy Journal2000，92，2： | 1 |
| 7 | Mutation of atranscription factor,TFCP2L3,causes progressive au-tosomal dominant hearing loss,DFNA28显示文摘 | Peters L M Anderson D W Griffith A J Grundfast KM San Agustin T B Madeo A C | 2002 | Hum MolGenet2002，11，： | 1 |
| 8 | Design and control strategies of PV-diesel systems using genetic algorithms显示文摘 | LOPEZ R D AGUSTIN J L B | 2005 | Solar Energy2005，，79： | 1 |
| 9 | Clinical and neuropatholgical characteristics of hippocampal sclerosis:a carmntnitybased study显示文摘 | Leverenz JB Agustin CM Tsuang D | 2002 | Arch Neural2002，59，7： | 1 |
| 10 | Straw managemen,croprotation,and nitrogen source effect on wheat grain yield and nitrogen use efficiency显示文摘 | Agustin L O Bram G Kenneth D S | 2008 | European Journal of Agronomy2008，29，1： | 1 |
| 11 | Wheat nitrogen use efficiency in a bed planting system innorthwest Mexico显示文摘 | Agustin Limon-Ortega Kenneth D Sayre Charles A Francis | 2000 | Agronomy Journal2000，92，： | 1 |
| 12 | Clinical and neuropatholgical characteristics of hippocampal sclerosis: a carmntnity-based study 显示文摘 | Leverenz JB Agustin CM Tsuang D | 2002 | Arch Neural2002，59，7： | 1 |
| 13 | Proximal isovelocitysurface area by single-beat three-dimensional color Dopplerechocardiography applied for tricuspid regurgitation quantification显示文摘 | de Agustin JA Viliani D Vieira C | 2013 | J Am Soc Echocardiogr2013，26，： | 1 |
| 14 | Oxobridged bis oxo-vanadium (V) complexes with tridentate Schiff base ligands (VOL)(2)0 (L = SAEI SAMP, SAP): Synthesis, structure and epoxidation catalysis un-der solvent-free conditions 显示文摘 | CORDELLE C AGUSTIN D DARAN J C | 2010 | Inorg Chim Acta2010，364，1： | 1 |
| 15 | Transition metal complexes of(Schiff base)divalent group 14 element species n=M'(CO)6-n(n=1,2,M=Ge,Sn,Pb,M'=Cr,W)显示文摘 | AGUSTIN D RIMA G GORNITZKA H | 2000 | Eur J Inorg Chem2000，，： | 1 |
| 16 | Phenanthrene degradation by microorganisms isolated from a contaminated stream 显示文摘 | Muncnerova D J Agustin | | Bioresour Technol0，48，1： | 1 |
| 17 | Collembola as altema-tive prey sustaining spiders in arable ecosystems: prey detection with-in predators using molecular markers 显示文摘 | AgustiN Shayler S P Harwood J D | 2003 | Molecular Ecology2003，12，12： | 1 |
| 18 | Effects of sa-linity on electrolyte levels (Na, K, and C1- ) in the hemolymph of the Pacific whiteshrimp Litopenaeus vannamei 显示文摘 | AFREDO M H AGUSTIN L C FERNANDO D H | 2010 | Dyn Bio- chem Process Biotechnol Mol Biol2010，5，5： | 1 |
| 19 | Clinical and neuropatholgical characteristics of hippocampal sclerosis: a carmntnity-based study 显示文摘 | Leverenz JB Agustin CM Tsuang D | 2002 | Arch Neural2002，59，7： | 1 |
| 20 | Wheat nitrogen use efficiency in a bed planting system in north- west Mexico显示文摘 | Agustin Limon-Ortega Kenneth D Sayre Charles A Francis | 2000 | A4gron J2000，92，： | 1 |
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