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| 1 | 氮素改变辣椒初级代谢和薄壁组织厚度调控比叶面积研究显示文摘比叶面积(SLA)是影响植物光截获和光利用效率的关键性状,常常影响植物的生长和产量。SLA是解释不同植物在不同环境下生长差异的一个关键性状。光照和氮素供应都是决定SLA的重要因素。为了更好地了解辐照度和氮素对辣椒(Capsicum chinense)SLA的影响,研究对两个中国辣椒商品种(Biquinho和Habanero)的初级代谢产物和形态特征进行了分析。两种基因型辣椒的SLA随着遮阴而增加,但随氮供应量的增加而下降;在氮素供应由缺乏到充足的范围内Habanero品种的SLA表现稳定。相关分析表明,高氮供应导致SLA降低是因为氨基酸、蛋白质和淀粉含量的调节,从而影响叶片密度。此外,在中度缺氮到充足供氮范围内,两种基因型辣椒的SLA表现出响应差异,Biquinho和Habanero分别在栅栏和海绵状薄壁组织上表现出差异。总之,结果表明,SLA对氮供应的反应是由某些代谢物含量和依赖于基因型的影响叶片厚度及密度的薄壁组织变化平衡调节的。 | Lucas de ávila Silva Rebeca P.Omena-Garcia Jorge A.Condori-Apfata Paulo Mafra de Almeida Costa Natália Machado Silva Fábio M.Da Matta Agustin Zsogon Wagner L.Araújo Edgard A.de Toledo Picoli Ronan Sulpice Adriano Nunes-Nesi 沈凌峰 吉雪花(译) | 2021 | 辣椒杂志2021，，3： | 2 |
| 2 | A human ESC model for MLL-AF4 leukemic fusion gene reveals an impaired early hematopoietic-endothelial specification显示文摘MLL-AF4 熔化基因是在在婴儿的高风险的尖锐成淋巴细胞的白血病的一个特点 genomic 错误。尽管 MLL-AF4 在人的开发期间出生前地产生,这很好被建立,它在在 utero 的造血的开发的效果仍然保持未经勘探。我们创造了一个人特定的细胞的系统在 MLL-AF4-expressing 人的胚胎的干细胞(hESCs ) 学习早 hemato-endothelial 开发。介绍的功能的研究,同种细胞的分析和基因表示表明在 hESCs 的 MLL-AF4 的那表情有 phenotypic,功能并且基因表示影响。MLL-AF4 在 hESCs 充当全球 transcriptional 使活跃之物和 homeobox 基因表示的一个积极管理者。机能上地, MLL-AF4 从 hESCs 提高 hemogenic 先锋的说明,但是强烈损害进一步造血的承诺赞成 endothelial 房间命运。MLL-AF4 hESCs transcriptionally 被告知向对 endothelial 成熟敏感的 hemogenic 先锋区分,由联系到 vascular-endothelial 功能和早造血作用的主人基因的显著 upregulation 思考了。而且,我们报导那 MLL-AF4 表情不是足够的转变导出 hESC 的造血的房间。这个工作说明 hESCs 怎么可以提供唯一的卓见进人的开发并且推进我们理解白血病的熔化基因,知道出生前地产生,调整人的胚胎的造血的说明。 | Clara Bueno Rosa Montes Gustavo J Melen Verdnica Ramos-Mejia Pedro J Real Ver6nica Ayllo'n Laura Sanchez Gertmdis Ligero Inmaculada Gutierrez-Aranda Agustin F Femfindez Mario F Fraga Inmaculada Moreno-Gimeno Deborah Btlrks Maria del Carmen Plaza-Calonge Juan C Rodriguez-Manzaneque Pablo Menendez | 2012 | Cell Research2012，22，6： | 2 |
| 3 | Epithelial tumors of the ovary (report of 164 cases) 显示文摘 | De Agustin PP Colina F Martinez TFJ | 1977 | Acta Obstet Ginecol Hisp Lusit1977，25，： | 1 |
| 4 | Pd and Pt catalysts supported on carbon-coated monoliths for low-temperature combustion of xylenes显示文摘 | Agustin F Perez-Cadenas Freek Kapteijn Jacob A Moulijn | 2006 | Carbon2006，44，12： | 1 |
| 5 | Conservative management of patients with early endometrial carcinoma : a systematic review 显示文摘 | Chiva de Agustin L Lapuente Sastre F Corraliza Galan V | 2008 | Clin Transl Oncol2008，10，3： | 1 |
| 6 | Tuning the morphology of monolith coatings显示文摘 | Agustin F Perez Cadenas Freek Kapteijn | 2007 | Applied Catalysis A2007，319，： | 1 |
| 7 | Glottal source biometricalsignature for voice pathology detection显示文摘 | PEDRO G V ROBERTO F B VICTORIA R B VICTOR N L AGUSTIN A M LUIS M M F RAFAEL M O JUAN I G L | 2009 | Speech Communication2009，51，9： | 1 |
| 8 | Colorectal Cancer:Epidemiology,Risk Factors,and Health Services显示文摘 | Amersi F Agustin M Ko C Y | 2005 | Clin Colon Rectal Surg2005，18，3： | 1 |
| 9 | Deletion of the M5 musearinic acetylcholine receptor attenuates morphine reinforcement and withdrawal but not morphine analgesia 显示文摘 | Basile AS Irina F Agustin Z | 2002 | Proc Natl Acad Sci USA2002，99，11： | 1 |
| 10 | Colorectal cancer: epide- miology, risk factors, and health services显示文摘 | Amersi F Agustin M Ko CY | 2005 | Clin Colon Rectal Surg2005，18，3： | 1 |
| 11 | Vaccination against Taenia solium cysticercosis in pigs using native and recombinant oncosphere antigens 显示文摘 | Agustin P Ana F Charles G G | 1999 | International Journal for Parasiology1999，，29： | 1 |
| 12 | Accelerated ripening of Manchego type cheese by added commercial enzyme preparation from Aspergillus oryzae显示文摘 | ESTRELLA F G AGUSTIN O DOLORES C | 1993 | Enzyme and Microbial Technology1993，15，： | 1 |
| 13 | Differences in AMPK ex- pression between subcutaneous and visceral adipose tissue in morbid obesity显示文摘 | Martinez Agustin O Herngndez Morante J J Martinez Plata E Sfinchez de Medina F Oaraulet M | 2010 | Regul Pept2010，163，： | 1 |
| 14 | Adapting a measure of acculturation for cross-cultural research显示文摘 | Delacruz F A Padilla G V Agustin E O | 2000 | J Transcult Nurs2000，11，3： | 1 |
| 15 | Accurate subpixel edge location based on partial area effect 显示文摘 | Agustin T P Karl K Miguel A F | 2013 | Image and Vision Computing(S0262-8856)2013，31，1： | 1 |
| 16 | Vaccination against Taenia solium cysticercosis in pig using native and recombinant oncosphere antigens显示文摘 | Agustin P Ana F Charles G G | 1999 | International Journal for Parasitology1999，29，： | 1 |
| 17 | The Golgin GMAP210/TRIP11 anchorslFT20to heGolgicomplex显示文摘 | Follit J A San Agustin J T Xu F | 2008 | PLoS Genet2008，4，10： | 1 |
| 18 | Colorectal Cancer:EpidemiologyRisk Factors,and Health Services显示文摘 | Amersi F Agustin M Ko C Y | 2005 | Clin Colon RectalSurg2005，18，3： | 1 |
| 19 | Vaccination against Taenia solium cysticercosis in pigs using native and recombinant oncosphere antigens显示文摘 | Agustin P Ana F Charles G C | 1999 | Int J Parasiol1999，，29： | 1 |
| 20 | Evaluation of an educational telephone intervention strategy to improve non-screening colonoscopy attendance:A randomized controlled trial显示文摘BACKGROUND Colonoscopy attendance is a key quality parameter in colorectal cancer population screening programmes.Within these programmes,educative interventions with bidirectional contact carried out by trained personnel have been proved to be an important tool for colonoscopy attendance improvement,and because of its huge clinical and economic impact,they have been widely implemented.However,outside of this population programmes,educative measures to improve colonoscopy attendance have been poorly studied and no navigation interventions are usually performed.AIM To investigate the clinical and economic impacts of an educational telephone intervention on colonoscopy attendance outside colorectal cancer screening programmes.METHODS This randomized controlled trial included consecutive patients referred to colonoscopy from primary care centres from November 2017 to May 2018.The intervention group(IG)received a telephone intervention,while the control group(CG)did not.Patients assigned to the IG received an educational telephone call 7 d before the colonoscopy appointment.The intervention was carried out by two nurses with deep endoscopic knowledge who were previously trained for a telephone educational intervention for colonoscopy.The impact on patient compliance with preparedness protocols related to bowel cleansing,antithrombotic management,and sedation scheduling was also evaluated.A second call was conducted to assess patient satisfaction.Intention-to-treat(ITT)and perprotocol(PP)analyses were performed.RESULTS A total of 738 and 746 patients were finally included in the IG and CG respectively.Six hundred thirteen(83%)patients were contacted in the IG.The non-attendance rate was lower in the IG,both in the ITT analysis(IG 8.4%vs CG 14.3%,P<0.001)and in the PP analysis(4.4%vs 14.3%,P<0.001).In a multivariable analysis,belonging to the control group increased the risk of nonattendance in both,the ITT analysis(OR 1.81,95%CI:1.27 to 2.58,P=0.001)and the PP analysis(OR 3.56,95%CI:2.25 to 5.64,P<0.001).There was also a significant difference in compliance with preparedness protocols[bowel cleansing:IG 61.7%vs CG 52.6%(P=0.001),antithrombotic management:IG 92.5%vs CG 62.8%(P=0.001),and sedation scheduling:IG 78.8%vs CG 0%(P≤0.001)].We observed a net benefit of €55600/year after the intervention.The information given before the procedure was rated as excellent by 26%(CG)and 51%(IG)of patients,P≤0.001.CONCLUSION Educational telephone nurse intervention improves attendance,protocol compliance and patient satisfaction in the non-screening colonoscopy setting and has a large economic impact,which supports its imple-mentation and maintenance over time. | Agustin Seoane Xenia Font Juan C Perez Rocio Perez Carlos F Enriquez Miriam Parrilla Faust Riu Josep M Dedeu Luis E Barranco Xavier Duran Ines A Ibanez Marco A Alvarez | 2020 | World Journal of Gastroenterology2020，26，47： | 0 |
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