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| 1 | 尿钠排泄、血压、心血管病与死亡率的关系:社区前瞻性流行病学队列研究显示文摘WHO建议人群钠摄人<2 g/d作为预防心血管病的措施之一,但这一目标在任何国家都没有实现。该建议主要基于短期血压试验的个体水平数据,没有来自随机试验或观察性研究的关于低钠摄入与降低心血管事件的数据。前瞻性城市农村流行病学研究目前正在21个国家进行。该文对其中18个国家的数据进行分析,其中包含了临床结果数据。 | Mente A O'Donnell M Rangarajan S McQueen M Dagenais G Wielgosz A Lear S Ah STL Wei L Diaz R Avezum A Lopez-Jaramillo P Lanas F Mony P Szuba A Iqbal R Yusuf R Mohammadifard N Khatib R Yusoff K Ismail N Gulec S Rosengren A Yusufali A Kruger L Tsolekile LP Chifamba J Dans A Alhabib KF Yeates K Teo K Yusuf S 刘莉 叶鹏 | 2018 | 中华高血压杂志2018，26，12： | 29 |
| 2 | miR-182参与调节胶质母细胞瘤的凋亡、生长和分化(英文)显示文摘Glioblastoma multiforme(GBM)is a lethal,therapy-resistant brain cancer consisting of numerous tumor cell subpopulations,including stem-like glioma-initiating cells(GICs),which contribute to tumor recurrence following initial response to therapy.Here,we identified miR-182 as a regulator of apoptosis,growth,and differentiation programs whose expression level is correlated with GBM patient survival.Repression of Bcl2-like12(Bcl2L12),c-Met,and hypoxia-inducible factor 2α(HIF2A)is of central importance to miR-182 anti-tumor activity,as it results in enhanced therapy susceptibility,decreased GIC sphere size,expansion,and stemness in vitro.To evaluate the tumor-suppressive function of miR-182 in vivo,we synthesized miR-182-based spherical nucleic acids(182-SNAs);i.e.,gold nanoparticles covalently functionalized with mature miR-182 duplexes.Intravenously administered 182-SNAs penetrated the bloodbrain/blood-tumor barriers(BBB/BTB)in orthotopic GBM xenografts and selectively disseminated throughout extravascular glioma parenchyma,causing reduced tumor burden and increased animal survival.Our results indicate that harnessing the anti-tumor activities of miR-182 via safe and robust delivery of 182-SNAs represents a novel strategy for therapeutic intervention in GBM. | Kouri FM Hurley LA Daniel WL Day ES Hua Y Hao L Peng CY Merkel TJ Queisser MA Ritner C Zhang H James CD Sznajder JI Chin L Giljohann DA Kessler JA Peter ME Mirkin CA Stegh AH | 2015 | 中华神经外科疾病研究杂志2015，14，2： | 14 |
| 3 | 茶叶摄入与中国成年人高密度脂蛋白胆固醇浓度纵向变化的关系显示文摘茶叶摄入与高密度脂蛋白胆固醇(high-density lipoprotein cholesterol,HDL-C)浓度的年龄相关变化之间的关系仍不清楚。该研究目的是探索茶摄入量与HDL-C浓度纵向变化之间的关系。研究人员通过调查问卷评估基线(2006年)的茶叶消费量,并在2006、2008、2010和2012年测量了未患有心血管病或癌症. | 刘莉 叶鹏 Huang S Li J Wu Y Ranjbar S Xing A Zhao H Wang Y Shearer GC Bao L Lichtenstein AH Wu S Gao X | 2018 | 中华高血压杂志2018，26，8： | 5 |
| 4 | 低浓度胰岛素样生长因子Ⅱ可以预报正常体重2型糖尿病患者的体重增加显示文摘 | Heald AH Karvestedt L Anderson SG 菅鑫妍 | 2006 | 中国处方药2006，5，6： | 3 |
| 5 | 强化降压治疗期间估算的肾小球滤过率初始降低与长期肾功能:收缩压干预试验与控制糖尿病患者心血管病风险行动研究-血压随机对照试验的事后分析显示文摘血压降低可导致估算的肾小球滤过率(estimated glomerular filtration rate,eGFR)的初始下降,但eGFR降低多少可以接受仍存在争议。研究人员对控制糖尿病心血管病风险行动(action to control cardiovascular risk in diabetes,ACCORD)-血压研究及收缩压干预试验(systolic blood pressure intervention trial,SPRINT)进行事后分析,两项研究均随机将患者分为强化或标准收缩压靶目标治疗。 | 赵狄(译) 刘莉(校) Collard D Brouwer TF Engberink RHGO Zwinderman AH Vogt L Born BJH | 2020 | 中华高血压杂志2020，28，5： | 3 |
| 6 | Physical activity and breast cancer risk among Asian-American women in LosAngeles: a case-control study显示文摘 | Yang D Bernstein L Wu AH | 2003 | Cancer2003，97，107： | 2 |
| 7 | Mitogenicity of the recombinant myco- bacterial 27-kilodalton lipoprotein is not connected to its anti- protective effect 显示文摘 | Hovav AH Davidoviteh L Nussbaum G Mullerad J Fish- man Y Bercovier H | 2004 | Infect Immun2004，72，6： | 1 |
| 8 | HER-2/neu amplification is highly homogenous in gastric cancer 显示文摘 | Marx AH Tharun l Muth J | 2009 | Human Pathology2009，40，6： | 1 |
| 9 | Identification,cloning and expression analysis of the pluripotency promoting Nanog genes in mouse and human显示文摘 | Hart AH Hartley L Ibrahim M | 2004 | Dev Dyn2004，230，1： | 1 |
| 10 | Identification, cloning and expression analysis of the pluripotency promoting nanog genes in mouse and human显示文摘 | Hart AH Hartley L Ibrahin M | 2004 | Dev Dyn2004，230，1： | 1 |
| 11 | Hematologic Toxicity on RTOG 0418: a phase Ⅱ study of post-operative IMRT for gynecologic cancer显示文摘 | Kloppl AH Moughan J Portelance L | 2010 | Int J Radiat Oncol Biol Phys2010，78，3： | 1 |
| 12 | Immune system to brain signaling: neuro- psychopharmacological implications 显示文摘 | Capuron L Miller AH | 2011 | Pharmaeol Ther2011，130，22： | 1 |
| 13 | Expression of connexins 36,43, and 45 during postnatal development of the mouse retina显示文摘 | Kiahara AH Mantovani de Castro L Belmonte MA Yan CY Moriscot AS Hamassald DE | 2006 | J Neurobiol2006，66，13： | 1 |
| 14 | Uptake of the cephalosporin,cephalexin,by a dipeptide transport carrier in the human intestinal cell line,Caco-2显示文摘 | Bergin L | 1990 | Biochem Biophys Acta1990，1027，3： | 1 |
| 15 | Isolation andprimary structure of NGAL,a novel protein associatedwith human neutrophil gelatinase显示文摘 | Kjeldsen L Johsen AH Sengelov | 1993 | J Biol Chem1993，268，10： | 1 |
| 16 | Jun B is required for endothelial cell morphogenesis by regulating core-binding factor beta显示文摘 | Licht AH Pein OT Florin L | 2006 | J Cell Biol2006，175，6： | 1 |
| 17 | The role of a typical organisms in asthma显示文摘 | Daian CM Wolf AH Bielory L et a l | 2002 | Allergy Asthma Proe2002，21，2： | 1 |
| 18 | Improved preoperative definitive diagnosis of papillary thyroid carcinoma in FNAs prepared with both ThinPrep and conventional smears compared with FNAs prepared with ThinPrep alone显示文摘 | Luu MH Fischer AH Pisharodi L | 2011 | Cancer Cytopathol2011，119，1： | 1 |
| 19 | eft atrial appendage closure with the Amplatzer car- diac plug in patients with atrial fibrillation显示文摘 | GUERIOS E E SCHMID M GLOEKLER S et ah l | | Arq Bras Cardiol0，98，： | 1 |
| 20 | Association between in-creased levels of reverse triiodothyronine and mortality after a-cute myocardial infarction显示文摘 | Friberg L Drvota V Bjelak AH’ ef al | 2001 | Am J Med2001，111，9： | 1 |
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