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| 1 | Quality of life assessment in patients with chronic pancreatitis receiving antioxidant therapy显示文摘AIM:To undertake a baseline study comparing quality of life(QoL) in patients with chronic pancreatitis(CP) on Antox to those with CP,matched for disease duration,who were not on this medication.METHODS:CP was defined according to the Zurich classification.Sixty eight consecutive patients with CP who were taking Antox(antioxidants) were compared with 69 consecutive control CP patients not on Antox.European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core questions 30 and Pancreatic Modification(28 questions) were used to assess QoL.Out of a total of 137 patients 28 in each group were matched for disease duration(within 12 mo).Median disease duration was 8(1-22) years in the Antox group and 7(1-23) years in the Non-Antox cohort(P = NS,Mann-Whitney U-test).Other parameters(age,gender,etiology,endocrine and exocrine insufficiency) were similar between groups.RESULTS:Median visual analogue pain score in the Antox group was 3(0-8) compared with 6(0-8) in the Non-Antox group(P < 0.01).Perceptions of cognitive,emotional,social,physical and role function were impaired in the Non-Antox group compared to Antox patients(P < 0.0001,P = 0.0007,P = 0.0032 and P < 0.005 and P < 0.001,respectively).Analgesics and opiate usage was significantly lower in the Antox group(P < 0.01).Overall physical health and global QoL was better in the Antox group(P < 0.0001,95% CI:1.5-3).CONCLUSION:Contemporary quality of life assessments show that after correction for disease duration and cigarette smoking,patients with CP taking antox had better scores than non-antox controls. | Nehal S Shah Alistair J Makin Aali J Sheen Ajith K Siriwardena | 2010 | World Journal of Gastroenterology2010，16，32： | 4 |
| 2 | Cost-effective utilization of single photon emission computed tomography (SPECT)in decision making for epilepsy surgery 显示文摘 | Rathore C Kesavadas C Ajith J | 2011 | Seizure2011，20，： | 1 |
| 3 | Safety, feasibility, and short-term follow-up of drug-eluting stent placement in the intracranial and extracranial circulation显示文摘 | Gupta R AI-Ali F Ajith J | 2006 | Stroke2006，37，10： | 1 |
| 4 | Safety,feasibility,and short-term follow-up of drug-eluting stent placement in the intracranial and extracranial circulation显示文摘 | Firas AA Ajith J | 2006 | Stroke2006，37，： | 1 |
| 5 | D - SCIDS : Distributed soft computing intrusion detection system 显示文摘 | Ajith Abraham Ravi J ain Johnson Thomas | 2007 | Journal of Network and Computer Applications2007，30，1： | 1 |
| 6 | Antimutagenic activity of methanolic extract of Ganoderma lucidum and its effect on he- patic damage caused by benzo pyrene 显示文摘 | Lakshmi B Ajith T A Nayana J | 2006 | J Ethnopharma- co2006，107，2： | 1 |
| 7 | Cost-effective utilization ofsingle photon emission computed tomography(SPECT)in decisionmaking for epilepsy surgery显示文摘 | Rathore C Kesavadas C Ajith J | 2011 | Seizure2011，20，2： | 1 |
| 8 | Progesterone is neuroprotecrive after acute experimental spinal cord trauma in rats显示文摘 | Ajith J Russ P Hiu Q | 1999 | Spine1999，24，20： | 1 |
| 9 | Intrusion detection using an ensemble of intelligent paradigms 显示文摘 | Srinivas Mukkamala Andrew H Sung Ajith Abraham Hochberg J | 2005 | Journal of Network and Computer Applications2005，28，2： | 1 |
| 10 | Spray deposition process of hypereutectic Al-Si alloys显示文摘 | DAYANAND M G RUDRAKSHI G B SRIVASTAV V C JAGANNATH R AJITH G J | 2011 | International Journal of Scientific & Engineering Research2011，6，2： | 1 |
| 11 | Adjuvant therapy for gastric cancer:What have we learned since INT0116?显示文摘Gastric cancer is one of the main cancer-related causes of death worldwide. The curative treatment of gastric cancer consists of tumor resection and lymphadenectomy. However, surgical treatment alone is associated with high recurrence rates. Adjuvant treatment strategies have been studied over the last decades, but there have been controversial results from the initial studies. The pivotal INT0116 study demonstrated that the use of adjuvant chemoradiotherapy with 5-fluorouracil increases relapse-free and overall survival, and it has been adopted across the Western world. The high toxicity of radiochemotherapy and suboptimal surgical treatment employed, with fewer than 10% of the patients submitted to D2 lymphadenectomy, were the main study limitations. Since its publication, other adjuvant treatment modalities have been studied, and radiochemotherapy is being refined to improve its efficacy and safety. A multimodal approach has been demonstrated to significantly increase relapsefree and overall survival, and it can be offered in the form of perioperative chemotherapy, adjuvant chemoradiotherapy or adjuvant chemotherapy, regardless of the extent of lymphadenectomy. The objective of the present review is to report the major advances obtained in the last decades in the adjuvant treatment of gastric cancer as well as the perspectives of treatment based on recent knowledge of the molecular biology of the disease. | Alexandre A Jácome Ajith K Sankarankutty José Sebastiao dos Santos | 2015 | World Journal of Gastroenterology2015，21，13： | 1 |
| 12 | Antimutagenic activity of methanolic exlract of Ganodermalucidum and its effect on hepatic damage caused by benzopyrene显示文摘 | LAKSHMI B AJITH T A NAYANA J | 2006 | J of Ethnopharm2006，19，： | 1 |
| 13 | D-SCIDS: Distributed soft computing intrusion detection system 显示文摘 | AJITH A RAVI J JOHNSON T | 2007 | Journal of Network and Computer Applications2007，30，： | 1 |
| 14 | Study of the patency of different peritoneal drains used prophylactically in bariatric surgery显示文摘AIM:To compare the performance of different types of abdominal drains used in bariatric surgery.METHODS:A vertical banded Roux-en-Y gastric bypass was performed in 33 morbidly obese patients.Drainage of the peritoneal cavity was performed in each case using three different types of drain selected in a randomized manner:a latex tubular drain,a Watterman tubulolaminar drain,and a silicone channeled drain.Drain permeability,contamination of the drained fluid,ease of handling,and patient discomfort were evaluated postoperatively over a period of 7 d.RESULTS:The patients with the silicone channeled drain had larger volumes of drainage compared to patients with tubular and tubulolaminar drains between the third and seventh postoperative days.In addition,a lower incidence of discomfort and of contamination with bacteria of a more pathogenic profile was observed in the patients with the silicone channeled drain.CONCLUSION:The silicone channeled drain was more comfortable and had less chance of occlusion,which is important in the detection of delayed dehiscence. | Wilson Salgado Júnior Marcelo Martins Macedo Neto José Sebastio dos Santos Ajith Kumar Sakarankutty Reginaldo Ceneviva Orlando de Castro e Silva Jr | 2009 | World Journal of Gastroenterology2009，15，19： | 0 |
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