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| 1 | Directly patterned substrate-free plasmonic “nanograter” structures with unusual Fano resonances显示文摘The application of three-dimensional(3D)plasmonic nanostructures as metamaterials(MMs),nano-antennas,and other devices faces challenges in producing metallic nanostructures with easily definable orientations,sophisticated shapes,and smooth surfaces that are operational in the optical regime and beyond.Here,we demonstrate that complex 3D nanostructures can be readily achieved with focused-ion-beam irradiation-induced folding and examine the optical characteristics of plasmonic“nanograter”structures that are composed of free-standing Au films.These 3D nanostructures exhibit interesting 3D hybridization in current flows and exhibit unusual and well-scalable Fano resonances at wavelengths ranging from 1.6 to 6.4 mm.Upon the introduction of liquids of various refractive indices to the structures,a strong dependence of the Fano resonance is observed,with spectral sensitivities of 1400 nm and 2040 nm per refractive index unit under figures of merit of 35.0 and 12.5,respectively,for low-order and high-order resonance in the near-infrared region.This work indicates the exciting,increasing relevance of similarly constructed 3D free-standing nanostructures in the research and development of photonics and MMs. | Ajuan Cui Zhe Liu Jiafang Li Tiehan H Shen Xiaoxiang Xia Zhiyuan Li Zhijie Gong Hongqiang Li Benli Wang Junjie Li Haifang Yang Wuxia Li Changzhi Gu | 2015 | Light(Science & Applications)2015，4，1： | 8 |
| 2 | The Prognostic Significance of a Combined Determination of Cathepsin D and Estrogen Receptors in Breast Carcinomas with Positive Axillary Lymph Nodes显示文摘OBJECTIVE The aim of this study was to investigate the correlation be- tween cathepsin D (Cath-D) and estrogen receptor (ER)expression in breast cancer tissue and to explore the prognostic significance of their combined determination in breast carcinoma patients with positive axillary lymph nodes. METHODS One hundred and thirty-eight cases of breast carcinoma were examined by immunohistochemistry (IHC) and the results relating to patient follow-up analyzed. RESULTS The overall 5 -year disease -free survival rate (DFS) was 60.9% (84/138) in the series. The positive rate of Cath-D expression in the tumor cells was 55.07% and the positive ER staining was 51.4%. A definite significant negative correlation was found between the positive rates for Cath-D and ER (r=-0.294, P=0.001) The Cath-D expression for the cases in clinical Stage II, positive-node and recurrence or distant metastasis, was higher than that those cases in clinical Stage II with fewer node-metastasis and with 5 year DFS (χ2=13.926, P=0.000; χ2= 13.070, P=0.001; χ2=10.545, P=0.001). However, there was no signifi- cant difference of Cath-D expression between 2 groups of patients with different ages or among the different histopathologic types of the non- specific invasive carcinoma. In the combined examination of Cath-D and ER, the cases that were ER (+) and Cath-D (-) had the highest 5-year DFS compared to other situations. In contrast, the cases that were re- versed in expression , ie, ER(-) and Cath-D(+), had a lower 5-year DFS. There was a significant difference between the 2 conditions (χ2=18.675, P=0.000). CONCLUSION A combined determination and analysis of Cath-D and ER expression may be more useful to establish a prognosis than the bio- logical characteristics of carcinomas with positive lymph nodes. | Yun Niu Xue Yang Yu Fan Ajuan Lu Tieju Liu Xilin Fu | 2006 | Chinese Journal of Clinical Oncology2006，3，3： | 2 |
| 3 | Developing radio frequency technology for postharvest insect control in milled rice显示文摘 | Zhou Liyang Ling Bo Zheng Ajuan | | Journal of Stored Products Research0，62，： | 1 |
| 4 | Airflow modelling in a computer room 显示文摘 | aJuan Abanto Daniel Barrero Marcelo Reggio Beno? t Ozell | 2004 | Building and Environment2004，39，12： | 1 |
| 5 | NS codoped carbon nanorods as anode materials for high-performance lithium and sodium ion batteries显示文摘NS codoped carbon nanorods(NS-CNRs) were prepared using crab shell as template and polyphenylene sulfide(PPS) as both the C and S precursor, followed by carbonization in NH_3. The as-obtained NS-CNRs had a diameter of ~50 nm, length of several micrometers, and N and S contents of 12.5 at.% and 3.7 at.%,respectively, which can serve as anodes for both lithium-ion batteries(LIBs) and sodium ion batteries(SIBs). When serving as an anode of LIB, the NS-CNRs delivered gravimetric capacities of 2154 mAh g^(-1)at current densities of 0.1 A g^(-1)and 625 mAh g^(-1)at current densities of 5.0 A g^(-1)for 1000 cycles.When serving as an anode of SIB, the NS-CNRs delivered gravimetric capacities of 303 mAh g^(-1)at current densities of 0.1 A g^(-1)and 230 mAh g^(-1)at current densities of 1.0 A g^(-1)for 3000 cycles. The excellent electrochemical performance of NS-CNRs could be ascribed to the one-dimensional nanometer structure and high level of heteroatom doping. We expect that the obtained NS-CNRs would benefit for the future development of the doped carbon materials for lithium ion batteries and other extended applications such as supercapacitor, catalyst and hydrogen storage. | Ajuan Hu Song Jin Zhenzhen Du Hongchang Jin Hengxing Ji | 2018 | Journal of Energy Chemistry2018，27，1： | 1 |
| 6 | Characteristics of the basement reformed volcanic edifice in Bohai Sea and its implication for hydrocarbon enrichment显示文摘The intact volcanic edifice had been formed and finalized during the depositional stage of Mesozoic Yixian Formation in the Bohai Sea.The residual body of the intact volcanic edifice after reformation was defined as the basement reformed volcanic edifice.Based on drilling,seismic,well logging and microscopic data in the study area,characteristics of the basement reformed volcanic edifice were well discussed,and its control on oil and gas was also investigated.Results showed that the basement reformed volcanic edifice was jointly controlled by magmatic property,paleo-geomorphology and late reformation,and the late fault cutting and differential denudation were major reformation ways of the volcanic edifice;strong and weak volcanic eruption patterns developed in the study belonged to the invertedsequence eruption,and the explosive facies and the intermediate-acidic or acidic effusive facies were the favorable reservoir facies;weathering,cycles and period boundaries controlled vertical distribution of high-quality lithofacies,and coupling between each periodic interface at different levels and residual high-quality lithofacies was the key to oil and gas enrichment.Major exploration targets of volcanic rocks were to find periodic interfaces in the volcanic edifice with the residual high-quality lithofacies within 150 m from the weathering crust or eruption surface. | Tao Ye Ajuan Wei Chunrong Zhu Yuechuan Wang Kunshun Gao Jinchang Zeng | 2017 | Petroleum Research2017，2，4： | 1 |
| 7 | Carbene adduct of cyclopalladated ferrocenylimine as an efficient catalyst for the amination of aryl chlorides显示文摘 | Jingya Li Mengjun Cui Ajuan Yu Yangjie Wu | 2007 | Journal of Organometallic Chemistry2007，，17： | 1 |
| 8 | Palladaeycle-eatalyzed cross-coupling reactions of arylboronic acids with carboxylic anhydrides or acyl chlorides 显示文摘 | Yu Ajuan Shen Lei Cui Xiuling | 2012 | Tetrahedron2012，68，11： | 1 |
| 9 | The concept and realization of nanostructure fabrication using free-standing metallic wires with rapid thermal annealing显示文摘Free-standing metallic nanostructures are considered to be highly relevant to many branches of science and technology with applications of three dimensional metallic nanostructures ranging from optical reflectors,actuators,and antenna,to free-standing electrodes,mechanical,optical,and electrical resonators and sensors.Strain-induced out-of-plane fabrication has emerged as an effective method which uses relaxation of strain-mismatched materials.In this work,we report a study of the thermal annealing-induced shape modification of free-standing nanostructures,which was achieved by introducing compositional or microstructural nonuniformity to the nanowires.In particular gradient,segmented and striped hetero-nanowires were grown by focused-ion-beam-induced chemical vapor deposition,followed by rapid thermal annealing in a N2 atmosphere.Various free-standing nanostructures were produced as a result of the crystalline/grain growth and stress relief. | CUI AJuan HAO TingTing LI Wu Xia SHEN TieHan LIU Zhe JIANG QianQing GU ChangZhi | 2015 | Science China(Physics,Mechanics & Astronomy)2015，58，4： | 0 |
| 10 | Expression of E2F-1, Rb and ER in Peripheral Papil-loma and Ductal Carcinoma in Situ of the Breast and its Significance显示文摘OBJECTIVE To investigate the correlation of E2F-1, Rb and ER expression with peripheral papilloma (Peri-PM) and ductal carcinoma in situ of the breast (DCIS), and further explore some molecular mechanisms of the canceration of Peri-PM. METHODS Imunohistochemistry was used to examine the expression of E2F-1, Rb and ER in 60 Peri-PM, 60 Peri-PM with atypical ductal hyperplasia (Peri-PM with ADH) and 60 DCIS. Normal breast tissues were selected as a control group. RESULTS Based on immunohistochemical staining, the positive rate of E2F-1 expression in Peri-PM, Peri-PM with ADH and DCIS was 21.7%, 46.7% and 78.3% respectively. The positive rate of Rb expression was 83.3 %, 53.9% and 21.7% and the ER expression was 86.7%,61.7% and 55.0%. Significant differences were found among the 3 groups (Peri-PM, Peri-PM with ADH and DCIS) (P<0.05). Significant differences existed between any 2 groups (P<0.05) except for the rate of ER positive expression comparing Peri-PM with ADH verus DCIS (P>0.05). The expression of E2F-1 was nega- tively correlated with ER and Rb, and at the same time the expression of ER was positively correlated with Rb. Following the degree of breast epithelial hyperplasia involved and its development into carcinoma, the positive rate of E2F-1 expression displayed an elevating tendency, but that of Rb and ER expression showed a tendency to decline. CONCLUSION The interaction of the 3 indexes studied may play an im- portant role in the conversion of precancerous lesions to early in situ breast carcinoma, and the evaluation of these indexes might provide a valuable basis for screening high-risk cases of Peri-PM. | Yun Niu Yuxia Gao Xue Yang Yu Li Yong Yu Ajuan Lu | 2007 | Chinese Journal of Clinical Oncology2007，4，4： | 0 |
| 11 | Sinistral strike slip of the Zhangjiakou-Penglai Fault and its control on hydrocarbon accumulation in the northeast of Shaleitian Bulge,Bohai Bay Basin,East China显示文摘The structural style, fault activity, strike-slip displacement, and the formation mechanism and hydrocarbon migration and accumulation in the center tectonic zone in the northeast Shaleitian Bulge of Zhangjiakou-Penglai Fault Zone were studied by seismic attribute analysis, structural geometric analysis, fault activity analysis, structure evolution history and simulation of hydrocarbon migration, based on 3-D seismic and drilling data. The main results are as follows:(1) The study area is a superimposed tectonic zone, which experienced early(Paleocene and Eocene) extension and late(Oligocene and Pliocene-Quaternary) strike-slip and pull-apart.(2) The sinistral strike slip of the northeast Shaleitian Bulge of Zhangjiakou-Penglai Fault Zone went through two periods, Oligocene and Pliocene-Quaternary, and the Bohai section was active earlier than the inland section.(3) The sinistral strike slip displacement of Zhangjiakou-Penglai Fault is 4 km since Cenozoic, including 1 km in the Oligocene, and 3 km in the Pliocene-Quaternary.(4) The strike-slip movements have resulted in the increase of fault activity and basin-mountain restructure in the fault zone, also contributed to the formation of the central tectonic belt and the conjugate evolution in north-east structural belt.(5) The conjugate strike slip of the Zhangjiakou-Penglai Fault Zone dominated the migration and accumulation of hydrocarbon in shallow formations by controlling the injection points and segments of hydrocarbon from the deep layers to shallow layers. | PENG Jingsong WEI Ajuan SUN Zhe CHEN Xinlu ZHAO Dijiang | 2018 | Petroleum Exploration and Development2018，45，2： | 0 |
| 12 | mTORC1 induces plasma membrane depolarization and promotes preosteoblast senescence by regulating the sodium channel Scn1a显示文摘Senescence impairs preosteoblast expansion and differentiation into functional osteoblasts,blunts their responses to bone formation-stimulating factors and stimulates their secretion of osteoclast-activating factors.Due to these adverse effects,preosteoblast senescence is a crucial target for the treatment of age-related bone loss;however,the underlying mechanism remains unclear.We found that mTORC1 accelerated preosteoblast senescence in vitro and in a mouse model.Mechanistically,mTORC1 induced a change in the membrane potential from polarization to depolarization,thus promoting cell senescence by increasing Ca^(2+)influx and activating downstream NFAT/ATF3/p53 signaling.We further identified the sodium channel Scn1a as a mediator of membrane depolarization in senescent preosteoblasts.Scn1a expression was found to be positively regulated by mTORC1 upstream of C/EBPα,whereas its permeability to Na^(+)was found to be gated by protein kinase A(PKA)-induced phosphorylation.Prosenescent stresses increased the permeability of Scn1a to Na^(+)by suppressing PKA activity and induced depolarization in preosteoblasts.Together,our findings identify a novel pathway involving mTORC1,Scn1a expression and gating,plasma membrane depolarization,increased Ca^(2+)influx and NFAT/ATF3/p53 signaling in the regulation of preosteoblast senescence.Pharmaceutical studies of the related pathways and agents might lead to novel potential treatments for agerelated bone loss. | Ajuan Chen Jian Jin Shasha Cheng Zezheng Liu Cheng Yang Qingjing Chen Wenquan Liang Kai Li Dawei Kang Zhicong Ouyang Chenfeng Yao Xiaochun Bai Qingchu Li Dadi Jin Bin Huang | 2022 | Bone Research2022，10，2： | 0 |
| 13 | C30F12.4 influences oogenesis, fat metabolism, and lifespan in C. elegans显示文摘复制,胖新陈代谢,和长寿被缠绕规章的轴;在 C 的最近的研究。elegans 提供了这些过程直接被联合的证据。然而,他们被联合的机制和繁殖信号 modulating 脂肪新陈代谢和 lifespan 糟糕被理解。这里,我们发现那充实卵子发生的基因, c30f12.4,明确地被表示并且在细菌房间和早胚胎定位了;当基因被击倒时,卵子发生被破坏,窝尺寸被减少。除了繁殖显型,我们发现 c30f12.4 的损失改变胖新陈代谢,导致减少的胖存储和更小的类脂化合物微滴。同时, c30f12.4 异种蠕虫显示弄短的 lifespan。我们的结果在在 C 调整复制,胖动态平衡,和老化为 c30f12.4 加亮一个重要角色。elegans,它帮助我们更好理解在这些过程之间的关系。 | Lu Wang Fei Xu Guishuan Wang Xiaorong Wang Ajuan Liang Hefeng Huang Fei Sun | 2016 | Protein & Cell2016，7，10： | 0 |
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