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| 1 | Next generation patient-derived prostate cancer xenograft models显示文摘对为前列腺癌症的更有效的治疗学的途径有批评需要。然而,在这个区域的研究被缺乏严重妨碍了临床上相关,在疾病的 vivo 模型试验性。这评论特别地基于 patients’ 的 subrenal 囊 grafting 集中于前列腺癌症异种皮移植模型的发展;进 nonobese 糖尿病 / 严重的肿瘤组织联合了 immunodeficient (NOD/SCID ) 老鼠。这种技术允许可移植的、导出病人的癌症织物异种皮移植线的成功的开发从不仅好攻击变形,而且从局部性的前列腺癌症纸巾。异种皮移植被发现了保留原来的恶意的关键生物性质,包括组织病理学说、分子的特征,肿瘤异质,对雄激素脱离的反应和变形能力。因此,他们是高度临床上相关并且在细胞、分子的层次,为个性化的癌症治疗屏蔽的药和现出症状之前的潜的药为前列腺癌症前进的研究提供珍贵工具测试的功效;特别当模型的一块面板习惯于盖子时许多疾病。这些异种皮移植模型能因此被看作前列腺癌症的下一代的模型。 | Dong Lin Hui Xue Yuwei Wang Rebecca Wu Akira Watahiki Xin Dong Hongwei Cheng Alexander W Wyatt Colin C Collins Peter W Gout Yuzhuo Wang | 2014 | Asian Journal of Andrology2014，16，3： | 4 |
| 2 | 臂间血压差与脑卒中的关系显示文摘为了检测同时测量的双臂血压差值是否可识别踝臂血压指数〈0.90的受试者,及是否能预测未来心血管事件,Hirofumi等收集来自10个队列的日本受试者13 317人的数据(基于一般人群的队列,既往有心血管事件病史的队列及有心血管病危险因素的队列)进行荟萃分析。 | 刘青 叶鹏 Hirofumi T Toshiaki O Toshiharu N Chisa M Kazuomi K Satoshi H Yoshikuni K Toyoshi I Yasutaka M Katsuhiko K Yasuharu T Motoyuki N Takayoshi O Hirotaka W Masanori M Mitsuru O Norihisa I Michinari N Tetsuo S Charalambos V Akira Y | 2018 | 中华高血压杂志2018，26，6： | 3 |
| 3 | Cardio - ankle vascular index is superior to brachial - ankle pulse wave velocity as an in- dex of arterial tiffness 显示文摘 | Akira T Hiroshi O Takatoshi W | 2013 | Hypertens Res2013，31，7： | 1 |
| 4 | Spectral - domain optical coherence tomography images of inner/outer segment junctions and macular hole surgery outcomes显示文摘 | Maiko I Yoichiro W Akira A Shimpei S Satoshi K Kazuaki K | 2009 | Graefes Arch Clin Exp Ophthalmol2009，247，10： | 1 |
| 5 | Serum (1-3) β-D-Glucan noninvasive adjunct marker for the diagnosis of Pneumocystis pneumonia in patients with AIDS显示文摘 | Tamayo W Akira Y Junko T etal | 2009 | Clin Infect Dis2009，49，9： | 1 |
| 6 | R&D Spillovers, Patents and theIncentives to Innovate in Japan and the United States 显示文摘 | Cohen W M Akira Goto | 2002 | Research Policy2002，，31： | 1 |
| 7 | Mapping from ASRER stereo image data: DEM validation and accuracy assessment显示文摘 | Akira H Roy W Harold L | 2003 | Journal of Photogrammetry & Remote Sensing2003，57，： | 1 |
| 8 | Key Technologies for High Accuracy Large Mesh Antenna Reflectors显示文摘 | Akira M Sateshi H Mitsunobu W | 2003 | Acta Astronautica2003，53，： | 1 |
| 9 | Phenylethanoid and lignan glycosides from Verbascum thapsus显示文摘 | Tsutomu W Toshio M Akira U | 1992 | Phytochemistry1992，31，3： | 1 |
| 10 | Coefficients of friction of TiN coatings with preferred grain orientations under dry condition 显示文摘 | AKIRA A YASUO T HIRYUKI W | 2008 | Wear2008，265，78： | 1 |
| 11 | Semiquantive GC/MS analysis of thermochemolysis products of soil humic acids with various degrees of humification 显示文摘 | KOSUKE L SHUICHI Y AKIRA W | 2004 | Organic Geochemistry2004，35，： | 1 |
| 12 | Induction of receptor for advanced glycation end products by EBV latent membrane protein 1 and its correlation with angiogenesis and cervical lymph node metastasis in nasopharyngeal carcinoma显示文摘 | AKIRA T NAOHIRO W SATORU K | 2008 | Clin Cancer Res2008，14，17： | 1 |
| 13 | An opposing view on WWOX protein function as a tumor suppressor 显示文摘 | Akira W Yoshitaka H Hirokazu T | 2003 | Cancer Research2003，63，15： | 1 |
| 14 | Characteristics of water-absorbentpolymer emulsions显示文摘 | Naotaka W Yoshio Akira T | 1993 | Polymerlnternational1993，30，4： | 1 |
| 15 | A new trajectory analysis method for migratory planthoppers, Sogatella furcifera (Horvath) ( Homoptera: Delpbacidae) and Nilaparvata lugens (Stal) , using an advanced weather forecast model显示文摘 | Akira O Jimy D Tomonari W | 2005 | Agricultural and Forest Entomology2005，7，： | 1 |
| 16 | Characteristics of water-absorbent polymer emulsions显示文摘 | NAOTAKA W YOSHIO H AKIRA T | 1993 | Polymer International1993，30，4： | 1 |
| 17 | A sensitive enzyme immunoassay for human basic fibroblast growth factor显示文摘 | Hiroyuki W Akira H Masaharu S | 1991 | Biochemical and Biophysical Research Communications1991，175，1： | 1 |
| 18 | Photosynthetic bioelectrochemical cell utilizing cyanobacteria and watergenerating oxidasc显示文摘 | SCIVA T AKIRA W KENJI K | 2001 | Enzyme and Microbial Technology2001，29，2： | 1 |
| 19 | Key technologies for high accuracy large mesh antenna reflectors 显示文摘 | AKIRA M SATESHI H MITSUNOBU W | 2003 | Acta Astronautiea2003，53，11： | 1 |
| 20 | Contributions of humic subslances to the dissolved organic carbon pool in wetlands from different climates显示文摘 | Akira W Kunio M Hiromu S | 2012 | Chemosphere2012，，88： | 1 |
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