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5篇 您的检索式：作者名="Akoma"

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		题名	作者	年代	出处	被引量
	1	Antidiarrhoeal activity of leaf methanolic extract of Rauwolfia serpentina显示文摘Objective:To evaluate the antidiarrhoeal property of methanol extract of the leaves of Rauwolfia serpentina(R. serpentina) in experimental diarrhoea induced by castor oil in mice.Methods:Doses of 100, 200 and 400 mg/kgR. serpentinaleaf methanol extracts were administered to castor oil induced diarrhoea mice to determine its antidiarrhoeal activity.Results:All doses of the extract and the reference drug atropine sulphate(3 mg/kg, i.p.) produced a dose-dependent reduction in intestinal weight and fluid volume. The extracts also significantly reduced the intestinal transit in charcoal meal test when compared to diphenoxylate Hcl(5 mg/kg, p.o.).Conclusions:The results show that the extract of R. serpentin a leaves has a significant antidiarrhoeal activity and supports its traditional uses in herbal medicine.	Ezeigbo II Ezeja MI Madubuike KG Ifenkwe DC Ukweni IA Udeh NE Akomas SC	2012	Asian Pacific Journal of Tropical Biomedicine2012，2，6：	4
	2	Antidiarrheal activity of Pterocarpus erinaceus methanol leaf extract in experimentally-induced diarrhea显示文摘Objective:To investigate the antidiarrheal activity of the methanol leaf extract of Pterocarpus erinaceus in vivo.Methods:The methanol leaf extract of Ptemcarpus erinaceus was evaluated using different doses(100,200 and 400 mg/kg body weight) orally for antidiarrheal activity using castor oil-induced diarrhea,charcoal meal transit lime and castor oil-induced enteropooling in different groups of albino Wistar mice.The activity of the extract at different doses were compared to diphenoxylate(3 mg/kg) and atropine sulphate(3 mg/kg) which were used as standard reference drugs and also to the distilled water administered negative control group of mice.Results:The extract at the doses used caused a significant(P< 0.01) reduction in the wet faeces passed by the mice in the castor oil-induced diarrhea,decreased the distance travelled by the charcoal meal by up to 54.8%and also caused a dose dependent and significant(P< 0.001) reduction in the intraluminal fluid accumulation in the castor oil-induced enteropooling. Conclusions:Our results indicate that Pterocarpits erinaceus extract produced significant antidiarrheal activity and the action may attribute to inhibition of gastrointestinal movement and fluid secretion.	Ezeja Maxwell I Ezeigbo Ihechiluru I Madubuike Kelechi G Udeh Nkiru E Ukweni Iheanacho A Akomas Stella C Ifenkwe Daniel C	2012	Asian Pacific Journal of Tropical Medicine2012，5，2：	3
	3	Circulation endothelial cell adhesion molecules as diagnostic markers for the early identification of pregnant women at risk for development of preeclampsia 显示文摘	Krauss T Kuhn W akoma C	1997	Am J Obstet Gynecol1997，177，2：	1
	4	The “Trick” of Narratives:History,Memory,and Performance in Toni Morrison' s Paradise显示文摘	Akoma Chiji		0，，：	1
	5	Heat sensitization of Bacillus subtilis spores by selected spices显示文摘	Blank G G Akomas	1988	J Food Safety1988，，9：	1

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