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| 1 | Ranibizumab in diabetic macular edema显示文摘By 2050 the prevalence of diabetes will more than triple globally,dramatically increasing the societal and financial burden of this disease worldwide.As a consequence of this growth,it is anticipated that there will be a concurrent rise in the numbers of patients with diabetic macular edema(DME),already among the most common causes of severe vision loss worldwide.Recent available therapies for DME target the secreted cytokine,vascular endothelial growth factor(VEGF).This review focuses on the treatment of DME using the first humanized monoclonal antibody targeting VEGF that has been Food and Drug Administrationapproved for the use in the eye,ranibizumab(Lucentis). | Claudia Krispel Murilo Rodrigues Xiaoban Xin Akrit Sodhi | 2013 | World Journal of Diabetes2013，4，6： | 2 |
| 2 | Regression of Choroidal Neovascularization in Response to Systemic Chemotherapy for Cancer显示文摘 | Annie W. Hsu Akrit Sodhi Charles Eberhart Silvia Montaner Morton F. Goldberg | 2013 | Canadian Journal of Ophthalmology/Journal canadien d’ophtalmologie2013，，： | 1 |
| 3 | Mammalian target of rapamycin, a molecular target in squamous cell carcinomas of the head and neck 显示文摘 | Panomwat A Vyomesh P Akrit S | 2005 | Cancer Res2005，65，21： | 1 |
| 4 | Recent Trends in the Management of Rhegmatogenous Retinal Detachment显示文摘 | Akrit Sodhi Loh-Shan Leung Diana V. Do Emily W. Gower Oliver D. Schein James T. Handa | 2008 | Survey of Ophthalmology2008，，1： | 1 |
| 5 | Optical coherence tomography enhanced depth imaging of chorioretinal folds in patients with orbital tumors显示文摘AIM:To characterize spectral-domain optical coherence tomography(SD-OCT)features of chorioretinal folds in orbital mass imaged using enhanced depth imaging(EDI).METHODS:Prospective observational case-control study was conducted in 20 eyes of 20 patients,the uninvolved eye served as a control.All the patients underwent clinical fundus photography,computed tomography,EDI SDOCT imaging before and after surgery.Two patients with cavernous hemangiomas underwent intratumoral injection of bleomycin A5;the remaining patients underwent tumor excision.Patients were followed 1 to 14mo following surgery(average follow up,5.8mo).RESULTS:Visual acuity prior to surgery ranged from 20/20 to 20/200.Following surgery,5 patients’visual acuity remained unchanged while the remaining 15 patients had a mean letter improvement of 10(range 4 to 26 letters).Photoreceptor inner/outer segment defects were found in 10 of 15 patients prior to surgery.Following surgical excision,photoreceptor inner/outer segment defects fully resolved in 8 of these 10 patients.CONCLUSION:Persistence of photoreceptor inner/outer segment defects caused by compression of the globe by an orbital mass can be associated with reduced visual prognosis.Our findings suggest that photoreceptor inner/outer segment defects on EDI SD-OCT could be an indicator for immediate surgical excision of an orbital mass causing choroidal compression. | Zhi-Yu Peng Lu Gan Kang Xue Akrit Sodhi Xiao-Feng Ye Hui Ren Jiang Qian | 2023 | International Journal of Ophthalmology(English edition)2023，16，2： | 0 |
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