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| 1 | Nat Genet:单基因突变导致过敏性皮炎的发生显示文摘最近,研究者们鉴定出了一类导致神经性皮炎发生的关键基因突变:CARDll。来自美国NIH过敏与传染病研究所的研究者们通过对四个没有血缘关系的患病家庭进行分析,发现了这一导致疾病产生的基因、 | Chi A Ma, Yuan Zhang, Michael A Weinreich, Jonathan J Lyons, Celeste G Nelson, Thomas DiMaggio, Kelly D Stone, Joshua D Milner Jeffrey R Stinson, Elisa Ruffo, Batsukh Dorjbal, Swadhinya Arjunaraja, Kelsey Voss, Andrew L Snow Jordan K Abbott, Pia J Hauk, Paul R Reynolds, Erwin W Gelfand Elisa Ruffo Salomé Glauzy, Natsuko Yamakawa, Eric Meffre Jennifer Stoddard, Julie Niemela, Sergio D Rosenzweig Yu Zhang, Helen F Matthews Joshua J McElwee Nina Jones Alejandro Palma, Matías Oleastro, Emma Prieto, Andrea R Bernasconi, Geronimo Dubra, Silvia Danielian, Jonathan Zaiat, Marcelo A Marti Brian Kim Megan A Cooper Neil Romberg | 2017 | 现代生物医学进展2017，17，27： | 3 |
| 2 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 3 | Carbon nanotubes as reinforcement of styrene-butadiene rubber 显示文摘 | Alejandro D F Silvia G Gerardo H R | 2007 | Applied Surface Science2007，254，1： | 1 |
| 4 | Carboxylate-based molybdenum alkylidene catalysts:Synthesis,characterization,and use as initiators for 1,6-heptadiyne cyclopolymerizations显示文摘 | Richard R Schrock Zachary J Tonzetich Alejandro G Lichtscheidl | 2008 | Organometallics2008，，： | 1 |
| 5 | Specific CAPN10 gene haplotypes influence the clinical profile of polycystic ovary patients显示文摘 | Alejandro G Eduardo A Alfredo R | 2003 | J Clin Endcorinol Metab2003，88，11： | 1 |
| 6 | Bioremediation of crude oil polluted seawater by a hydrocarbon-degrading bacterial strain immobilized on chitin and chitosan flakes 显示文摘 | ALEJANDRO R G MAR A C AERRE R O | 2006 | Int Biodeter Biodegr2006，57，4： | 1 |
| 7 | Heart valve calcification and calcium phosphorus product in hemodialysis patients:Analysis of optimum values for its prevention显示文摘 | Margarita R Sagrario G Alejandro J | 2003 | Kidney International2003，16，385： | 1 |
| 8 | Life-history traits of the giant squid Architeuthis dttx revealed from stable isotope signatures recorded in beaks 显示文摘 | ANGEL GUERRA ALEJANDRO B R ANGEL F G | 2010 | ICES Journal of Marine Science2010，16，7： | 1 |
| 9 | Achievement of insulin independence via pancreatic islet transplantation using a remote isolation center: a first-year review显示文摘 | N.R Barshes T Lee S Goodpasture F.C Brunicardi R Alejandro C Ricordi G Soltes M Barth D Hamilton J.A Goss | 2004 | Transplantation Proceedings2004，，4： | 1 |
| 10 | Carbon nanotubes as reinforcement of styrene-butadiene rubber显示文摘 | Alejandro D F Silvia G Gerardo H R | 2007 | Applied Sur- face Science2007，254，1： | 1 |
| 11 | Bioremediation of crude oil polluted seawater by a hydrocarbon-degrading bacterial strain immobilized on chitin and chitosan flakes显示文摘 | Alejandro R G Mar A C Ferre-R O | 2006 | International Biodete-rioration & Biodegradation2006，57，4： | 1 |
| 12 | Reversion of deleterious effects of salt stress by activation of ROS detoxifying enzymes via foliar application of 24-epibrassinolide in rice seedlings显示文摘 | Yanelis R G Lisbel M G José D A Miriam N Alejandro J P | 2015 | Theoretical and Experimental Plant Physiology2015，27，1： | 1 |
| 13 | Bioremediation of crude oil polluted seawater by a hydrocarbon-degrading bacterial strain immobilized on chitin and chitosan flakes显示文摘 | ALEJANDRO R G MARIA A C MARCELA FERRERO | 2006 | International Biodeterioration & Biodegradation2006，57，4： | 1 |
| 14 | Marine pharmacology in 2007--8: Marine compotmds with antibacterial, anticoagulant, antifungal, anti-inflammatory, antimalarial, antipmtozoal, antituberculosis, and antiviral activities; affecting the immune and nervous system, and other miscellaneous mechanisms of action显示文摘 | ALEJANDRO M S M ABIMAEL D R ROBERTO G S B | 2011 | Comparative Biochemistry and Physiology: Part C2011，153，2： | 1 |
| 15 | Herpes SimplexVirus Keratitis : Epidemiological Observations 显示文摘 | Virgilio G Alejandro T Mario L R | 2013 | Survey of Ophthalmology2013，58，3： | 1 |
| 16 | Biore- mediation of Crude Oil Polluted Seawater by a Hydro- carbon-Degrading Bacterial Strain Immobilized on Chitin and Chitosan Flakes显示文摘 | Alejandro R G Maria A C Ferrero M | 2006 | International Biodete- rioration & Biodegradation2006，57，4： | 1 |
| 17 | Transformation of undomesticated strains of Bacillus subtilis by protoplast eleetroporation显示文摘 | Diego R A Alejandro P G Jan W V | 2006 | J Mierobiol Methods2006，66，： | 1 |
| 18 | Multiple limit cycles in a Cause type predator - prey model with Holling type HI functional response and Allee effect on prey 显示文摘 | Eduardo G Alejandro R | 2011 | Bull Math Biol2011，71，： | 1 |
| 19 | Presence of Echinococcus oligarthrus (Diesing, 1863) Luhe, 1910 in Lynx rufus texensis Alien, 1895 from San Fernando, Tamaulipas State, in north-east Mexico显示文摘 | NARCISO S L FERNANDO J G ALEJANDRO C R | 1996 | Int J Parasltol1996，26，7： | 1 |
| 20 | Inhibition effects observed between dibenzothiophene and carbazole during the hydrotreating process 显示文摘 | LAREDO G C ALEJANDRO M ANTONIO D L R J | 2004 | Applied Catalysis A: General2004，265，1： | 1 |
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