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| 1 | Spreading depression and focal venous cerebral ischemia enhance cortical neurogenesis显示文摘Endogenous neurogenesis can arise from a variety of physiological stimuli including exercise, learning, or 'enriched environment' as well as pathological conditions such as ischemia, epilepsy or cortical spreading depression. Whether all these conditions use a common trigger to set off endogenous neurogenesis is yet unclear. We hypothesized that cortical spreading depression(CSD) induces neurogenesis in the cerebral cortex and dentate gyrus after cerebral venous ischemia. Forty-two Wistar rats alternatively underwent sham operation(Sham), induction of ten CSDs or venous ischemia provoked via occlusion of two adjacent superficial cortical vein followed by ten induced CSDs(CSD + 2-VO). As an additional control, 15 na?ve rats received no intervention except 5-bromo-2′-deoxyuridine(Brd U) treatment for 7 days. Sagittal brain slices(40 μm thick) were co-stained for Brd U and doublecortin(DCX; new immature neuronal cells) on day 9 or Neu N(new mature neuronal cells) on day 28. On day 9 after sham operation, cell proliferation and neurogenesis occurred in the cortex in rats. The sole induction of CSD had no effect. But on days 9 and 28, more proliferating cells and newly formed neurons in the ipsilateral cortex were observed in rats subjected to CSD + 2VO than in rats subjected to sham operation. On days 9 and 28, cell proliferation and neurogenesis in the ipsilateral dentate gyrus was increased in sham-operated rats than in na?ve rats. Our data supports the hypothesis that induced cortical neurogenesis after CSD + 2-VO is a direct effect of ischemia, rather than of CSD alone. | Ryo Tamaki Samuel Ige Orie Beat Alessandri Oliver Kempski Axel Heimann | 2017 | Neural Regeneration Research2017，12，8： | 3 |
| 2 | An economic capital model integrating credit and interest rate risk in the banking book显示文摘 | Piergiorgio Alessandri Mathias Drehmann | 2009 | Journal of Banking and Finance2009，，4： | 2 |
| 3 | On the cyclic behaviour of new pier-to-deck connections for short-medium span composite I-girder bridges显示文摘Short-medium span steeleconcrete composite I-girder bridges are becoming more and more popular, because of the reduced construction time and costs. The light weight renders them particularly suitable also is seismic areas, even though this advantage has not been yet adequately investigated. In fact, in case of seismic loading, significant tensile forces might be exhibited at the bottom flange of the steel girder, especially when monolithic connection between deck and pier is adopted, and the connection, conceived for sustaining prevailing hogging bending moments, could experience an excessive damage.With this aim, the cyclic behaviour of new pier-to-deck joints involving the use of concrete cross-beams(CCB) has been recently analysed within the European project(SEQBRI). This paper deals with the results of a wide experimental investigation of these new joints,performed with the aim of characterizing their hysteretic behaviour. Three different typologies were tested: one designed according to the German standard DIN-FB-104, generally utilized for gravity loads only, and other two types proposed for bridges located in low(VAR-1) and medium(VAR-2) seismicity. A series of displacement-imposed cyclic tests highlighted a good seismic behaviour of all the tested solutions. In particular, the DIN-FB-104 VAR C and VAR-2 displayed a similar global behaviour in terms of maximum force and displacement, but with a more pronounced crack development and buckling of steel girders of the first solution. The VAR-2 also avoids possible pull-out phenomena in the CCB thanks to the beneficial action of pre-stressing bars.A damage analysis of the proposed connections was finally performed in view of the application of the performance-based earthquake engineering methodology and the quantification the seismic performance of this bridge typology, which was among the aims of SEQBRI project. | Fabrizio Paolacci Renato Giannini Silvia Alessandri Daniele Corritore | 2018 | Journal of Traffic and Transportation Engineering(English Edition)2018，5，6： | 2 |
| 4 | Docosahexaenoic acid (DHA) and the developing central nervous system (CNS) – Implications for dietary recommendations显示文摘 | Philippe Guesnet Jean-Marc Alessandri | 2010 | Biochimie2010，，1： | 2 |
| 5 | Development of a European Muhimodel Ensemble System for Seasonal - to - interannual Prediction 显示文摘 | Palmer T N Alessandri A Andersen U | 2004 | American Meteorological Society2004，，6： | 1 |
| 6 | optimal control of freeways via speed signaling and ramp metering显示文摘 | ALESSANDRI A FEBBRARA A D FERRAM A | 1998 | Control Engineering Practice1998，6，6： | 1 |
| 7 | Orthodontic extraction: riskless extraction of impacted lower third molars close to the mandibular canal显示文摘 | ALESSANDRI BONETTI G BENDANDI M LAINO L | 2007 | J Oral Maxillofac Surg2007，65，12： | 1 |
| 8 | Osteo- porosis and risk of fracture in patients with diabetes: an update显示文摘 | Montagnani A Gonnelli S Alessandri M | 2011 | Aging Clin Exp Res2011，23，2： | 1 |
| 9 | Drugs improving insulin resistance for non-alcoholic fatty liver disease and/or non-alcoholic steatohepatitis显示文摘 | Angelico F Burattin M Alessandri C | 2007 | Cochrane Database Syst Rev2007，24，00： | 1 |
| 10 | Enhancing raman scattering without plasmons: Unprecedented sensitivity achieved by TiO2 shell-based resonators显示文摘 | Alessandri I | 2013 | Journal of the American Chemical Society2013，135，15： | 1 |
| 11 | A concept for the introduction of cerebral microdialysis in neurointensive care显示文摘 | Landolt H Langemann H Alessandri B | 1996 | Acta Neurochir Suppl1996，67，： | 1 |
| 12 | Infectious and uterus related complications during pregnancy and development of atopic and nonatopic asthma in children显示文摘 | CALVANI M ALESSANDRI C SOPO S M | 2004 | Allergy2004，59，1： | 1 |
| 13 | Huma vasculogenesis ex vi-vo: embryonal aorta as a tool for isolation of endothelial cel progenitors 显示文摘 | ALESSANDRI G GIRELI M TACCAGNI G | 2001 | Lab Invest2001，81，： | 1 |
| 14 | Improvement of blood gas levels after calcium heparin treatment in patients with chronic obstructive pulmonary disease显示文摘 | Cordova C Violi F Alessandri C | | 0，，03： | 1 |
| 15 | Arc-length procedures with BEM in physically nonlinear problems显示文摘 | MALLARDO ALESSANDRI C | 2004 | Engineering Analysis with Boundary Elements2004，28，6： | 1 |
| 16 | Insulin Resistance, the Metabolic Syndrome, and Nonalcoholic Fatty Liver Disease显示文摘 | F Angelico M Del Ben R Conti S Francioso K Feole S Fiorello M G. Cavallo B Zalunardo F Lirussi C Alessandri F Violi | 2005 | The Journal of Clinical Endocrinology & Metabolism2005，，3： | 1 |
| 17 | The neuroprotective effect of lactate is not due toimproved glutamate uptake after con- trolled cortical impact in rats 显示文摘 | Alessandri B Schwandt E Kamada Y | 2012 | J Neurotrauma2012，29，12： | 1 |
| 18 | Mesenchymal Stem/Stromal Cells: A New ’’Cells as Drugs’’ Paradigm. Efficacy and Critical Aspects in Cell Therapy显示文摘 | Laura de Girolamo Enrico Lucarelli Giulio Alessandri Maria Antonietta Avanzini Maria Ester Bernardo Ettore Biagi Anna Teresa Brini Giovanna D’Amico Franca Fagioli Ivana Ferrero Franco Locatelli Rita Maccario Mario Marazzi Ornella Parolini Augusto Pessina | 2013 | Current Pharmaceutical Design2013，，： | 1 |
| 19 | Human vasculogenesisex vivo:embryonal aorta as a tool for isolation of endothelial cell progenitors显示文摘 | Girelli M Taccagni G | 2001 | Lab Invest2001，81，： | 1 |
| 20 | Towards a Framework for Quantifying Systemic Stability 显示文摘 | ALESSANDRI P GAI P KAPADIA S | 2009 | International Journal of Central Banking2009，5，3： | 1 |
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