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52篇 您的检索式:作者名="Alex T C"
    题名 作者 年代 出处 被引量
1Chronic overexpression of PNPLA3^sup I148M^ in mouse liver causes hepatic steatosis显示文摘Li John Zhong Huang Yongcheng Karaman Ruchan Ivanova Pavlina T Brown H Alex Roddy Thomas Castro-Perez Jose Cohen Jonathan C Hobbs Helen H 2012EN2012,,11:3
2A Revised Weighted Sum Decision Model for Robot Selection显示文摘Goh C H Alex T Y C Cheng Chun-Hung 1996Computers and Industrial Engineering1996,30,2:1
3The future renewable electric energy delivery and management system: the energy internet 显示文摘Alex H Mariesa L C Gerald T H 2011Proceedings of the IEEE2011,99,1:1
4A genetic algorithm for solving a capacitated P - median problem 显示文摘ELON S C MARIA T A S ALEX A F 2003Numeric Algorithm2003,35,4:1
5成人2型糖尿病不同筛查及预防策略成本效益分析显示文摘目的 比较针对2型糖尿病预防及治疗的4种筛查策略及随后予以的干预措施:(a)筛查2型糖尿病患者使其能接受早期检查及治疗,(b)筛查2型糖尿病和糖耐量受损患者,对糖耐量受损的人群予以生活方式干预以延缓或预防糖尿病的发生,(c)同(b)但予以药物干预措施,(d)不筛查。 设计 成本效益决策分析建立在对概率的发展和评估基础上,是从筛查到死亡的综合性经济决策分析模型。 研究对象 一组假设人群,筛查时年龄45岁,高于平均糖尿病风险水平。 数据来源 电子书目数据库收录的已发表的临床试验和流行病学研究;补充数据分别来自英国和威尔士健康统计署、风险筛查(STAR)研究和ADDITION研究的Leicester部分。 方法 建立一种决策树/Markov混合模型,以模拟每一种筛查策略的长期效用,包括临床和成本效益终点。该模型假设水平跨度为50年时间,其成本效益折损率为3.5%。采用敏感度分析以验证模型假设及确定哪种模型数据输入对结果的影响最大。 结果 与不筛查策略比较,筛查2型糖尿病、筛查糖尿病和糖耐量受损并予以生活方式干预、筛查糖尿病和糖耐量受损并予以药物干预治疗3种策略,每获得一个质量调整生命年(QALY)估计所需成本分别为(每年成本效益贴现率为3.5%)14150英镑(17560欧元;27860美元)、6242英镑和7023英镑。在支付意愿阈值为20000英镑时,各主动筛查策略通过干预产生的成本效益概率分别为49%,93%和85%。 结论 对年龄45岁、高于平均风险水平的人群进行2型糖尿病和糖耐量受损的筛查,并对糖耐量受损人群予以适当的干预似乎具有很好的成本效益。单独筛查糖尿病而不对糖耐量受损人群予以干预的策略具有的成本效益仍不确定,需要进一步研究确定早期检测糖尿病的作用。Clare L Gillies Paul C Lambert Keith R Abrams Alex J Sutton Nicola J Cooper Ron T Hsu Melanie J Davies Kamlesh Khunti 张晓梅(译) 纪立农(校) 2008英国医学杂志中文版2008,11,5:1
6Sentinel lymph node radiolocalization in head and neck squamous carcinoma显示文摘ALEX J C SASAKI C T KRAG D N 2000Larygoscope2000,110,:1
7Physical and chemical fractionation of dissolved organic matter and trihalomethane precursors: A review 显示文摘Alex T C Suduan G Randy A D 2005Joumal of Water Supply: Research and Technology-AQUA2005,54,8:1
8Effects of yttrium on the sintering and microstructure of alumina-silicon carbide 'nanocomposites' 显示文摘ALEX M C IAN P S RICHARD I T STEVE G R 2005J Am Ceram Soc2005,88,9:1
9An overview on the production of pigment grade titania from titania-rich slag 显示文摘Sahu K K Alex T C Mishra D 2006Waste management&research2006,24,1:1
10Characterization of polyploid wheat genomic diversity using a high-density 90 000 single nucleotide polymorphism array 显示文摘Wang SC Debbie W Kerrie F Alexandra A Shiaoman C Bevan EH Marco M Silvio S Sara GM Luigi C Anna MM Alex W Stuart S Gary B Ralf W Joerg P International Wheat Genome Sequencing Consortium Morten L Diane M Rudi A Rudy D Gina BG Abraham K Alina RA Catherine F Jerome S Michele M Curtis P Luo MC Jan DMM Jorge D Martin G Roberto T Cindy L Ivan M Colin C Keith JE Matthew H Eduard A 2014Plant Biotechnol J2014,12,:1
11A population-based study of the drug interaction between proton pump inhibitors and clopidogrel显示文摘Juurlink David N Gomes Tara Ko Dennis T Szmitko Paul E Austin Peter C Tu Jack V Henry David A Kopp Alex Mamdani Muhammad M 2009Canadian Medical Association. Journal2009,,7:1
12Lobar holoprosencephaly:prenatal MR diagnosis withpostnatal MR correlation显示文摘Alex M Wong C Larissa T Bilaniuk K.-K.Ng 0,,04:1
13Gefitinib plus best sup- portive care in previously treated patients with refractory advanced non-small-cell lung cancer:results from a ran- domised,placebo controlled,muhicentre study (Iressa Survival Evaluation in Lung Cancer)显示文摘Nick T Alex C Purvish P 2005Lancet Oncol2005,366,9496:1
14Prediction of equivalent steady-state chloride diffhsion coefficients显示文摘Pratanu C~ Alex H Paul J T 2011ACI Materials Journal2011,108,1:1
15Anticoagula- tion during haemodialysis using a citrate-enriched di- alysate: a feasibility study显示文摘Yuk-Lun C Alex WY Kwong-Yuen T 2011Nephrol Dial Trans- plant2011,26,2:1
16Advanced glycation end products induce angiogenesis in vivo显示文摘Tamami O Shinya T Alex C 2002Microvasc2002,63,2:1
17Memory and the everyday land- scape of violence in post -genocide Cambodia显示文摘James A T Gabriela B A Alex R C 2012Social and Cultur- al Geography2012,13,8:1
18Anomalous reduction in surface area during mechanical activation of boehmite synthesized by thermal decomposition of gibbsite 显示文摘Alex T C Rakesh K Roy S K 2011Powder Technology2011,208,1:1
19Benchmark radar targets for the validation of computational electromagnetics problems显示文摘Woo Alex C Wang Helen T G Schuh Michael J Sandeers Michael L 1993IEEE Antennas and Propagation Magazine1993,35,1:1
20SuperspreadingDriven by Marangoni Flow显示文摘ALEX D N DARSH T W ANOOP C 2002Advances in Colloid and InterfaceScience2002,96,:1
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