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16篇 您的检索式:作者名="Alexis U"
    题名 作者 年代 出处 被引量
1Vitamin D status and parathyroid hormone in obese children before and after weight loss显示文摘Reinehr T de Sousa G Alexy U 2007Eur J Endoerinol2007,157,2:1
2Vitamin D status and parathyroid hormone in obese children before and after weight loss显示文摘Reinehr T de Sousa G Alexy U 2007Eur J Endocrinol2007,157,2:1
3Vitamin D status and parathyroid hormone in obese children before and after weight loss显示文摘Reinehr T de Sousa G Alexy U 2007Eur J Endocrinol2007,157,2:1
4Coronary artery bypass grafting in octogenarians-outcome with and without extracorporeal circulation显示文摘Tugtekin S Kappert U Alexiou K 2007Thorac Cardiovasc Surg2007,55,7:1
5PUFA and LC-PUFA intake during the first year of life: can dietary practice achieve a guideline diet?显示文摘Schwartzl J Dubel K Alexy U 2010Euro J Clin Nutr2010,641,:1
6Longterm protein intake and dietary potential renal acid load are associated with bone modeling and remodeling at the proximal radius in healthy children显示文摘Alexy U Remer T Manz F Neu CM Schoenau E 0,,05:1
7Vitamin D status and parathyroid hormone in obese children before and after weight loss显示文摘Reinehr T de Sousa G Alexy U Kersting M Andler W 0,,:1
8Vitamin D status and parathyroid hormone in obese children before and after weight loss显示文摘Reinehr T de Sousa G Alexy U 0,,02:1
9Combination of tumor neerosis factor-related apoptosis-inducing Ligand(TRAIL)and actinomycin D induces apoptosis even in TRAIL resistant human pancreatic cancer cells显示文摘Matsuzaki H Bruno MS Alexis U 2001Clin Cancer Res2001,7,3:1
10Using the concept of Food Based Dietary Guidelines to Develop an Optimized Mixed Diet(OMD)for German children and adolescents显示文摘Kersting M Alexy U Clausen K 2005J Pediatr Gastroenterol Nutr2005,40,3:1
11Dietary intake and food sources of minerals in 1 to 18 year old German children and adolescents 显示文摘Kersting M Alexy U Sichert-Hellert W 2001Nutrition Research2001,21,4:1
12Vitamin D status and parathyroid hormone in obese children before and after weight loss显示文摘Reinehr T de Sousa G Alexy U 2007Eur J Endocrinol2007,157,2:1
13Cluster analysis of individuals with similar trends of fat intake during childhood and adolescence: a new approach to analyzing dietary data 显示文摘ALEXY U VERENA S P WOLFGANG S H 2005Nutrition Research2005,25,3:1
14A portable surface plasmon resonance (SPR) sensor systerm with temperature regulation显示文摘ALEXI N N SCOLL D S DWIGHT U B 2003Sensors and Actuators B2003,96,2:1
15Vitamin D status and parathyroid hormone in obese children before and after weight loss 显示文摘Reinehr T de Sousa G Alexy U 2007Eur J Endocrinol2007,157,2:1
16Factors associated with success of telaprevir-and boceprevir-based triple therapy for hepatitis C virus infection显示文摘AIM To evaluate new therapies for hepatitis C virus(HCV), data about real-world outcomes are needed.METHODS Outcomes of 223 patients with genotype 1 HCV who started telaprevir-or boceprevir-based triple therapy(May 2011-March 2012) at the Mount Sinai Medical Center were analyzed. Human immunodeficiency viruspositive patients and patients who received a liver transplant were excluded. Factors associated with sustained virological response(SVR24) and relapse were analyzed by univariable and multivariable logistic regression as well as classification and regression trees. Fast virological response(FVR) was defined as undetectable HCV RNA at week-4(telaprevir) or week-8(boceprevir). RESULTS The median age was 57 years, 18% were black, 44% had advanced fibrosis/cirrhosis(FIB-4 ≥ 3.25). Only 42%(94/223) of patients achieved SVR24 on an intention-totreat basis. In a model that included platelets, SVR24 was associated with white race [odds ratio(OR) = 5.92, 95% confidence interval(CI): 2.34-14.96], HCV sub-genotype 1b(OR = 2.81, 95%CI: 1.45-5.44), platelet count(OR = 1.10, per x 104 cells/μL, 95%CI: 1.05-1.16), and IL28 B CC genotype(OR = 3.54, 95%CI: 1.19-10.53). Platelet counts > 135 x 103/μL were the strongest predictor of SVR by classification and regression tree. Relapse occurred in 25%(27/104) of patients with an end-oftreatment response and was associated with non-FVR(OR = 4.77, 95%CI: 1.68-13.56), HCV sub-genotype 1a(OR = 5.20; 95%CI: 1.40-18.97), and FIB-4 ≥ 3.25(OR = 2.77; 95%CI: 1.07-7.22). CONCLUSION The SVR rate was 42% with telaprevir-or boceprevirbased triple therapy in real-world practice. Low platelets and advanced fibrosis were associated with treatment failure and relapse.Kian Bichoupan Neeta Tandon Valerie Martel-Laferriere Neal M Patel David Sachs Michel Ng Emily A Schonfeld Alexis Pappas James Crismale Alicia Stivala Viktoriya Khaitova Donald Gardenier Michael Linderman William Olson Ponni V Perumalswami Thomas D Schiano Joseph A Odin Lawrence U Liu Douglas T Dieterich Andrea D Branch 2017World Journal of Hepatology2017,9,11:0
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