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| 1 | Antibacterial efficacy of the seed extracts of Melia azedarach against some hospital isolated human pathogenic bacterial strains显示文摘Objective:To investigate the antibacterial potential of the polar and non-polar extracts of the seeds of Melia azedarach(M.azedarach) L.(Meliaceae) against eighteen hospital isolated human pathogenic bacterial strains.Methods:Petrol,benzene,ethyl acetate,methanol,and aqueous extracts at five different concentrations(1,2,5,10 and 15 mg/mL) were evaluated.Disk diffusion method was followed to evaluate the antibacterial efficacy.Results:All extracts of the seeds demonstrated significant antibacterial activity against tested pathogens.Among all extracts,ethyl acetate extract revealed the highest inhibition comparatively.The present study also favored the traditional uses reported earlier.Conclusions:Results of this study strongly confirm that the seed extracts of M.azedarach could be effective antibiotics,both in controlling gram-positive and gram-negative human pathogenic infections. | Abdul Viqar Khan Qamar Uddin Ahmed M Ramzan Mir Indu Shukla Athar Ali Khan | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，6： | 11 |
| 2 | Detection and sequencing of plasmid encoded tetracycline resistance determinants(tetA and tetB) from food-borne Bacillus cereus isolates显示文摘Objective:To investigate the detection and sequencing of plasmid encoded tetracycline resistance genes(tet A and tet B) from food-borne and standard strains of Bacillus cereus(B. cereus).Methods:PCR was carried out to detect the tetracycline resistance genes(tet A and tet B) in food-borne B.cereus strains and the amplified products were sequenced.Results:The phenotypic resistance against tetracycline was observed in 39 of the 118 food-borne isolates and two reference strains(MTCC 430 and MTCC 1307) of B.cereus.Among the phenotypically resistant isolates,tet A was detected in 36 food-borne isolates and two reference strains(MTCC 430 and MTCC 1307).whereas,tel B was detected in 12 food-bome isolates and MTCC 1307 strain. Conclusions:A close association was therefore found between phenotypic resistance against tetracycline and presence of tetracycline resistance genes.The tet A and tet B gene fragments were amplified,purified and sequenced.The gene sequences of the isolates studied herein were found similar to tetA and tetB gene sequences of other bacteria available in NCBI.The occurrence of tetA and tetB genes in B.cereus indicate the horizontal transfer of antibiotic resistance determinants from other bacteria into B.cereus.The transfer of these resistant determinants to other potentially pathogenic bacteria may be a matter of great concern. | Mudasir Ali Rather Rabinder Singh Aulakh Jatinder Paul Singh Gill Abdul Qayoom Mir Mir Nadeem Hassan | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，9： | 6 |
| 3 | Transcranial magnetic stimulation in animal models of neurodegeneration显示文摘Brain stimulation techniques offer powerful means of modulating the physiology of specific neural structures. In recent years, non-invasive brain stimulation techniques, such as transcranial magnetic stimulation(TMS) and transcranial direct current stimulation, have emerged as therapeutic tools for neurology and neuroscience. However, the possible repercussions of these techniques remain unclear, and there are few reports on the incisive recovery mechanisms through brain stimulation. Although several studies have recommended the use of non-invasive brain stimulation in clinical neuroscience, with a special emphasis on TMS, the suggested mechanisms of action have not been confirmed directly at the neural level. Insights into the neural mechanisms of non-invasive brain stimulation would unveil the strategies necessary to enhance the safety and efficacy of this progressive approach. Therefore, animal studies investigating the mechanisms of TMSinduced recovery at the neural level are crucial for the elaboration of non-invasive brain stimulation. Translational research done using animal models has several advantages and is able to investigate knowledge gaps by directly targeting neuronal levels. In this review, we have discussed the role of TMS in different animal models, the impact of animal studies on various disease states, and the findings regarding brain function of animal models after TMS in pharmacology research. | Mohammad Uzair Turki Abualait Muhammad Arshad Woo-Kyoung Yoo Ali Mir Reem Fahd Bunyan Shahid Bashir | 2022 | Neural Regeneration Research2022，17，2： | 4 |
| 4 | Multigene genetic programming for sediment transport modeling in sewers for conditions of non-deposition with a bed deposit显示文摘It is known that construction of large sewers based on consideration of flow with non-deposition without a bed deposit is not economical. Sewer design based on consideration of flow with nondeposition with a bed deposit reduces channel bed slope and construction cost in which the presence of a small depth of sediment deposition on the bed increases the sediment transport capacity of the flow.This paper suggests a new Pareto-optimal model developed by the multigene genetic programming(MGGP) technique to estimate particle Froude number(Frp) in large sewers with conditions of sediment deposition on the bed. To this end, four data sets including wide ranges of sediment size and concentration, deposit thickness, and pipe size are used. On the basis of different statistical performance indices, the efficiency of the proposed Pareto-optimal MGGP model is compared to those of the best MGGP model developed in the current study as well as the conventional regression models available in the literature. The results indicate the higher efficiency of the MGGP-based models for Frp estimation in the case of no additional deposition onto a bed with a sediment deposit. Inasmuch as the Pareto-optimal MGGP model utilizes a lower number of input parameters to yield comparatively higher performance than the conventional regression models, it can be used as a parsimonious model for self-cleansing design of large sewers in practice. | Mir Jafar Sadegh Safari Ali Danandeh Mehr | 2018 | International Journal of Sediment Research2018，33，3： | 3 |
| 5 | Effect of Salvia officinalis Hydroalcoholic Extract on Vincristine-induced Neuropathy in Mice显示文摘AIM:Vincristine is one of the most commonly used chemotherapeutic drugs to treat a variety of malignant diseases,including leukemia and lymphoma.Studies have shown that vincristine cause painful effects,whereas Salvia officinalis(SO) showed analgesic and anti-inflammatory effects.The aim of this study is to investigate the effects of the SO hydro-alcoholic extract on vincristine-induced peripheral neuropathy in mice in comparison with morphine.METHODS:Experiments were performed on 60 NMRI male mice weighing 25-30 g divided into six groups.The individual groups received normal saline,SO hydro-alcoholic extract,vincristine,SO hydro-alcoholic extract and vincristine(12 days before formalin test),morphine,and vincristine and morphine,respectively.The injected hind paw biting and licking was measured in a 5-minute interval for one hour.RESULTS:The results showed that formalin induce significant(P < 0.05) pain responses(the first phase:0-5 min and the second phase:15-40 min after injection).Administration of SO extract before formalin test showed significant(P < 0.05) decrease of pain response in the second phase.Administration of vincristine caused significant(P < 0.05) increase in the second phase of pain response.Injections of SO extract and vincristine showed that SO significantly(P < 0.05) decrease the second phase of vincristine-induced pain.Morphine decreased vincristine-induced pain in the first and second phase of formalin test significantly(P < 0.05).In comparison,morphine showed analgesic effects in the first phase and SO extract showed significant(P < 0.05) anti-inflammatory effects in the second phase of formalin test.CONCLUSION:Both SO and vincristine showed analgesic and painful neuropathic effects,suggesting that SO extract could be useful in the treatment of vincristine-induced peripheral neuropathic pain. | Ali Namvaran Abbas Abad Mir Hadi Khayate Nouri Farzaneh Tavakkoli | 2011 | 中国天然药物2011，9，5： | 3 |
| 6 | Combination of sensitivity and uncertainty analyses for sediment transport modeling in sewer pipes显示文摘Mitigation of sediment deposition in lined open channels is an essential issue in hydraulic engineering practice.Hence,the limiting velocity should be determined to keep the channel bottom clean from sediment deposits.Recently,sediment transport modeling using various artificial intelligence(AI)techniques has attracted the interest of many researchers.The current integrated study highlights unique insight for modeling of sediment transport in sewer and urban drainage systems.A novel methodology based on the combination of sensitivity and uncertainty analyses with a machine learning technique is proposed as a tool for selection of the best input combination for modeling process at non-deposition conditions of sediment transport.Utilizing one to seven dimensionless parameters,127 models are developed in the current study.In order to evaluate the different parameter combinations and select the training and testing data,four strategies are considered.Considering the densimetric Froude number(Fr)as the dependent parameter,a model with independent parameters of volumetric sediment concentration(CV)and relative particle size(d/R)gave the best results with a mean absolute relative error(MARE)of 0.1 and a root means square error(RMSE)of 0.67.Uncertainty analysis is applied with a machine learning technique to investigate the credibility of the proposed methods.The percentage of the observed sample data bracketed by 95%predicted uncertainty bound(95PPU)is computed to assess the uncertainty of the best models. | Isa Ebtehaj Hossein Bonakdari Mir Jafar Sadegh Safari Bahram Gharabaghi Amir Hossein Zaji Hossien Riahi Madavar Zohreh Sheikh Khozani Mohammad Sadegh Es-haghi Aydin Shishegaran Ali Danandeh Mehr | 2020 | International Journal of Sediment Research2020，35，2： | 2 |
| 7 | Toxicity assessment of polyethylene microplastics in combination with a mix of emerging pollutants on Physalaemus cuvieri tadpoles显示文摘Studies in recent years have shown that aquatic pollution by microplastics(MPs)can be considered to pose additional stress to amphibian populations.However,our knowledge of how MPs affect amphibians is very rudimentary,and even more limited is our understanding of their effects in combination with other emerging pollutants.Thus,we aimed to evaluate the possible toxicity of polyethylene MPs(PE-MPs)(alone or in combination with a mix of pollutants)on the health of Physalaemus cuvieri tadpoles.After 30 days of exposure,multiple biomarkers were measured,including morphological,biometric,and developmental indices,behavioral parameters,mutagenicity,cytotoxicity,antioxidant and cholinesterase responses,as well as the uptake and accumulation of PE-MPs in animals.Based on the results,there was no significant change in any of the parameters measured in tadpoles exposed to treatments,but induced stress was observed in tadpoles exposed to PE-MPs combined with themixture of pollutants,reflecting significant changes in physiological and biochemical responses.Through principal component analysis(PCA)and integrated biomarker response(IBR)assessment,effects induced by pollutants in each test group were distinguished,confirming that the exposure of P.cuvieri tadpoles to the PE-MPs in combination with a mix of emerging pollutants induces an enhanced stress response,although the uptake and accumulation of PE-MPs in these animalswas reduced.Thus,our study provides newinsight into the danger to amphibians of MPs coexisting with other pollutants in aquatic environments. | Amanda Pereira da Costa Araújo Thiarlen Marinho da Luz Mohamed Ahmed Ibrahim Ahmed Mir Mohammad Ali Md.Mostafizur Rahman Bojan Nataraj Daniela de Melo e Silva DamiàBarceló Guilherme Malafaia | 2023 | Journal of Environmental Sciences2023，，5： | 2 |
| 8 | SYNTHESIS AND CHARACTERIZATION OF NANOSTRUCTURED-SEGMENTED BLOCK COPOLYETHERAMIDE BASED ON NYLON6 AND POLY(ETHYLENE OXIDE)显示文摘Segmented block copolymer based on nylon6(N6) and polyethylene oxide(PEO) with stochiometric ratio was synthesized via a two-step process.The first step represents end capping of N6 in the presence of adipic acid leading to carboxy terminated N6,and the second one is polycondensation of the latter product with PEO in the presence of catalyst and thermostabilizer to form a high molecular weight multi-block copolymer.Several methods were applied to characterize the synthesized copolymer such as Fourier transform infrared spectroscopy,proton nuclear magnetic resonance spectroscopy,differential thermal analysis,differential scanning calorimetry,X-ray diffraction and atomic force microscopy. The obtained results confirmed the multi-block structure for copolymer with a very high degree of micro-phase separation. Atomic force microscopy micrographs indicated that the morphology was the dispersion of high stiffness nanostructured polyamide(PA) domains in the amorphous region of PEO matrix,which can be very important in their performance for membrane processes. | Majid Peyravi Masoomeh Akhfash Ardestani Ali Akbar Babaluo Mir Karim Razavi Aghjeh Seyed Roohollah Pishghadam Elham Jannatdoust | 2010 | Chinese Journal of Polymer Science2010，28，4： | 2 |
| 9 | Anti-inflammatory and antioxidant activity of Ficus carica Linn. leaves显示文摘 | B. Ali M. Mujeeb V. Aeri S.R. Mir M. Faiyazuddin F. Shakeel | 2012 | Natural Product Research2012，，5： | 1 |
| 10 | Anti - diabetic activity of Ficus carica L stem barks and isolation of two new flavanol esters from the plant by using spectroscopical techniques 显示文摘 | Bhat M Ali D M Mir S R | 2013 | Asian Journal of Biomedical and Pharmaceutical Sciences2013，3，18： | 1 |
| 11 | Derivatization and microextraction methods for determination of organic compounds by gas chromatography显示文摘 | Mir Ali Farajzadeh Nina Nouri Parisa Khorram | 2013 | Trends in Analytical Chemistry2013，，： | 1 |
| 12 | Simultaneous derivatization and dispersive liquid–liquid microextraction of anilines in different samples followed by gas chromatography–flame ionization detection显示文摘 | Mir Ali Farajzadeh Nina Nouri | 2012 | Talanta2012，，： | 1 |
| 13 | Spatial distribution and source apportionment of heavy metals in soils of Gebeng industrial city, Malaysia显示文摘 | Mohammed Amjed Hossain Nasly M. Ali Mir Sujaul Islam H. M. Zakir Hossain | 2015 | Environmental Earth Sciences2015，，1： | 1 |
| 14 | Solvent exchange using hollow fiber prior to separation and determination of some antioxidants by high performance liquid chromatography显示文摘 | Mir Ali Farajzadeh Jan Ake Jonsson | | 0，，594： | 1 |
| 15 | A robust optimization approach to closedloop supply chain network design under uncertainty显示文摘 | Mir Saman Pishvaee Masoud Rabbani Seyed Ali Torabi | | 0，，02： | 1 |
| 16 | Evaluation of a new method for chemical coating of aluminum wire with molecularly imprinted polymer layer. Application for the fabrication of triazines selective solid-phase microextraction fiber显示文摘 | Djavanshir Djozan Bahram Ebrahimi Mehrdad Mahkam Mir Ali Farajzadeh | 2010 | Analytica Chimica Acta2010，，1： | 1 |
| 17 | Enh anced mech anicalpr oper ties of th er mosensitive ch itosan h y dr ogel by silk fiber sfor car tilage tissue engineer ing 显示文摘 | Fer esh teh Mir ah madi Moh ammad Tafazzoli- Sh adpour Moh ammad Ali Sh ok r gozar | 2013 | Mater ials Science and En-gineer ing C2013，33，8： | 1 |
| 18 | Domain sturcture of Herpes simplex virus 1 glycoprotein B: Neutmlizing epitopes map in regions of continuous and discontinuous residues 显示文摘 | Lenore P Mir Ali Konstantin K Bin H and Banks T | 1989 | Virology1989，172，1： | 1 |
| 19 | Adsorption characteristics of wheat bran towards Heavy metal cations显示文摘 | Mir Ali Farajzadeh Akbar Boviery Monji | 2004 | Separation and Purication Technology2004，38，： | 1 |
| 20 | Chrysin protects against cisplatin-induced colon. toxicity via amelioration of oxidative stress and apoptosis: Probable role of p38MAPK and p53显示文摘 | Rehan Khan Abdul Quaiyoom Khan Wajhul Qamar Abdul Lateef Mir Tahir Muneeb U Rehman Farrah Ali Sarwat Sultana | 2011 | Toxicology and Applied Pharmacology2011，，： | 1 |
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