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6篇 您的检索式:作者名="Alison Brooks"
    题名 作者 年代 出处 被引量
1Highly active iron and cobalt catalysts for the polymerization of ethylene 显示文摘Brooke L Small Maurice Brookhart Alison M A Bennett 1998J Am Chem Soc1998,120,16:1
2Can Nervous Nelly negotiate? How anxiety causes negotiators to make low first offers, exit early, and earn less profit显示文摘Alison Wood Brooks Maurice E. Schweitzer 2011Organizational Behavior and Human Decision Processes2011,,:1
3Highly active iron and cobalt catalysts for the polymerization of ethylene显示文摘Brooke Small Maurice Brookhart Alison M A Bennett 1998J Am Chem Soc1998,120,16:1
4Therapeutic applications of mesenchymal stromal cells显示文摘Gary Brooke Matthew Cook Chris Blair Rachel Han Celena Heazlewood Ben Jones Melinda Kambouris Kate Kollar Steven McTaggart Rebecca Pelekanos Alison Rice Tony Rossetti Kerry Atkinson 2007Seminars in Cell and Developmental Biology2007,,6:1
5The revolution that wasn’t: a new interpretation of the origin of modern human behavior显示文摘Sally Mcbrearty Alison S. Brooks 2000Journal of Human Evolution2000,,5:1
6Are EPB41 and alpha-synuclein diagnostic biomarkers of sport-related concussion?Findings from the NCAA and Department of Defense CARE Consortium显示文摘Background:Current protein biomarkers are only moderately predictive at identifying individuals with mild traumatic brain injury or concussion.Therefore,more accurate diagnostic markers are needed for sport-related concussion.Methods:This was a multicenter,prospective,case-control study of athletes who provided blood samples and were diagnosed with a concussion or were a matched non-concussed control within the National Collegiate Athletic Association-Department of Defense Concussion Assessment,Research,and Education Consortium conducted between 2015 and 2019.The blood was collected within 48 h of injury to identify protein abnormalities at the acute and subacute timepoints.Athletes with concussion were divided into 6 h post-injury(0-6 h post-injury)and after 6 h postinjury(7-48 h post-injury)groups.We applied a highly multiplexed proteomic technique that used a DNA aptamers assay to target 1305proteins in plasma samples from athletes with and without sport-related concussion.Results:A total of 140 athletes with concussion(79.3%males;aged 18.71±1.10 years,mean±SD)and 21 non-concussed athletes(76.2%males;19.14±1.10 years)were included in this study.We identified 338 plasma proteins that significantly differed in abundance(319 upregulated and 19 downregulated)in concussed athletes compared to non-concussed athletes.The top 20 most differentially abundant proteins discriminated concussed athletes from non-concussed athletes with an area under the curve(AUC)of 0.954(95%confidence interval:0.922-0.986).Specifically,after 6 h of injury,the individual AUC of plasma erythrocyte membrane protein band 4.1(EPB41)and alpha-synuclein(SNCA)were 0.956 and 0.875,respectively.The combination of EPB41 and SNCA provided the best AUC(1.000),which suggests this combination of candidate plasma biomarkers is the best for diagnosing concussion in athletes after 6 h of injury.Conclusion:Our data suggest that proteomic profiling may provide novel diagnostic protein markers and that a combination of EPB41 and SNCA is the most predictive biomarker of concussion after 6 h of injury.Rany Vorn Christina Devoto Timothy B.Meier Chen Lai Sijung Yun Steven P.Broglio Sara Mithani Thomas W.McAllister Christopher C.Giza Hyung-Suk Kim Daniel Huber Jaroslaw Harezlak Kenneth L.Cameron Gerald McGinty Jonathan Jackson Kevin M.Guskiewicz Jason P.Mihalik Alison Brooks Stefan Duma Steven Rowson Lindsay D.Nelson Paul Pasquina Michael A.McCrea Jessica M.Gill the CARE Consortium Investigators 2023Journal of Sport and Health Science2023,12,3:0
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