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| 1 | Upper gastrointestinal bleeding in Scotland 2000-2010: Improved outcomes but a significant weekend effect显示文摘AIM: To assess numbers and case fatality of patients with upper gastrointestinal bleeding(UGIB),effects of deprivation and whether weekend presentation affected outcomes.METHODS: Data was obtained from Information Services Division(ISD) Scotland and National Records of Scotland(NRS) death records for a ten year period between 2000-2001 and 2009-2010. We obtained data from the ISD Scottish Morbidity Records(SMR01) database which holds data on inpatient and daycase hospital discharges from non-obstetric and nonpsychiatric hospitals in Scotland. The mortality data was obtained from NRS and linked with the ISD SMR01 database to obtain 30-d case fatality. We used 23 ICD-10(International Classification of diseases) codes which identify UGIB to interrogate database. We analysed these data for trends in number of hospital admissions with UGIB,30-d mortality over time and assessed effects of social deprivation. We compared weekend and weekday admissions for differences in 30-d mortality and length of hospital stay. We determined comorbidities for each admission to establish if comorbidities contributed to patient outcome. RESULTS: A total of 60643 Scottish residents were admitted with UGIH during January,2000 and October,2009. There was no significant change in annual number of admissions over time,but there was a statistically significant reduction in 30-d case fatality from 10.3% to 8.8%(P < 0.001) over these 10 years. Number of admissions with UGIB was higher for the patients from most deprived category(P < 0.05),although case fatality was higher for the patients from the least deprived category(P < 0.05). There was no statistically significant change in this trend between 2000/01-2009/10. Patients admitted with UGIB at weekends had higher 30-d case fatality compared with those admitted on weekdays(P < 0.001). Thirty day mortality remained significantly higher for patients admitted with UGIB at weekends after adjusting for comorbidities. Length of hospital stay was also higher overall for patients admitted at the weekend when compared to weekdays,although only reached statistical significance for the last year of study 2009/10(P < 0.0005). CONCLUSION: Despite reduction in mortality for UGIB in Scotland during 2000-2010,weekend admissions show a consistently higher mortality and greater lengths of stay compared with weekdays. | Asma Ahmed Matthew Armstrong Ishbel Robertson Allan John Morris Oliver Blatchford Adrian J Stanley | 2015 | World Journal of Gastroenterology2015,21,38: | 4 |
| 2 | Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack显示文摘 | S Claiborne Johnston Peter M Rothwell Mai N Nguyen-Huynh Matthew F Giles Jacob S Elkins Allan L Bernstein Stephen Sidney | 2007 | 2007 (9558)2007,,9558: | 3 |
| 3 | 血脂、脂蛋白和载脂蛋白作为心肌梗死风险标志物(INTER-HEART研究):在52个国家进行的一项病例对照研究显示文摘背景载脂蛋白作为冠心痛的标志物是否优于血脂和脂蛋白,目前存在广泛争议。本研究旨在对载脂蛋白和胆固醇作为急性心肌梗死风险指标进行比较.
方法在52个国家的12461例急性心肌梗死患者和14637例年龄(±5岁)、性别匹配的对照者中进行了一项有关急性心肌梗死的大型、标准化病例对照研究。获得了9345例急性心肌梗死患者和12120例对照者的非空腹血液样本。测定了血脂、脂蛋白和载脂蛋白浓度,并计算了胆固醇和栽脂蛋白比值通过比较五分位数的上四位与最低位,计算每一总体测值和每一种族组的优势比(0R)及其95%CI以及人群归因危险度(PAR)。
结果载脂蛋白B100(ApoB)/载脂蛋白A1(ApoA1)比值的PAR最高(54%),其每一标准差差别的OR最高(1.59,95%CI1.53~1.64)。LDL胆固醇/HDL-胆固醇比值的PAR为37%;总胆固醇/HDL-胆固醇的PAR为32%,其显著低于ApoB/A1比值的PAR(P〈0.0001)。这些结果在所有种族组、男女两性组及所有年龄组均一致。
结论在所有种族组、男女两性组及所有年龄组,非空腹ApoB/A1比值在评估急性心肌梗死风险方面优于任何胆固醇比值,其应当被引入全世界的临床实践中。 | Matthew J McQueen Steven Hawken Xingyu Wang Stephanie Ounpuu Allan Sniderman Jeffrey Probstfield Krisela Steyn John E Sanderson Mahammad Hasani Emilia Volkova Khawar Kazmi Salim Yusuf 郭战宏(译) | 2008 | 世界临床医学2008,2,6: | 3 |
| 4 | Efficacy of selective laser trabeculoplasty following incisional glaucoma surgery显示文摘AIM: To evaluate the efficacy of selective laser trabeculoplasty(SLT) in glaucomatous eyes with previous incisional glaucoma surgery. METHODS: A retrospective cohort of eyes that underwent SLT at a single institution from 2013-2015 were followed for 1 y. Reduction in intraocular pressure(IOP) following SLT was evaluated in eyes with prior trabeculectomy with Ex Press mini shunt(Alcon, Ft Worth, TX, USA), Ahmed valve(New World Medical, Cucamonga, CA, USA), or combined phacoemulsification-trabeculectomy. A control group was included with eyes without prior surgery that underwent SLT. Success was defined as >20% drop in IOP from pre-SLT baseline. RESULTS: One-hundred and six eyes were included with 53 in both the prior glaucoma surgery(PGS) and no prior glaucoma surgery(NPGS) groups. Mean pre-SLT IOP was 19.2±4.3 and 20.6±6.0 mm Hg for PGS and NPGS groups, respectively(P=0.17). Both groups produced statistically significant IOP reductions at 1 and 6 mo(P<0.04). At 6 mo, mean IOP reduction reached 7.3% and 10.8% for the PGS and NPGS groups, respectively(P=0.42). Overall, 27.9% and 31.7% of eyes in PGS and NPGS groups met success criteria at 1 y(P=0.70). In the PGS group, eyes with baseline IOP ≥21 mm Hg had IOP reductions of 18.1%(P<0.001), 16.7%(P<0.01), and 8.4%(P=0.31) compared to eyes with baseline IOP <21 mm Hg who had IOP reductions of 2.3%(P=0.39), 3.4%(P=0.19), and 1.1%(P=0.72) at 1, 6 mo, and 1 y, respectively. CONCLUSION: SLT is efficacious in eyes with prior incisional glaucoma surgery and results in similar IOP reductions compared to eyes without PGS. A larger IOP reduction is observed following SLT in eyes with higher pre-SLT IOP. | Robert Allan Sharpe Leah L Kammerdiener David B.Williams Sudeep K.Das Matthew J.Nutaitis | 2018 | International Journal of Ophthalmology(English edition)2018,11,1: | 3 |
| 5 | Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack显示文摘 | S Claiborne Johnston Peter M Rothwell Mai N Nguyen-Huynh Matthew F Giles Jacob S Elkins Allan L Bernstein Stephen Sidney | 2007 | The Lancet . 2007 (9558)2007,,9558: | 2 |
| 6 | Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack显示文摘 | S Claiborne Johnston Peter M Rothwell Mai N Nguyen-Huynh Matthew F Giles Jacob S Elkins Allan L Bernstein Stephen Sidney | 2007 | The Lancet2007,,9558: | 2 |
| 7 | Practice Parameter for the Assessment and Treatment of Children and Adolescents With Posttraumatic Stress Disorder显示文摘 | Judith A. Cohen Oscar Bukstein Heather Walter R. Scott Benson Allan Chrisman Tiffany R. Farchione John Hamilton Helene Keable Joan Kinlan Ulrich Schoettle Matthew Siegel Saundra Stock Jennifer Medicus | 2010 | Journal of the American Academy of Child & Adolescent Psychiatry2010,,4: | 1 |
| 8 | Methylene blue chromoendoscopy for detection of short-segment Barrett’s esophagus显示文摘 | Prateek Sharma Margarita Topalovski Matthew S. Mayo Allan P. Weston | 2001 | Gastrointestinal Endoscopy2001,,: | 1 |
| 9 | Gravity spinning of polycaprolactone fibres for applications in tissue engineering显示文摘 | Matthew R. Williamson Allan G.A. Coombes | 2003 | Biomaterials2003,,3: | 1 |
| 10 | A perspective on tile optimisation of hard carbon and related coatings for engineering applications显示文摘 | Stephane Neuville Allan Matthews | 2007 | Thin Solid Films2007,515,17: | 1 |
| 11 | A novel mutation in the IHH gene causes brachydactyly type A1: a 95-year-old mystery resolved显示文摘 | Elizabeth M. McCready Elizabeth Sweeney Allan E. Fryer Dian Donnai Akeel Baig Lemuel Racacho Matthew L. Warman Alasdair G. Hunter Dennis E. Bulman | 2002 | Human Genetics (-)2002,,4: | 1 |
| 12 | Sequence variation in the Newcastle disease virus genome 显示文摘 | JACQUELINE A K MATTHEW P S ALLAN R G | 2006 | Virus Reasereh2006,,116: | 1 |
| 13 | Investigation of abradable seal coating performance using scratch testing显示文摘 | Xiao Ma Allan Matthews | | 0,,: | 1 |
| 14 | Evaluation of abradable seal coating mechanical properties显示文摘 | Xiao Ma Allan Matthews | 2009 | Wear2009,,9: | 1 |
| 15 | Lipids, lipoproteins, and apolipoproteins as risk markers of myocardial infarction in 52 countries (the INTERHEART study): a case-control study显示文摘 | Matthew J McQueen Steven Hawken Xingyu Wang Stephanie Ounpuu Allan Sniderman Jeffrey Probstfield Krisela Steyn John E Sanderson Mohammad Hasani Emilia Volkova Khawar Kazmi Salim Yusuf | 2008 | The Lancet2008,,9634: | 1 |
| 16 | Carbon and oxygen isotopes as diagenetic and stratigraphic tools:Data from subsurface of Barbados,West Indies显示文摘 | Allan J R Matthews R K | 1977 | Geology1977,5,: | 1 |
| 17 | Modelling the Deformation Behaviour of Multilayer Coatings显示文摘 | Allan Matthews Richard Jones Stephen Dowey | 2001 | Tribology Letters2001,,2: | 1 |
| 18 | The role of renqing in mediating customer relationship investment and relationship commitment in China显示文摘 | Guicheng Shi Yizheng Shi Allan K.K. Chan Matthew Tingchi Liu Kim-Shyan Fam | 2010 | Industrial Marketing Management2010,,4: | 1 |
| 19 | Investigation of abradable seal coating performance using scratch testing 显示文摘 | Ma Xiao Matthews Allan | 2007 | Surface and Coatings Technology2007,202,: | 1 |
| 20 | Methylene blue chromoendoscopy for detection of short-segment Barrett’s esophagus显示文摘 | Prateek Sharma Margarita Topalovski Matthew S. Mayo Allan P. Weston | 2001 | Gastrointestinal Endoscopy2001,,3: | 1 |