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| 1 | Development of early gastric cancer 4 and 5 years after complete remission of Helicobacter pyloriassociated gastric low-grade marginal zone B-cell lymphoma of MALT type显示文摘AIM To report 3 of 120 patients on the German MALT lymphoma trial with H. pYlori-associated gastric MALT Iymphoma who developed early gastric cancer 4 and 5 years, after complete Iymphoma remission following cure of H. pylori infection.PATIENTS AND RESULTS Three patients (two men, 74 and 70 years; one women, 77 years)with H. pylori -associated low-grade MALTlymphoma achieved complete lymphoma remission after being cured. Surveillance endoscopies were performed twice a year in accordance to the protocol. Four years aftercomplete lymphoma remission in two patients,and after 5 years in the other, early gastric adenocarcinoma of the mucosa-type, type Ⅱ a and type Ⅱ c, respectively, was detetcted,which were completely removed by endoscopic mucosa resection. in one patient, the gastric cancer was diagnosed at the same location as the previous. MALT lymphoma, in the other patients it was detected at different sites of the stomach distant from location of the previous MALT lymphoma. The patients were H. pylori negative during the whole follow-up time.CONCLUSION These findings strengthen the importance of regular long-term follow-up endoscopies in patients with complete remission of gastric MALT lymphoma after cure of H.pylori infection. Furthermore, gastric adenocarcinoma may develop despite eradication of H. pylori. | Andrea Morgner Stephan Miehlke Manfred Stolte Andreas Neubauer Birgit Alpen Christian Thiede Hermann Klann Franz-Xaver Hierlmeier Christian Ell Gerhard Ehninger Ekkehard Bayerdorffer | 2001 | World Journal of Gastroenterology2001，7，2： | 28 |
| 2 | What role does Helicobacter pylori eradicationplay in gastric MALT and gastric MALT lymphoma?显示文摘 | Morgner A Alpen B | 1997 | Gastroenterology1997，113，6： | 1 |
| 3 | 显示文摘 | ALPEN U V | 1979 | J Solid State Chem1979，29，3： | 1 |
| 4 | Universal definition of myocardial infarction显示文摘 | Thygesen K Alpen Js White HD | 2007 | J Am CollCardiol2007，50，22： | 1 |
| 5 | What role does Helicobacter pylori eradication play in gastric MALT and gastric MALT lymphoma? 显示文摘 | Morgner A Alpen B | 1997 | Gastroenterology1997，113，6： | 1 |
| 6 | A new member of the NY-ESO-1 gene family is ubiquitously expressed in somatic tissues and evolutionarily conserved显示文摘 | Alpen B Gure A O Scanlan M J | 2002 | Gene2002，297，12： | 1 |
| 7 | Molecular and cellular radiobiology of heavy ions显示文摘 | Tobias C A Lakely E A Alpen E L | 1982 | Int J Radiat Oncol Biol Phys1982，8，： | 1 |
| 8 | The RBE-LET relationship for rodent intestinal crypt cell survival, tests weight loss, and muhicellular spheroid cell survival after heavy-ion irradiation 显示文摘 | Rodriguez A Alpen E L Powers-Risius P | 1992 | Radiation Research1992，132，2： | 1 |
| 9 | Li3N: A Promising Li Ionic Conductor 显示文摘 | U V Alpen | 1979 | Journal of Solid State Chemistry1979，29，3： | 1 |
| 10 | A new member of the NY-ESO-1 gene family is ubiquitously expressed in somatic tissues and evolutionarily conserved 显示文摘 | Alpen B Gure AO Scanlan M J | 2002 | Gene2002，297，12： | 1 |
| 11 | Operative treatment of spontaneous spinal epidural hernatorna: A study of the factors determing post operative outcom显示文摘 | GROEN RJM VAN ALPEN HA | 1996 | Neurosurg1996，39，： | 1 |
| 12 | Operative treatment of spontaneous spinal epidural hematoma:A study of the factors determing post operative outcom显示文摘 | Groen RJM Van Alpen HA | 1996 | Neurosurg1996，39，： | 1 |
| 13 | Radiation effects on late cytopathological parameters in the nmrine lens relative to particle fluence显示文摘 | Tao F Powers-Risius P Alpen EL | 1994 | Adv Space Res1994，14，10： | 1 |
| 14 | Ionic conductivity in Li3N single crystals显示文摘 | Alpen U V Rabenau A Talat G H | 1977 | Applied Physics Letters1977，30，： | 1 |
| 15 | Acute coronory syndromes显示文摘 | Yun D D Alpen J S | 1997 | Cardiology1997，88，1： | 1 |
| 16 | The impact of technology on patients and families显示文摘 | Halm MA Alpen MA | 1993 | Nurs Clin North Am1993，28，2： | 1 |
| 17 | The impact of technology on patients and families显示文摘 | Halm M A Alpen M A | 1993 | Nurs Clin North Am1993，28，2： | 1 |
| 18 | 显示文摘 | Alpen U V Rabenau A Talat G H | 1977 | Appl Phys Lett1977，30，： | 1 |
| 19 | Effects short term treat- ment of hypedipidemia on coronary vasodilator function and myocardial pefiaslon in regions having substantial impairment of baseline dilator reverse显示文摘 | Huggins GS Pastemak PC Alpen NM | 1998 | Circulation1998，98，13： | 1 |
| 20 | Ionic conductivity in Li3N single crystals显示文摘 | Alpen U V Rabenau A Talat G H | | 0，，12： | 1 |
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