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9篇 您的检索式:作者名="Alpini P"
    题名 作者 年代 出处 被引量
1c-Met targeted therapy of cholangiocarcinoma显示文摘Cholangiocarcinoma continues to be a challenging disease to treat. Systemic therapy is used in unresectable disease, disease progression after surgery, and in the palliative setting. Unfortunately, results of multiple phase Ⅱ trials have rarely yielded positive results. As data on the molecular carcinogenesis of cholangiocarcinoma is developing, we are more able to understand the disease process and can use this understanding to create unique targeted therapies. We reviewed the role of c-Met/ hepatocyte growth factor (HGF) in the development of cholangiocarcinoma. Furthermore, we explored the use of the c-Met guided cascade as a target to treat cholangiocarcinoma. We reviewed the current use and options for future development of c-Met agents to treat this disease.Matei P Socoteanu Frank Mott Gianfranco Alpini Arthur E Frankel 2008World Journal of Gastroenterology2008,14,19:16
2Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans显示文摘Omenetti Alessia Porrello Alessandro Jung Youngmi Yang Liu Popov Yury Choi Steve S Witek Rafal P Alpini Gianfranco Venter Juliet Vandongen Hendrika M Syn Wing-Kin Baroni Gianluca Svegliati Benedetti Antonio Schuppan Detlef Diehl Anna Mae 2008Journal of Clinical Investigation2008,,10:3
3Estrogens stimulate prohferation of intrahepatic bihary epithelium in rats 显示文摘Alvaro D Alpini G Onori P 2000Gastroenterology2000,119,6:1
4Estrogens stimulate proliferation of intrahepatic biliary epithelium in rats 显示文摘Alvaro D Alpini G Onori P 2000Gastroenterology2000,119,6:1
5Estrogens stimulate proliferation of intrahepatic biliary epithelium in rats 显示文摘ALVARO D ALPINI G ONORI P 2000Gastroenterology2000,119,6:1
6Regulation of placenta growth factor by microRNA-125bin hepatocellular cancer显示文摘ALPINI G GLASER S S ZHANG J P 2011J Hepatol2011,55,:1
7Serotonin metabolism is dys- regulated in cholangiocarcinoma, which has implications for tumor growth显示文摘Alpini G Invemizzi P Gaudio E 2008Cancer Res2008,68,22:1
8Morphological and functional features of hepatic cyst epithelium in autosomal dominant polycystic kidney disease显示文摘Alvaro D Onori P Alpini G 2008Am J Pathol2008,172,2:1
9Alfa and beta estrogen receptors and the biliary tree显示文摘Domenico-Alvaro G Alpini P Onori A 2002Mol Cell Endocrinol2002,193,:1
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