|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Identification of quantitative trait loci and candidate genes for primary metabolite content in strawberry fruit显示文摘Improvement of nutritional and organoleptic quality of fruits is a key goal in current strawberry breeding programs.The ratio of sugars to acids is a determinant factor contributing to fruit liking,although different sugars and acids contribute in varying degrees to this complex trait.A segregating F1 population of 95 individuals,previously characterized for several fruit quality characters,was used to map during 2 years quantitative trait loci(QTL)for 50 primary metabolites,L-ascorbic acid(L-AA)and other related traits such as soluble solid content(SSC),titratable acidity(TA),and pH.A total of 133 mQTL were detected above the established thresholds for 44 traits.Only 12.9%of QTL were detected in the 2 years,suggesting a large environmental influence on primary metabolite content.An objective of this study was the identification of key metabolites that were associated to the overall variation in SSC and acidity.As it was observed in previous studies,a number of QTL controlling several metabolites and traits were co-located in homoeology group V(HG V).mQTL controlling a large variance in raffinose,sucrose,succinic acid,and L-AA were detected in approximate the same chromosomal regions of different homoeologous linkage groups belonging to HG V.Candidate genes for selected mQTL are proposed based on their co-localization,on the predicted function,and their differential gene expression among contrasting F1 progeny lines.RNA-seq analysis from progeny lines contrasting in L-AA content detected 826 differentially expressed genes and identified Mannose-6-phosphate isomerase,FaM6PI1,as a candidate gene contributing to natural variation in ascorbic acid in strawberry fruit. | JoséG.Vallarino Delphine M.Pott Eduardo Cruz-Rus Luis Miranda Juan J.Medina-Minguez Victoriano Valpuesta Alisdair R.Fernie JoséF.Sánchez-Sevilla Sonia Osorio Iraida Amaya | 2019 | Horticulture Research2019，6，1： | 3 |
| 2 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 3 | Prevalence of intestinal schistosomiasis in pre-school aged children: a pilot survey in Marolambo District, Madagascar显示文摘School-aged children(SAC)have a considerable burden of intestinal schistosomiasis in Madagascar yet its burden in pre-school aged children(PSAC)is currently overlooked.To assess the at-risk status of PSAC,we undertook a pilot epidemiological survey in June 2019 examining children(n=89),aged 2-4-years of balanced gender,in six remote villages in Marolambo District,Madagascar.Diagnosis included use of urine-circulating cathodic antigen(CCA)dipsticks and coproscopy of stool with duplicate Kato-Katz(K-K)thick smears. | Caitlin Sheehy Heather Lawson Emmanuel H.Andriamasy Hannah J.Russell Alice Reid Gina U.Raderalazasoa Graham Dodge Robbie Kornitschky James M.StJPenney Tahiry N.Ranaivoson Antsa Andria niaina Jenny S.Emmanoela Amaya L.Bustinduy JRussell Stothard Louis Andrianjaka Stephen A.Spencer | 2021 | Infectious Diseases of Poverty2021，10，3： | 2 |
| 4 | Tumor angiogenesis and node of metastasis in patients with colorectal cancer 显示文摘 | Amaya H Matsumuta M | 1997 | Cancer Res1997，57，6： | 1 |
| 5 | Correlation between expression of vascular edothelial growth factor and tumor vascularity and patient outcome in human gastric carcinoma显示文摘 | Amaya H Matsumara | 1997 | J Clin Oncol1997，15，6： | 1 |
| 6 | Expression of a dominant negative mutant of the FGFreceptor disrupts mesoderm formation in Xenopus embryos显示文摘 | 5,Amaya E Musci TJ Kirschner MW | 1991 | Cell1991，66，： | 1 |
| 7 | Roles of oxidants and redox signaling in the pathogenesis of acute respiratory distress syndrome 显示文摘 | Tasaka S Amaya F Hashimoto S | 2008 | Antioxid Redox Signal2008，10，4： | 1 |
| 8 | Purifica- tion of proteins fused to either the amino or carboxy terminus of the Mycobacterium xenopi gyrase A intein 显示文摘 | Southworth M W Amaya K Evans T C | 1999 | Biotechniques1999，27，： | 1 |
| 9 | A Methodological Framework for the Study of Residential Location and Travel-to-work Mode Choice under Central and Suburban Employment Destination patterns 显示文摘 | Amaya V Aisling R F | 2009 | Transportation Research Part A2009，43，： | 1 |
| 10 | Antibiotic resistance pat terns in gram-negative and gram positive bacteria causing sep ticemia in newborns in Leon,Nicaragua:correlation with environmental samples显示文摘 | Amaya E Caceres M Fanc H | | 0，，1： | 1 |
| 11 | Emissions of C&D refuse in land- fills : A European case 显示文摘 | Ana L6pez Amaya Lobo | 2014 | Waste Management2014，34，8： | 1 |
| 12 | Causes and mechanisms of cerebellar infarction in young patients显示文摘 | Barinagarrementeria F Amaya LE Cantu C | 1997 | Stroke1997，28，12： | 1 |
| 13 | Correlation between expression of vascular endothelial growth factor and tumor vascularity,and patient outcome in human gastric carcinoma显示文摘 | Amaya H Matsumura M | 1997 | J Clin Oncol1997，15，2： | 1 |
| 14 | Extent of tumor vascularization correlates with prognosis and hematogenous metastasis in gastric carcinoma显示文摘 | Tanagawa N Amaya H Hatsumura H | 1996 | Cancer Res1996，56，： | 1 |
| 15 | Influence of synthesis conditions on mercury adsorption capacity of propylthiol functionalized SBA-15 obtained by co-condensation显示文摘 | José Aguado Jesús M. Arsuaga Amaya Arencibia | 2007 | Microporous and Mesoporous Materials2007，，1： | 1 |
| 16 | Angiotensin lI acti- vates MAP kinase and NF - KB through angiotensin II type I re- ceptor in human pancreatic cancer ceils 显示文摘 | AMAYA K OHTA T KITAGAWA H | 2004 | Int J Oncol2004，25，4： | 1 |
| 17 | The capacitated arc routing problem with refill points显示文摘 | Alberto Amaya Andr6 Langevin | 2007 | Operations Research Letters2007，35，： | 1 |
| 18 | Correlationbetween express of vascular endothelial growth factor and tumor vascular and patient outcome in human gastric carcinoma 显示文摘 | Amaya H Matsumura M | 1997 | J Clin Oncol1997，15，2： | 1 |
| 19 | MR-guided interventional breast procedures Considering vacuum biopsy in particular 显示文摘 | Heinig A Amaya B | 2002 | Eur J Radiol2002，42，： | 1 |
| 20 | Tumor angiogenesis and mode of metastasis in patients with colorectal cancer显示文摘 | Tanigawa N Amaya H Mastumura M | 1997 | Caner Res1997，57，6： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员