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| 1 | Personalising pancreas cancer treatment:When tissue is the issue显示文摘The treatment of advanced pancreatic cancer has not moved much beyond single agent gemcitabine until recently when protocols such as FOLFIRINOX(fluorouracil,leucovorin,irinotecan and oxaliplatin)and nab-paclitaxelgemcitabine have demonstrated some improved outcomes.Advances in technology especially in massively parallel genome sequencing has progressed our understanding of the biology of pancreatic cancer especially the candidate signalling pathways that are involved in tumourogenesis and disease course.This has allowed identification of potentially actionable mutations that may be targeted by new biological agents.The heterogeneity of pancreatic cancer makes tumour tissue collection important with the aim of being able to personalise therapies for the individual as opposed to a one size fits all approach to treatment of the condition.This paper reviews the developments in this area of translational research and the ongoing clinical studies that will attempt to move this into the everyday oncology practice. | Katrin M Sjoquist Venessa T Chin Lorraine A Chantrill Chelsie O'Connor Chris Hemmings David K Chang Angela Chou Marina Pajic Amber L Johns Adnan M Nagrial Andrew V Biankin Desmond Yip | 2014 | World Journal of Gastroenterology2014，20，24： | 2 |
| 2 | Swamlata S, Cyclodextrin based novel drug delivery systems 显示文摘 | Amber V Shailendra S | 2008 | J Incl Phenom Macrocycl Chem2008，62，： | 1 |
| 3 | The Use of An- tioxidants in Radiotherapy-Induced Skin Toxicity显示文摘 | Amber K T Shiman M I Badiavas E V | 2013 | Inte- grative Cancer Therapies2013，，23： | 1 |
| 4 | A new spermidine alkaloid from Capparis decidua 显示文摘 | AHMAD V U ARIF S AMBER A U | 1985 | Heterocycles1985，23，12： | 1 |
| 5 | A new alkaloid from root bark of Capparis decidua 显示文摘 | AHMAD V U ARIF S AMBER A U | 1986 | Org Chem1986，41，8： | 1 |
| 6 | Capparisinine, a new alkaloid from Capparis decidua 显示文摘 | AHMAD V U ARIF S AMBER A U | 1987 | Liebigs Ann Chem1987，，2： | 1 |
| 7 | Isocodonocarpine from Capparis decidua 显示文摘 | AHMAD V U ISMAIL N AMBER A U | 1989 | Phytochemistry1989，28，9： | 1 |
| 8 | Odontin and odontiein, two new eudesmane sesquiterpenes from Pluchea arguta 显示文摘 | Ahmad V U Fizza K Amber A R | 1989 | J Nat Prod1989，52，4： | 1 |
| 9 | Patterns,procedures,and indications for pediatric surgery in a Tanzanian Refugee Camp:a 20-year experience显示文摘Background There are 103 million displaced people worldwide,41%of whom are children.Data on the provision of surgery in humanitarian settings are limited.Even scarcer is literature on pediatric surgery performed in humanitarian settings,particularly protracted humanitarian settings.Methods We reviewed patterns,procedures,and indications for pediatric surgery among children in Nyarugusu Refugee Camp using a 20-year retrospective dataset.Results A total of 1221 pediatric surgical procedures were performed over the study period.Teenagers between the ages of 12 and 17 years were the most common age group undergoing surgery(n=991;81%).A quarter of the procedures were performed on local Tanzanian children seeking care in the camp(n=301;25%).The most common procedures performed were cesarean sections(n=858;70%),herniorrhaphies(n=197;16%),and exploratory laparotomies(n=55;5%).Refugees were more likely to undergo exploratory laparotomy(n=47;5%)than Tanzanian children(n=7;2%;p=0.032).The most common indications for exploratory laparotomy were acute abdomen(n=24;44%),intestinal obstruction(n=10;18%),and peritonitis(n=9;16%).Conclusions There is a significant volume of basic pediatric general surgery performed in the Nyarugusu Camp.Services are used by both refugees and local Tanzanians.We hope this research will inspire further advocacy and research on pediatric surgical services in humanitarian settings worldwide and illuminate the need for including pediatric refugee surgery within the growing global surgery movement. | Sarah Rapaport Zachary Obinna Enumah Hilary Ngude Daniel S Rhee Mohamed Abbas Amber Lekey Peter J Winch Joseph V Sakran Kent A Stevens | 2023 | World Journal of Pediatric Surgery2023，6，3： | 0 |
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