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1篇 您的检索式:作者名="Ana M.Contento"
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1Analysis of penicillamine using Cu-modified graphene quantum dots synthesized from uric acid as single precursor显示文摘A simple methodology was developed to quantify penicillamine(PA) in pharmaceutical samples, using the selective interaction of the drug with Cu-modified graphene quantum dots(Cu-GQDs). The proposed strategy combines the advantages of carbon dots(over other nanoparticles) with the high affinity of PA for the proposed Cu-GQDs, resulting in a significant and selective quenching effect. Under the optimum conditions for the interaction, a linear response(in the 0.10–7.50 μmol/L PA concentration range) was observed. The highly fluorescent GQDs used were synthesized using uric acid as single precursor and then characterized by high resolution transmission electron microscopy, Raman spectroscopy, X-ray diffraction, Fourier transform infrared spectroscopy, fluorescence, and absorption spectroscopy. The proposed methodology could also be extended to other compounds, further expanding the applicability of GQDs.Gema M.Durán Tomás E.Benavidez Ana M.Contento Angel Ríos Carlos D.García 2017Journal of Pharmaceutical Analysis2017,7,5:0
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