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您的检索式：作者名="Anbarasu C"
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| 1 | Multiplex ananlysis of cytokines/chemokines as biomarkers that differenti- ate healthy contacts from tuberculosis patients in high endem- ic settings显示文摘 | Anbarasu D Ponnu Raja C Alamelu Raja | 2013 | Cytokine2013，61，： | 1 |
| 2 | Protective effect of Pisonia aculeata on thioacetamide induced hepatotoxicity in rats显示文摘Objective:To evaluate the protective effect of Pisonia aculeata(P.aculeata) on thioacetamide induced hepatotoxicity in rats.Methods:Male Wistar rats were administered 250 or 500 mg/kg p.o.of P.aculeata extract for 21 days and simultaneously administered thioacetamide(TAA) 50 mg/kg bw s.c.1 h alter the respective assigned treatments every 72 h.At the end of all experimental methods,all the animals were sacrificed by cervical decapitation.Blood samples were collected.Serum was separated and analyzed for various biochemical parameters.Results:TAA induced a significant rise in aspartate amino transferase(AST),alanine amino transferase(ALT),alkaline phosphatase(ALP),total bilirubin,gamma glutamate transpeptidase(GGTP),lipid peroxidase(LPO)with a reduction of total protein,superoxide dismutase(SOD),catalase,glutathione peroxidase(GPx) and glutathione S-transferase(GST).Treatment of rats with different does of plant extract(250 and 500 mg/kg) significantly(P<0.001) altered serum marker enzymes and antioxidant levels to near normal against TAA treated rats.The activity of the extract at a dose of 300 tug/kg was comparable to the standard drug,silymarin(50 mg/kg.p.o.).Conclusions:It can be concluded that P.aculeata extract possesses a remarkable hepaloprolective and antioxidant activity against TAA induced hepatotoxicitv.Wore research is required lo derive an optimal therapeutic dose. | Anbarasu C Rajkapoor B Bhat KS John Giridharan A Arul Amuthan Satish K | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，7： | 0 |
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