|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Gastroenteropancreatic neuroendocrine tumours显示文摘 | Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin | 2008 | Lancet Oncology2008，，1： | 8 |
| 2 | Oxidative and nitrosative stress enzymes in relation to nitrotyrosine in Helicobacter pylori-infected humans显示文摘AIM: To compare a possible relation between Helicobacter pylori(H. pylori) and the oxygen- and nitrogen radical system in humans. METHODS: Mechanisms for H. pylori to interfere with the oxygen and nitrogen radical system is of great importance for understanding of the H. pylori persistence and pathogenesis. Biopsies were obtained from the gastric wall of 21 individuals. Ongoing infection with H. pylori was detected using direct analyze from the biopsies using campylobacter-like organism test(CLO-test) and/or by using 14C-urea breath test. The individuals were divided in a negative H. pylori and a positive H. pylori group. Expression in the gastric mucosa of induc-ible nitric oxide syntase(iNOS), nicotinamide adenine dinucleotide phosphate-oxidase(NADPH-oxidase) myeloperoxidase(MPO), and nitrotyrosine were assessed by Western blotting.RESULTS: The individuals who undervent gastroscopy were divided in a H. pylori neg. [n = 13, m/f = 7/6, age(mean) = 39] and a H. pylori pos. group [n = 8, m/f = 5/3, age(mean) = 53]. Using western blot analysis iNOS was detected as a 130 kDa band. The iNOS expression was upregulated in the antrum of H. pylori infected individuals in comparison to the controls, mean ± SD being 12.6 ± 2.4 vs 8.3 ± 3.1, P < 0.01. There was a markedly upregulated expression of MPO in the antrum of H. pylori infected individuals in comparison to the control group without infection. In several of noninfected controls it was not possible to detect any MPO expression at all, whereas the expression was high in all the infected subjects, mean ± SD being 5.1 ± 3.4 vs 2.1 ± 1.9, P < 0.05. The NADPH-oxidase expression was analysed by detecting the NADPH-oxidase subunit p47-phox expression. P47-phox was detected as a 47 kDa band using Western blot, and showed a significantly higher expression of p47-phox in the antrum of the H. pylori infected individuals compared to the controls, mean ± SD being 3.1 ± 2.2 vs 0.3 ± 0.2, P < 0.01. Regarding nitrotyrosine formation, Western blot did not show any significant increase or decrease compared to controls, 7.0 ± 0.9 vs 6.9 ± 1.1, not significant.CONCLUSION: iNOS, MPO and NADPH-oxidase was up-regulated among H. pylori infected. Regarding nitrotyrosine no difference was found. This support an H. pylori related inhibition of radical formation. | Anders Elfvin Anders Edebo Peter Hallersund Anna Casselbrant Lars Fndriks | 2014 | World Journal of Gastrointestinal Pathophysiology2014，5，3： | 5 |
| 3 | Effects of ciprofloxacin on eucaryotic pyrimidine nucleotide biosynthesis and cell growth显示文摘 | Arne F Anders B | 1987 | Antimicrob Agents Chemother1987，31，5： | 2 |
| 4 | Hepatic and extrahepatic malignancies in primary sclerosing cholangitis显示文摘 | Annika Bergquist Anders Ekbom Rolf Olsson Dan Kornfeldt Lars L??f ?ke Danielsson Rolf Hultcrantz Stefan Lindgren Hanne Prytz Hanna Sandberg-Gertzén Sven Almer Fredrik Granath Ulrika Broomé | 2002 | Journal of Hepatology2002，，3： | 2 |
| 5 | Two-dimensional mathematical model of reciprocating room-temperature active magnetic regenerator显示文摘 | Thomas F P Nini P Anders S | 2008 | International Journal of Refrigeration2008，31，3： | 1 |
| 6 | Staphylococcus saprophyticus ATCC 15305 is internalized into human urinary bladder carcinoma cell line 5637显示文摘 | Szabados F Kleine B Anders A | 2008 | FEMS Microbiol Lett2008，285，2： | 1 |
| 7 | Generator maintenance scheduling to maximize reliability and revenue 显示文摘 | Silva A M L Anders G J Manso L A F | 2001 | Power Tech Proceedings2001，4，10： | 1 |
| 8 | Combustion of methane over a PdAl2O3/SiO2 catalyst,catalyst activity and stability显示文摘 | Anders F A Claes U O | 1997 | Applied Catalysis A1997，153，12： | 1 |
| 9 | Strain localization in solution heat treated Al-Zn-Mg alloys显示文摘 | Alexander F Anders S Hans J R | 2001 | Materials Science and Engineering A2001，300，： | 1 |
| 10 | Bonding in MgSi and Al-Mg-Si compounds relevant to Al-Mg-Si alloys显示文摘 | ANDERS G F RAGNVALD H | 2003 | Phys Rev B2003，67，22： | 1 |
| 11 | Effect of calcium ions on the irreversible denaturation of a recombinant Bacillus halmapalus α-am- ylase:a calorimetric investigation显示文摘 | ANDERS D N CLAUS C F PETER W | 2003 | Biochemistry Journal2003，373，： | 1 |
| 12 | Strain localization in solution heat treated Al-Zn-Mg alloys显示文摘 | Alexander F Anders S Huns J R | 2001 | Materials Science and Engineering2001，300，： | 1 |
| 13 | Role of nutrient limitation and stationary-phase existence in Klebsiella pneumoniae biofilm resistance to ampicillin and ciprofloxacin显示文摘 | Ander JN Zahller J Roe F | 2003 | Antimicrob Agents Chemother2003，4，： | 1 |
| 14 | Separation and characterization of modified variants of recombinant human insulin - like growth factor Ⅰ derived from a fusion protein secreted from Esdterichia coli显示文摘 | Goran F Grnnar P Anders E | 1990 | Biochem1990，271，： | 1 |
| 15 | Leukocyte - platelet aggregates in acuteand subacute ischemic atroke显示文摘 | Marquardt L Anders C Buggle F | 2009 | Cerebrovasc Dis2009，28，： | 1 |
| 16 | Original article results and analysis of the 2008- 2009 Insulin In-jection Technique Question- naire survey显示文摘 | Carina DE Anders F Ruth G | 2010 | Journal of Diabetes2010，2，3： | 1 |
| 17 | Genetic relationships and isozyme variability in the Heterodera avenae complex determined by isoelectrofocusing显示文摘 | Anders M F Romero M D Montes M J | 2001 | Plant Pathology2001，50，： | 1 |
| 18 | Hybridoma antibody immunoassays for the detection of parasitic infection: further studies on a monoclonal antibody with immunodiagnostic potential for Schistosomiasis japonica显示文摘 | Cruise K M Mitchell G F Garcia E G Anders R F | 1981 | Acta Trop1981，38，4： | 1 |
| 19 | Leukocyte-platelet aggregates in acute and subacute ischemic stroke 显示文摘 | Marquardt L Anders C Buggle F | 2009 | Cerebrovasc Dis2009，28，3： | 1 |
| 20 | Leukocyte- platelet ag gregates in acute and subacute ischemic stroke显示文摘 | Marquardt L Anders C Buggle F | 2009 | Cerebrovasc Dis2009，28，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员