|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Development and evaluation of a safe and effective sugar-free herbal lollipop that kills cavity-causing bacteria显示文摘Dental caries (tooth decay) is caused by a specific group of cariogenic bacteria, like Streptococcus mutans, which convert dietary sugars into acids that dissolve the mineral in tooth structure. Killing cariogenic bacteria is an effective way to control or prevent tooth decay. In a previous study, we discovered a novel compound (Glycyrrhizol A), from the extraction of licorice roots, with strong antimicrobial activity against cariogenic bacteria. In the current study, we developed a method to produce these specific herbal extracts in large quantities, and then used these extracts to develop a sugar-free lollipop that effectively kills cariogenic bacteria like Streptococcus mutans. Further studies showed that these sugar-free lollipops are safe and their antimicrobial activity is stable. Two pilot human studies indicate that a brief application of these lollipops (twice a day for ten days) led to a marked reduction of cariogenic bacteria in oral cavity among most human subjects tested. This herbal lollipop could be a novel tool to promote oral health through functional foods. | Chu-hong Hu Jian He Randal Eckert Xiao-yang Wu Li-na Li Yan Tian Renate Lux Justin A. Shuffer Faina Gelman Janet Mentes Sue Spackman Janet Bauer Maxwell H. Anderson Wen-yuan Shi | 2011 | International Journal of Oral Science2011，3，1： | 3 |
| 2 | Impact of COVID-2019 on stroke services in China: survey from the Chinese Stroke Association显示文摘Background The COVID-19 pandemic and physical distancing guidelines have compelled stroke practices worldwide to reshape their delivery of care significantly.We aimed to illustrate how the stroke services were interrupted during the pandemic in China.Methods A 61-item questionnaire designed on Wenjuanxing Form was completed by doctors or nurses who were involved in treating patients with stroke from 1 February to 31 March 2020.Results A total of 415 respondents completed the online survey after informed consent was obtained.Of the respondents,37.8%,35.2%and 27.0%were from mild,moderate and severe epidemic areas,respectively.Overall,the proportion of severe impact(reduction>50%)on the admission of transient ischaemic stroke,acute ischaemic stroke(AIS)and intracerebral haemorrhage(ICH)was 45.0%,32.0%and 27.5%,respectively.Those numbers were 36.9%,27.9%and 22.3%;36.5%,22.1%and 22.6%;and 66.4%,47.5%and 41.1%in mild,moderate and severe epidemic areas,respectively(all p<0.0001).For AIS,thrombolysis was moderate(20%-50%reduction)or severely impacted(>50%),as reported by 54.4%of the respondents,while thrombectomy was 39.3%.These were 44.4%,26.3%;44.2%,39.4%;and 78.2%,56.5%,in mild,moderate and severe epidemic areas,respectively(all p<0.0001).For patients with acute ICH,39.8%reported the impact was severe or moderate for those eligible for surgery who had surgery.Those numbers were 27.4%,39.0%and 58.1%in mild,moderate and severe epidemic areas,respectively.For staff resources,about 20%(overall)to 55%(severe epidemic)of the respondents reported moderate or severe impact on the on-duty doctors and nurses.Conclusion We found a significant reduction of admission for all types of patients with stroke during the pandemic.Patients were less likely to receive appropriate care,for example,thrombolysis/thrombectomy,after being admitted to the hospital.Stroke service in severe COVID-19 epidemic areas,for example,Wuhan,was much more severely impacted compared with other regions in China. | Xia Wang Menglu Ouyang Cheryl Carcel Chen Chen Lingli Sun Jie Yang Yao Zhang Guofang Chen Shoujiang You Yongjun Cao Lu Ma Xin Hu Yi Sui Craig Anderson Lili Song Yongjun Wang David Wang | 2020 | Stroke & Vascular Neurology2020，5，4： | 2 |
| 3 | Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor显示文摘 | Anne Brunet Azad Bonni Michael J Zigmond Michael Z Lin Peter Juo Linda S Hu Michael J Anderson Karen C Arden John Blenis Michael E Greenberg | 1999 | Cell1999，，6： | 2 |
| 4 | Ultrasound Molecular Imaging of Tumor Angiogenesis With an Integrin Targeted Microbubble Contrast Agent显示文摘 | Christopher R. Anderson Xiaowen Hu Hua Zhang Jose Tlaxca Anne-Emilie Declèves Robert Houghtaling Kumar Sharma Michael Lawrence Katherine W. Ferrara Joshua J. Rychak | 2011 | Investigative Radiology2011，，4： | 2 |
| 5 | A wheat intervarietal genetic linkage map based on microsatellite and target region amplified polymorphism markers and its utility for detecting quantitative trait loci 显示文摘 | LIU Z H ANDERSON J A HU J FRIESEN T L RASMUSSEN J B FARIS J D | 2005 | Theoretical and Applied Genetics2005，111，4： | 1 |
| 6 | Ultrasound mo-lecular imaging of tumor angiogenesis with an integrin targeted microbubble contrast agent显示文摘 | Anderson CR Hu X Zhang H | 2011 | Invest Radiol2011，46，4： | 1 |
| 7 | Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by Ephrin-B2,and its receptor Eph B4显示文摘 | Wang HU Chen ZF Anderson DJ | 1998 | Cell1998，93，5： | 1 |
| 8 | High-dose-rate in- traoperative radiation therapy (HDR-IORT) for retroperi- toneal sarcomas显示文摘 | Alektiar KM Hu K Anderson L | 2000 | Int J Radiat Oncol Biol Phys2000，47，1： | 1 |
| 9 | Activated microglia inhib?it multiplication of Toxoplasma gondii via a nitric oxide mecha?nism显示文摘 | Chao CC Anderson WR Hu S | 1993 | Clin Immunol Irnmunopathol1993，67，2： | 1 |
| 10 | Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor EphB 4 显示文摘 | Wang HU Chen ZF Anderson DJ | 1998 | Cell1998，93，5： | 1 |
| 11 | High- dose- rate intraoperative radiation therapy (HDRIORT) for retroperitoneal sarcomas 显示文摘 | Alektiar KM Hu K Anderson L | 2000 | Int J Radiat Oncol Biol Phys2000，47，1： | 1 |
| 12 | Genetic linkage map based on microsatellite and target region amplified polymorphism markers and its utility for detecting quantitative trait loci 显示文摘 | Liu ZH Anderson JA Hu J | 2005 | Theor Appl Genet2005，111，： | 1 |
| 13 | Ultrasound molecular imaging of tumor angiogenesis with an integrin targeted mien) buhhle contrast agent 显示文摘 | Anderson CB Hu X Zhang H | 2011 | Invest Radiol2011，46，4： | 1 |
| 14 | Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4 显示文摘 | Wang HU Chen ZF Anderson DJ | 1998 | Cell1998，93，5： | 1 |
| 15 | Ultrasound molecular imaging of tumor angiogenesis with an integrin targeted microbubble contrast agent显示文摘 | Anderson CR Hu X Zhang H | 2011 | Invest Radiol2011，46，： | 1 |
| 16 | A wheat intervarietal genetic linkage map based on microsatellite and target region amplified polymorphism markers and its utility for detecting quantitative trait loci显示文摘 | Liu Z H Anderson J A Hu J | 2005 | Theor Appl Genet2005，111，： | 1 |
| 17 | High- dose- rate intraoperative radiation therapy (HDR-IORT) for retroperitoneal sarcomas显示文摘 | Alektiar KM Hu K Anderson L | 2000 | Int J Radiat Oncol Biol Phys2000，47，1： | 1 |
| 18 | Plant regeneration capacity of mesophyll protoplasts from Brassica napus and related species 显示文摘 | HU Q ANDERSON S B HANSEN L N | 1999 | Plant Cell1999，50，： | 1 |
| 19 | Isolation and characterization of rice R genes: evidence for distinct evolutionary paths in rice and maize显示文摘 | Hu J Anderson B Wessler S R | 1996 | Genetics1996，142，3： | 1 |
| 20 | Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4 显示文摘 | Wang HU Chert ZF Anderson DJ | 1998 | Cell1998，93，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员