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| 1 | Efficacy and safety of endoscopic prophylactic treatment with undiluted cyanoacrylate for gastric varices显示文摘AIM:To evaluate the efficacy and safety of undiluted N-butyl-2 cyanoacrylate plus methacryloxysulfolane(NBCM)as a prophylactic treatment for gastric varices(GV)bleeding.METHODS:This prospective study was conducted at a single tertiary-care teaching hospital between October 2009 and March 2013.Patients with portal hypertension(PH)and GV,with no active gastrointestinal bleeding,were enrolled in primary prophylactic treatment with NBCM injection without lipiodol dilution.Initial diagnosis of GV was based on endoscopy and confirmed with endosonography(EUS); the same procedure was used after treatment to confirm eradication of GV.After puncturing the GV with a regular injection needle,1 mL of undiluted NBCM was injected intranasally into GV.The injection was repeated as necessary to achieve eradication or until a maximum total volume of 3 mL of NBCM had been injected.Patients were followed clinically and evaluated with endoscopy at 3,6 and 12 mo.Later follow-ups were performed yearly.The main outcome measures were efficacy(GV eradication),safety(adverse events related to cyanoacrylate injection),recurrence,bleeding from GV and mortality related to GV treatment.RESULTS:A total of 20 patients(15 male)with PH and GV were enrolled in the study and treated with undiluted NBCM injection.Only 2(10%)patients had no esophageal varices(EV); 18(90%)patients were treated with endoscopic band ligation to eradicate EV before inclusion in the study.The patients were followed clinically and endoscopically for a median of 31 mo(range:6-40 mo).Eradication of GV was observed in all patients(13 patients were treated with 1 session and 7 patients with 2 sessions),with a maximum injected volume of 2 mL NBCM.One patient had GV recurrence,confirmed by EUS,at 6-mo follow-up,and another had late recurrence with GV bleeding after 35 mo of follow-up; overall,GV recurrence was observed in 2 patients(10%),after 6 and 35 mo of follow-up,and GV bleeding rate was 5%(1 patient).Mild epigastric pain was reported by 3 patients(15%).No mortality or major complications,including embolism,or damage to equipment were observed.CONCLUSION:Endoscopic injection with NBCM,without lipiodol,may be a safe and effective treatment for primary prophylaxis of gastric variceal bleeding. | Matheus Cavalcante Franco Gustavo Flores Gomes Frank Shigeo Nakao Gustavo Andrade de Paulo Angelo Paulo Ferrari Jr Ermelindo Della Libera Jr | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，6： | 16 |
| 2 | Association of Helicobacter pylori infection and giardiasis: Results from a study of surrogate markers for fecal exposure among children显示文摘AIM: To investigate whether Helicobacter pylori (H pykori)infection is associated with hepatitis A virus (HAV) infection, presence of enteroparasites, and other surrogates of fecal exposure.METHODS: We conducted a cross-sectional study in 121 children consecutively admitted at a pediatric hospital inSalvador, Brazil.H pylori and HAV infection were identified by the presence of serum antibodies. Stool specimens were examined for the presence of ova and parasites. A structured questionnaire inquiring about sanitary conditions and life style was applied to each subject. RESULTS: Fifty-one of the 121 children (42.1%) werefound to be seropositive for H pylori, and 45 (37.2%) for HAV. The seroprevalence ofHpyloriand HAV both increased significantly with age. Cross-tabulation of data showed that 26 (21.5%) were seropositive and 51 (42.1%) were negative for bothHpyloriand HAV antibodies (χ2 = 7.18,OR = 2.8, CI 1.30-5.97). The age adjusted OR for an HAV-infected child being H pylori positive was 2.3 (CI1.02-5.03). The agreement between H pylori and HAVseropositivity was fair (κ = 0.24). After controlling for possible confounding, the variables remaining independently associated with seropositivity to H pyloriwere age,presence of Giardia lamblia in feces (OR = 3.2, 95%CI, 1.1-9.5) and poor garbage disposal quality (OR = 2.4,95%CI, 1.1-5.1).CONCLUSION: Our data suggest that H pylori infection is associated with surrogate markers of fecal exposure. Thus, we conclude that the fecal-oral route is relevant in the transmission of HP among children in an urban setting of a developing country. The association observed between G. lamblia and H pylori infection may have several explanations. Further studies to investigate this relationship are warranted. | Edson Duarte Moreira Jr Victor Bastos Nassri Rafaela Sousa Santos Junísia Ferraz Matos Wilson Andrade de Carvalho Célia Stolve Silvani Círia Santana e Sant'Ana | 2005 | World Journal of Gastroenterology2005，11，18： | 3 |
| 3 | Apollonian networks:simultaneously scale-free,small world,euclidean,space filling, and with matching Graphs显示文摘 | Andrade Jr J S Herrmann H J Andrade R F S | 2005 | Physical Review Letters2005，94，： | 1 |
| 4 | Accuracy of FDG-PET to diagnose lung cancer in a region of endemic granuloma- tous disease 显示文摘 | Deppen S Putnam JB Jr Andrade G | 2011 | Ann Thorac Surg2011，92，2： | 1 |
| 5 | Preliminary experience with decompressive ventriculostomy by continuous ventricular cerebrospinal fluid drainage in post traumatic diffuse brain swelling显示文摘 | Andrade AF Marion JR Miura FK | | 0，，09： | 1 |
| 6 | Anterior occipito cervical fusion using an extra-pharyngeal exposure显示文摘 | De Andrade JR Macnab I | 1969 | Bone Joint Surg Am1969，512，： | 1 |
| 7 | Body adiposity and its influence on clinical and metabolic parameters of patients with type 1 diabetes显示文摘 | ANDRADE CR JR CLEMENTE EL GOMES MDE B | 2004 | Arq Bras Endocrinol Metabol2004，48，6： | 1 |
| 8 | Thoracoscopy in children and adolescents 显示文摘 | de Gmpos JR Andrade Filho LO Werebe EC Minamoto H Quim AO Filomeno LT | 1997 | Chest1997，111，2： | 1 |
| 9 | Value of rapid betalocker injection at peak dobutamine-atropine stress echocardiography for detection of coronary artery disease显示文摘 | Mathias W Jr Tsutsui JM Andrade JL | 2003 | J Am Coll Cardiol2003，41，7： | 1 |
| 10 | In vitro ef- fects of sildenafil and phentolamine, drugs used for erec- tile dysfunction,on human sperm motility 显示文摘 | Andrade JR Traboulsi A Hussain A | 2000 | Am J Ob- stet Gynecol2000，182，5： | 1 |
| 11 | Endocardial border delineation during dobutamine infusion using contrast echocardiography显示文摘 | Mathias W Jr Arruda AL Andrade JL | 2002 | Echocardiography2002，19，2： | 1 |
| 12 | Thermostatistics of overdamped motion of interacting particles显示文摘 | Andrade Jr J S Da Silva G F T Moreira A A | 2010 | Physical review letters2010，105，26： | 1 |
| 13 | Gene expression profile analysis of primary glioblastomas and non-neoplastic brain tissue: identifi cation of potential target genes by oligonucleotide microarray and real-time quantitative PCR显示文摘 | Scrideli C A Carlotti C G Jr Okamoto O K Andrade V S Cortez M A Motta F J | 2008 | J Neurooncol2008，88，： | 1 |
| 14 | How to make a fragile network robust and vice versa 显示文摘 | Moreira A A Jr Andrade J S Herrmann H S Indekeu J O | 2009 | Phys Rev Lett2009，102，01： | 1 |
| 15 | A superconducting high-speed flywheel energy storage system显示文摘 | Andrade Jr R de Ferreira A C Sotelo G G | 2004 | Physica C2004，，： | 1 |
| 16 | Value ofrapid beta-blocker injection at peak dobutamine-atropinestress echocardiography for detection of coronary arterydisease显示文摘 | Mathias W Jr Tsutsui JM Andrade JL | 2003 | J Am Coll Cardiol2003，41，9： | 1 |
| 17 | Effect of diabetes on orthodontic tooth movement in a mouse model显示文摘 | Braga SM Taddei SR Andrade I Jr | 2011 | Eur J Oral Sci2011，119，1： | 1 |
| 18 | The role of mechanical bowel preparation for colonic resection and anastomosis :an experimental study显示文摘 | Feres 0 Monteiro dos Santos Jr JC Andrade JI | 2001 | Int J Colorectal Dis2001，16，6： | 1 |
| 19 | Confinement of the electrical signal for in situ measurement of polarization resistance in reinforced concrete显示文摘 | Gonzalez J A Feliu S Jr Andrade M C | 1990 | ACI Materals Journal1990，87，5： | 1 |
| 20 | Surgical treatment of varicocele in children with open and laparoscopic Palomo technique: a systematic review of the literature 显示文摘 | Barroso U Jr Andrade D M Novaes H | 2009 | J Urol2009，181，6： | 1 |
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