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| 1 | Compared efficacy of preservation solutions on the outcome of liver transplantation:Meta-analysis显示文摘AIM To compare the effects of the four most commonly used preservation solutions on the outcome of liver transplantations.METHODS A systematic literature search was performed using MEDLINE, Scopus, EMBASE and the Cochrane Library databases up to January 31^(st), 2017. The inclusion criteria were comparative, randomized controlled trials(RCTs) for deceased donor liver(DDL) allografts with adult and pediatric donors using the gold standard University of Wisconsin(UW) solution or histidinetryptophan-ketoglutarate(HTK), Celsior(CS) and Institut Georges Lopez(IGL-1) solutions. Fifteen RCTs(1830 livers) were included; the primary outcomes were primary non-function(PNF) and one-year posttransplant graft survival(OGS-1). RESULTS All trials were homogenous with respect to donor and recipient characteristics. There was no statistical difference in the incidence of PNF with the use of UW, HTK, CS and IGL-1(RR = 0.02, 95%CI: 0.01-0.03, P = 0.356). Comparing OGS-1 also failed to reveal any difference between UW, HTK, CS and IGL-1(RR = 0.80, 95%CI: 0.80-0.80, P = 0.369). Two trials demonstrated higher PNF levels for UW in comparison with the HTK group, and individual studies described higher rates of biliary complications where HTK and CS were used compared to the UW and IGL-1 solutions. However, the meta-analysis of the data did not prove a statistically significant difference: the UW, CS, HTK and IGL-1 solutions were associated with nearly equivalent outcomes.CONCLUSION Alternative solutions for UW yield the same degree of safety and effectiveness for the preservation of DDLs, but further well-designed clinical trials are warranted. | Agnes Lilla Szilágyi Péter Mátrai Péter Hegyi Eszter Tuboly Daniella Pécz András Garami Margit Solymár Erika Pétervári Márta Balaskó Gábor Veres László Czopf Bastian Wobbe Dorottya Szabó Juliane Wagner Petra Hartmann | 2018 | World Journal of Gastroenterology2018,24,16: | 5 |
| 2 | Chemical shift magnetic resonance spectroscopy of cingulate grey matter in patients with minimal hepatic encephalopathy显示文摘 | Sergei Mechtcheriakov Michael Schocke André Kugener Ivo W. Graziadei Michael Mattedi Hartmann Hinterhuber Wolfgang Vogel Josef Marksteiner | 2005 | Neuroradiology2005,,1: | 1 |
| 3 | Multidimensional assessment of neuro-psychiatric symptoms in patients with low-grade hepatic encephalopathy: A clinical rating scale显示文摘AIM: To evaluate the feasibility of a new clinical rating scale for a standardized assessment of cirrhosis-associated neuro-psychiatric symptoms.METHODS: Forty patients with liver cirrhosis (LC, with or without low-grade hepatic encephalopathy) were invest-igated using a clinical neuro-psychiatric rating scale based on a comprehensive list of neurological, psychomotor,cognitive, affective, behavioral symptoms, and symptoms of disturbed bioregulation.RESULTS: The analysis revealed that the majority of cirrhotic patients showed, besides characteristic neurological symptoms of hepatic encephalopathy, various psychomotor,affective and bioregulatory symptoms (disturbed sleep and sexual dysfunction). Patients were impaired in the following subscales: sleep and biorhythm disorder (75.0% of patients), Parkinsonoid symptoms (25.0%), affective symptoms (17.5%), and psychomotor retardation (12.5%).The increase of total neuro-psychiatric clinical score was significantly associated with the degree of hepatic enceph-alopathy.CONCLUSION: This study suggests that a substantial number of patients with LC and low-grade hepatic encephalopathy manifest various clinical neuro-psychiatric symptoms. The use of a rating scale, which explores clinical dimensions of hepatic encephalopathy, would improve the management of patients with LC. | Sergei Mechtcheriakov Ivo W Graziadei André Kugener Julia Wiedemann Chantal Galbavy Hartmann Hinterhuber Josef Marksteiner Wolfgang Vogel | 2005 | World Journal of Gastroenterology2005,11,37: | 1 |
| 4 | Acrylic copolymers with perfluoroalkylated biphenyl side groups:Correlation structure-surface properties 显示文摘 | Patrice Hartmann Andre' Collet Michel Viguier | 2006 | Macromolecules2006,39,: | 1 |
| 5 | Disruption of Trp53 in Livers of Mice Induces Formation of Carcinomas With Bilineal Differentiation显示文摘 | Sarah–Fee Katz André Lechel Anna C. Obenauf Yvonne Begus–Nahrmann Johann M. Kraus Eva M. Hoffmann Johanna Duda Parisa Eshraghi Daniel Hartmann Birgit Liss Peter Schirmacher Hans A. Kestler Michael R. Speicher K. Lenhard Rudolph | 2012 | Gastroenterology2012,,5: | 1 |
| 6 | Declaring income versus declaring taxes in tax compliance experiments:Does the design of laboratory experiments affect the results?显示文摘Laboratory experiments are frequently criticised,in part because of the sensitivity of the results to specific features of the design.This paper addresses an important question regarding the key aspect of the experimental environment:How should the dependent variable–participants’choices–be operationalised?For the specific context of laboratory research on income tax compliance,we compare the effects of the two most common operationalisation types:the declaration of gross income versus the declaration of tax payment.It is found that compliance is higher when participants indicate their tax payment than when they declare their income.It is also discovered that the effects of the three policy parameters of the economic model(the tax rate,audit probability and fine rate)are stronger when participants declare their taxes than when they declare their income.These results are relevant for interpreting prior and future experimental evidence on tax compliance and can explain some contradictory previous findings.More broadly,this study suggests that the results of laboratory experiments may depend on specific features of the experimental design,which proposes a strong need for more systematic methodological research. | Stephan Muehlbacher Andre Hartmann Erich Kirchler James Alm | 2023 | Economic and Political Studies2023,11,3: | 0 |