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| 1 | 组蛋白去甲基化酶家族中组蛋白去甲基化酶4作用机制及其应用的研究进展显示文摘组蛋白甲基化是一种重要的表观遗传性修饰方式,是一个可逆的动态调节过程。组蛋白去甲基化酶家族中组蛋白去甲基化酶4能催化去除组蛋白赖氨酸残基甲基标记,调节染色质的结构,参与精细调控基因转录,维持染色质的活性和非活性平衡。组蛋白去甲基化酶4异常可能导致细胞增殖、分化、个体发育、能量代谢及肿瘤发生发展等多种生物进程异常。研究显示组蛋白去甲基化酶4可作为新的药物靶标。本文就组蛋白去甲基化酶4家族的结构、作用机制、在疾病发生发展进程中的生物学功能及特异性抑制剂开发的最新研究进展作一综述。 | 叶覃 Andreana HOLOWATYJ Roselyne M.LABBE 刘辉 ZengquanYANG | 2014 | 转化医学杂志2014，3，1： | 6 |
| 2 | Steatosis accelerates the progression of liver damage of chronic hepatitis C patients and correlates with specific HCV genotype and visceral obesity显示文摘 | Luigi E. Adinolfi Michele Gambardella Augusto Andreana Marie-fran?oise Tripodi Riccardo Utili Giuseppe Ruggiero | 2001 | Hepatology2001，，6： | 4 |
| 3 | A Systematic Review of Microvascular Invasion in Hepatocellular Carcinoma: Diagnostic and Prognostic Variability显示文摘 | Manuel Rodríguez-Perálvarez Tu Vinh Luong Lorenzo Andreana Tim Meyer Amar Paul Dhillon Andrew Kenneth Burroughs | 2013 | Annals of Surgical Oncology2013，，1： | 3 |
| 4 | Dentinal hypersensitivity : review of aetiology, differential diagnosis, prevalence, and mechanism 显示文摘 | Al-Sabbagh M Andreana S Cianeio S G | 2004 | J Int Acad Periodontol2004，6，1： | 1 |
| 5 | Serum HCV RNA levels correlate with histological liver damdge and concur with steatosis in progression of chronic hepatitis C显示文摘 | Adinolfi LE Utili R Andreana A | 2001 | Dig Dis Sci2001，46，： | 1 |
| 6 | Noncarious cervical lesions and abfractions:A re-evaluation显示文摘 | Litonjua LA Andreana S Bush PJ | 2003 | J Am Dent Assoe2003，134，7： | 1 |
| 7 | Crown lengthnig:basic principles,indications,techniques and clinical case显示文摘 | Yeh S Andreana S | | 0，，08： | 1 |
| 8 | Serum HCV RNA levels correlate with histological liver damage and concur with steatosis in progression of chronic hepatitis C显示文摘 | Adinolfi LE Utili R Andreana A | 2001 | Dig Dis Sci2001，46，8： | 1 |
| 9 | Hepatic fibrosis plays a central role in the pathogenesis of thrombocytopenia in patients with chronic viral hepatitis显示文摘 | Adinolfi LE Giordano MG Andreana A | 2001 | Br J Haematol2001，113，： | 1 |
| 10 | A syste- matic review of microvascular invasion in hepatocellular carcino- ma: diagnostic and prognostic variability 显示文摘 | Rodriguez-Peralvarez M Luong TV Andreana L | 2013 | Ann Surg Oncol2013，20，1： | 1 |
| 11 | Extraction socket preservationgraft before implant placement with Calcium sulfate hemihydrateand platelet-rich plasma: a clinical and histomorphometric study inhumans显示文摘 | Kutkut A Andreana S Kim HL | 2012 | J Periodontol2012，83，4： | 1 |
| 12 | Serum HOV RNA levels correlate with histological liver damage and concur with steatosis in progression of chronic hepatitis C显示文摘 | Adinolfi LE UtiIi R Andreana A | 2001 | Dig Dis Sci2001，46，8： | 1 |
| 13 | Collagen:An overview显示文摘 | Patino MG Neiders ME Andreana S | 2002 | Implant Dentistry2002，11，3： | 1 |
| 14 | Collagen:an overview显示文摘 | Patino MG Neiders ME Andreana S | 2002 | Implant Dent2002，11，： | 1 |
| 15 | Noncarious cervical lesions and abfractions: a re-evaluation 显示文摘 | Litonjua LA Andreana S Bush PJ | 2003 | J Am Dent Assoc2003，134，7： | 1 |
| 16 | Toothbru- shing and gingival recession显示文摘 | Litonjua LA Andreana S Bush PJ | 2003 | Int Dent J2003，53，2： | 1 |
| 17 | A systematic review of microvascular invasion in hepatocellular carcinoma:diagnostic and prognostic variability显示文摘 | Rodríguez-Perálvarez M Luong TV Andreana L | 2013 | Annals Surg Oncolo2013，20，1： | 1 |
| 18 | Dentinal hypersensitivity:review of aetiology,differential diagnosis,prevalence,and mechanism显示文摘 | Al-Sabbagh M Andreana S Ciancio SG | | 0，，01： | 1 |
| 19 | Non -carious cervical lesion and abfractions:a reevaluation 显示文摘 | Litonjua LA Andreana S Bush PJ | 2003 | J Am Dent Assoc2003，134，7： | 1 |
| 20 | Experimental features affecting the transparency of YAG ceramics 显示文摘 | Laura Esposito Andreana Piancastelli Anna Luisa Costa etal | 2011 | Optical Materials2011，33，： | 1 |
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