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| 1 | Hepatobiliary complications of alveolar echinococcosis: A long-term follow-up study显示文摘AIM:To determine the long-term hepatobiliary complications of alveolar echinococcosis(AE) and treatment options using interventional methods.METHODS:Included in the study were 35 patients with AE enrolled in the Echinococcus Multilocularis Data Bank of the University Hospital of Ulm.Patients underwent endoscopic intervention for treatment of hepatobiliary complications between 1979 and 2012.Patients' epidemiologic data, clinical symptoms, and indications for the intervention, the type of intervention and any additional procedures, hepatic laboratory parameters(pre- and post-intervention), medication and surgical treatment(pre- and post-intervention), as well as complications associated with the intervention and patients‘ subsequent clinical courses were analyzed.In order to compare patients with AE with and without history of intervention, data from an additional 322 patients with AE who had not experienced hepatobiliary complications and had not undergone endoscopic intervention were retrieved and analyzed.RESULTS:Included in the study were 22 male and 13 female patients whose average age at first diagnosis was 48.1 years and 52.7 years at the time of intervention.The average time elapsed between first diagnosis and onset of hepatobiliary complications was 3.7 years.The most common symptoms were jaundice, abdominal pains, and weight loss.Thenumber of interventions per patient ranged from one to ten.Endoscopic retrograde cholangiopancreatography(ERCP)was most frequently performed in combination with stent placement(82.9%),followed by percutaneous transhepatic cholangiodrainage(31.4%)and ERCP without stent placement(22.9%).In 14.3%of cases,magnetic resonance cholangiopancreatography was performed.A total of eight patients received a biliary stent.A comparison of biochemical hepatic function parameters at first diagnosis between patients who had or had not undergone intervention revealed that these were significantly elevated in six patients who had undergone intervention.Complications(cholangitis,pancreatitis)occurred in six patients during and in 12patients following the intervention.The average survival following onset of hepatobiliary complications was 8.8years.CONCLUSION:Hepatobiliary complications occur in about 10%of patients.A significant increase in hepatic transaminase concentrations facilitates the diagnosis.Interventional methods represent viable management options. | Tilmann Graeter Franziska Ehing Suemeyra Oeztuerk Richard Andrew Mason Mark Martin Haenle Wolfgang Kratzer Thomas Seufferlein Beate Gruener | 2015 | World Journal of Gastroenterology2015，21，16： | 6 |
| 2 | Macrophage phagocytosis of aging neutrophils in inflammation: programmed cell death in the neutrophils leads to its recognition by macrophages显示文摘 | Andrew HW Janet EH | 1989 | J Clin Invest1989，83，： | 1 |
| 3 | Clinical predic- tors for the aetiology of peripheral lymphadenopathy in HIV-infected adults 显示文摘 | Bogoch II Andrews JR Nagami EH | 2013 | HIV medicine2013，14，3： | 1 |
| 4 | Hypoxamirs in pulmonary hypertension : breathing new life into pulmonary vascular research 显示文摘 | Andrew EH Kevin W Stephen YC | 2012 | Cardiovasc Diagn Ther2012，2，3： | 1 |
| 5 | What prevents people with chronic obstructive pulmonary disease from attending pulmonary rehabilitation? A systematic review显示文摘 | Andrew K Annemarie L Anne EH | 2011 | Chronic Respiratory Dis ease2011，8，2： | 1 |
| 6 | What prevents people with chro- nic obstructive pulmonary disease from attending Pulmonary rehabil- itation? A Systematic review 显示文摘 | Andrew K Annemarie L Anne EH | 2011 | Chronic Respiratory Disease2011，8，2： | 1 |
| 7 | The distribution of poly-methyl methacrylate formed in natural rubber la-tex: An electron microscopical study显示文摘 | Andrews EH Turner DT | 1960 | Journalof Applied Polymer Science1960，3，9： | 1 |
| 8 | Adhesion of ice to a flexible sub strate显示文摘 | Andrews EH Majid H A | 1984 | Journal of Materials Science1984，19，1： | 1 |
| 9 | Successful management of spind dural arteriovenous fistulas undetected by ar- teriography显示文摘 | Oldfield EH Andrew BZ Chen MY | 2002 | J Neurosurg2002，96，2： | 1 |
| 10 | Successful management of spinal dural arteriovenous fistulas undetected by arteriography显示文摘 | Oldfield EH Andrew BE Chen MY | 2002 | J Neurosurg2002，96，2： | 1 |
| 11 | Electrocardiographic T-wave inversion:differential diagnosis in the chest pain patient显示文摘 | Geoffrey EH William JB Andrew DP | 2002 | Am J Emerg Med2002，20，3： | 1 |
| 12 | Chemistry of cephalosporin antibiotics XIV: reaction of cephalosporin C with nitrosyl chloride 显示文摘 | Morin RB Jackson BG Flynn EH Roeske RW Andrews SL | 1969 | J Am Chem Soc1969，91，6： | 1 |
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